2013
DOI: 10.1007/s10989-013-9385-5
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Purification and Characterization of Antioxidant Peptides from Oyster (Saccostrea cucullata) Hydrolysate and the Anticancer Activity of Hydrolysate on Human Colon Cancer Cell Lines

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Cited by 27 publications
(23 citation statements)
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“…Recently, several studies have been focused on the generation of bioactive peptides from food proteins and their utilization as functional ingredients [23]. Previous studies revealed that oyster is a good source of biologically active peptides with antioxidant, anti-cancer, ACE inhibitory, and anti-microbial activities in vitro and show antihypertensive activity in vivo [24,25,26,27]. Having these therapeutic potential, oysters can be considered as an alternative source of peptides that can be used as an ingredient for functional foods and nutraceuticals.…”
Section: Introductionmentioning
confidence: 99%
“…Recently, several studies have been focused on the generation of bioactive peptides from food proteins and their utilization as functional ingredients [23]. Previous studies revealed that oyster is a good source of biologically active peptides with antioxidant, anti-cancer, ACE inhibitory, and anti-microbial activities in vitro and show antihypertensive activity in vivo [24,25,26,27]. Having these therapeutic potential, oysters can be considered as an alternative source of peptides that can be used as an ingredient for functional foods and nutraceuticals.…”
Section: Introductionmentioning
confidence: 99%
“…Recently, peptides with potential antioxidant activity have been obtained from various materials, such as soy proteins [7,8], caseins [9,10], egg proteins [11], aquatic product proteins [12][13][14], and other materials.…”
Section: Introductionmentioning
confidence: 99%
“…Anti‐oxidant substances, such as flavonoids and isoflavones, can improve testicular steroidogenesis by upregulating StAR expression, which can prevent late‐onset male hypogonadism 33 . However, the peptides obtained by enzymatic hydrolysis of oyster have a good scavenging effect on potent 1,1‐diphenyl‐2‐picrylhydrazyl free radicals 34,35 . The results of the present study showed that low‐dose CP could significantly decrease GSH‐px, but increase MDA levels in testis, suggesting that during PADAM formation, the ability of scavenging ROS in testis is weakened, and the generation of free radicals is increased, which results in the damage of seminiferous tubules and interstitial cells.…”
Section: Discussionmentioning
confidence: 61%