Pulse therapy combined with oral corticosteroids in the management of severe rheumatic carditis and rebound

Torres, Renato P. A.; Torres, Rômulo F. A.; Torres, Rafael A.; Torres, Rosângela S. L. A.

doi:10.1017/s1047951117002062

Cited by 5 publications

(3 citation statements)

References 18 publications

(26 reference statements)

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“…18 On the other hand, a study by Torres et al found that combining pulse methylprednisolone and oral prednisolone appear to contribute to both reduced left chamber dimensions and prevention of rebound phenomenon. 19 A meta-analysis of the treatment of Group A streptococcus pharyngitis to prevent acute rheumatic fever concluded that there would be an approximately 60% reduction in cases of acute rheumatic fever if pharyngitis was appropriately treated, especially in endemic areas. 20 The large number of cases among the paediatric population underlines the need for more efforts in the public health sector for primary prevention, given the relative ease and low cost of Group A streptococcus pharyngitis treatment.…”

Section: Discussionmentioning

confidence: 99%

Acute rheumatic fever in the paediatric population: a descriptive study in the Malaysian state of Sabah

2021

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Introduction: Rheumatic heart disease is among the leading causes of acquired valvular heart disease in the developing world. However, there is no data available for rheumatic heart disease in the paediatric population of Sabah. This study collected data for acute rheumatic fever admissions among the paediatric population in Sabah over a period of 3 years. Methods: This is a retrospective cohort study. All records for admissions to paediatric wards in Sabah for acute rheumatic fever from January 2016 to December 2018 were collected. The patient records were then traced and required information were collected. Results: A total of 52 cases of acute rheumatic fever were admitted. It was observed that the incidence of acute rheumatic fever was 74.4 per 100,000 paediatric admissions. Patients from the West Coast Division made up most of the admissions (n = 24, 46.2%). Male patients (n = 35, 67.3%) of the indigenous Kadazan-Dusun ethnicity (n = 21, 40.4%) were most commonly encountered. The mean age at time of presentation was 9.58 years. Most cases admitted (n = 38, 73.1%) were categorised as Priority 1 (severe rheumatic heart disease). Conclusion: Most patients who were admitted had symptoms of heart failure and were diagnosed with severe rheumatic heart disease. Although this disease is preventable, the incidence in Sabah remains high. This study was limited as we only looked at patients who were admitted and we foresee the real incidence to be higher. Hence, there is an urgent need for a rheumatic heart disease registry in Malaysia to gather more data for prevention and early intervention.

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Section: Discussionmentioning

confidence: 99%

Acute rheumatic fever in the paediatric population: a descriptive study in the Malaysian state of Sabah

2021

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“…The rebound phenomenon and rebound effects were observed after withdrawal of several drugs including beta blockers, corticosteroids, opioid drugs, antiepileptic, immunomodulatory and antidepressant agents (Fukuyama, Ganchingco, & Bäumer, 2017; Henssler, Heinz, Brandt, & Bschor, 2019; Koracevic et al., 2020; Torres, Torres, Torres, & Torres, 2018; Wilens, Zulauf, Ryland, Carrellas, & Catalina‐Wellington, 2015).…”

Section: Discussionmentioning

confidence: 99%

Pregabalin administration and withdrawal affect testicular structure and functions in rats

et al. 2020

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The aim of this prospective experimental study was to investigate the effects of pregabalin (PG) administration and withdrawal on testicular structures and functions in rats. A total of 24 male Wistar rats were divided into two groups (n = 12 each): a control group received normal saline, and PG‐treated group received 62 mg kg‐1 day‐1 PG for 2 months. Half the animals of each group were sacrificed for the collection of blood and testicular samples. The remaining animals were bred for another 2 months without treatment before collection of blood and testicular samples. PG administration decreased testosterone and increased luteinising hormone (LH) and follicle‐stimulating hormone (FSH) levels versus controls. PG withdrawal led to a decrease in both FSH and LH and an increase in testosterone levels versus saline withdrawal. Compared to controls, PG administration caused degeneration of seminiferous tubules and decreased the number of spermatogenic but increased the number of Leydig cells. After PG withdrawal, these cells showed a rebound reverse. Reduced glutathione levels increased with PG administration while PG withdrawal increased malondialdehyde levels. Conclusion: PG administration affected testicular morphometry, gonadotrophic and sex hormones; however, there was a rebound reversal in all these parameters and a significant oxidative stress in PG withdrawal.

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“…Application of remote sensing in rice has been increasing since mid 2000s with the MODIS sensors data (due to its easy access and with its higher temporal resolution or its ability to acquire the image every one or two days) and the main research objectives of rice remote sensing have been in retrieval and study of the rice characteristics such as Leaf Area Index (LAI), nitrogen and chlorophyll contents, biomass which have the guiding roles in the rice agronomic managements (Xu et al, 2022). The research publications are mostly seen from the developed nations that includes the United States of America (USA), China and Japan, but genuinely, the remote sensing has been boon in other nations as well for monitoring of rice crops mainly for the crop mapping (DDNS, 2016;Tiwari et al, 2021;Torres, 2022).…”

Section: A R T I C L E I N F Omentioning

confidence: 99%

Satellite Remote Sensing of Rice Crops in Nepal : A Review

Magar

2023

J. Agric. & Environ.

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Remote sensing, based on satellite data, is useful in studying rice crops for their several parameters such as cropped area, crop-coverage, growth stages, production, yield estimation and other statistics useful in scientific investigations. Despite some satellite-remote-sensing based researches have been reported in the country, such appliance in agricultural studies is very sparse in Nepal. In the current situation, Nepal could benefit from remote sensing technology for betterment of its agricultural planning and development specifically in the rice sub-sector for its national economic and food security importance. This review article is an attempt to highlight the importance of rice remote sensing in Nepal and list research articles in the field as bookmarks to benefit future rice researchers and interested readership.

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Pulse therapy combined with oral corticosteroids in the management of severe rheumatic carditis and rebound

Abstract: The pulse therapy was effective in controlling severe rheumatic carditis and the oral corticosteroid prevented rebound episodes. Prolonged hospital stay was required for the clinical stabilisation of patients and to avoid the interruption of medication.

Cited by 5 publications

References 18 publications

Acute rheumatic fever in the paediatric population: a descriptive study in the Malaysian state of Sabah

Acute rheumatic fever in the paediatric population: a descriptive study in the Malaysian state of Sabah

Pregabalin administration and withdrawal affect testicular structure and functions in rats

Satellite Remote Sensing of Rice Crops in Nepal : A Review

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