Purcell, Edward M.: Research in Nuclear MagnetismNobel Lecture December, 11, 1952©Les Prix Nobel, 1952

Atomistic picture of conformational exchange in a T4 lysozyme cavity mutant: an experiment-guided molecular dynamics study

“…Moreover, the atoms or groups of atoms in a protein, such as the Phe114 sidechain in the case of T4L L99A, continuously collide with objects of similar size such as water and other protein atoms, so that their motion is stochastic in nature and difficult to intuit. 6 , 7 , 42 However, in favorable situations the questions posed above can be addressed using molecular dynamics (MD) simulations. In a conventional classical MD simulation, Newton's equations of motion are numerically solved to generate a movie that shows how the positions of the atoms in the system evolve with time.…”

Microfluidic devices powered by integrated elasto-magnetic pumps

“…In 1977, Purcell 13 suggested the simplest possible swimming mechanism in the Stokes regime, known as the 3-link swimmer. The 3-link swimmer is a device consisting of 3-links attached via two hinges, where the rotation angles of the hinges are controlled.…”

“…Generating net motion in the Stokes regime has been a lively area of study over the last few decades, underpinned by the work of Purcell 13 and Taylor, 14 and has grown into a diverse field with a multitude of swimming and pumping mechanisms being developed both theoretically and experimentally. Research in this field has explored a vast array of driving mechanisms, including magnetic torque, 15 – 23 electric fields, 24 , 25 light, 26 , 27 acoustic waves 28 – 30 and chemical energy.…”

“…This paper introduces a device which aims to overcome the limitations above. The research pursues the development of a multipurpose, modular micropump by exploring the validity of a design inspired by Purcell's 3-link swimmer, 13 the simplest possible swimming solution in the Stokes regime. This design is integrated within a self-contained module at the time of manufacture, requiring only soft lithography, utilising a simple external actuation method and producing highly tuneable and reversible fluid flow.…”

Desarrollo de sistemas de preconcentración "on-line" para análisis de muestras de interés biológico mediante electroforesis capilar

“…El comportamiento observado aquí concuerda con los resultados obtenidos por A. W. Purcell y coautores [244][245][246][247] que reportaron efectos similares de la T en la retención de péptidos en cromatografía de líquidos basándose en los cambios de conformación e hidrofobicidad de los mismos. Considerando los replicados que se realizaron se puede resaltar que la repetitividad fue excelente a cualquiera de las T de trabajo.…”