Pulsatile flow simulation in arterial vascular segments with intravascular ultrasound images

Liu, Y.; Lai, Yong G.; Nagaraj, Ashwin; Kane, Bonnie J.; Hamilton, Andrew J.; Greene, R. R.; McPherson, David D.; Chandran, K. B.

doi:10.1016/s1350-4533(01)00088-1

Cited by 50 publications

(33 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, a simple method of finding the role is to compare with the condition of rigid wall. According to the method, the same conclusion has been drawn by many researchers, that is, wall shear stress is decreased by the compliance of arterial wall through fluid-structure interaction [7][8][9].…”

Section: Introductionmentioning

confidence: 58%

Wall stress and deformation analysis in a numerical model of pulse wave propagation

Liu

Gao

2015

BME

View full text Add to dashboard Cite

Abstract. To simulate pulse wave propagation, we set up a wave propagation model using blood-wall interaction in previous work. In this paper, our purpose is to investigate wall stress and deformation of the wave propagation model. The finite element method is employed for solving the governing equations of blood and wall. Our results suggest that there are two peaks in the circumferential stress and strain distributions of the normal model. The stress and strain values change with the varieties of different factors, such as wall thickness and vessel diameter. The results indicate that different parameters of fluid and tube wall have remarked impact on wall stress and deformation.

show abstract

Section: Introductionmentioning

confidence: 58%

Wall stress and deformation analysis in a numerical model of pulse wave propagation

Liu

Gao

2015

BME

View full text Add to dashboard Cite

show abstract

“…However, such research did not pay much attention to the problem of specification of the boundary conditions. Boundary conditions are a substantive and indispensable issue for numerical simulation since they usually affect the computational results, especially for the blood flow in a complicated geometry (11), (12) . Nowadays, owing to the improvement of MR angiography, the velocity profile on the cross-section of a blood vessel can be obtained.…”

Section: Introductionmentioning

confidence: 99%

Numerical Study on Variation of Feedback Methods in Ultrasonic-Measurement-Integrated Simulation of Blood Flow in the Aneurysmal Aorta

Funamoto

Hayase

Saijo

et al. 2006

JSME Int. J., Ser. C

View full text Add to dashboard Cite

The complicated relationships between hemodynamics and aneurysms have been investigated intensively. However, existing methodologies have inherent limitations in providing real blood flow fields. The authors have proposed Ultrasonic-Measurement-Integrated (UMI) simulation, in which the feedback signals lead to convergence of the calculated blood flow structure to the real one even with incorrect boundary/initial conditions. In UMI simulation, determination of the feedback law is substantially important, but detailed particulars remain to be accounted for. In this paper, first, the effects of density of feedback points and feedback domains are systematically investigated. Improvement of computational accuracy in the feedback domain is achieved even in low density of feedback points of 25%, and such improvement persists in the downstream region. Secondly, the most effective combination of feedback gains for momentum and pressure equations is investigated, confirming the validity of the simple condition to use the same value for the velocity and pressure gains.

show abstract

“…Realistic representation of blood flow can be obtained by solving the fundamental equations of the flow with realistic vessel geometries obtained by medical imaging techniques such as magnetic resonance imaging (MRI) or computed tomography (CT). 3,4,8,12,15,16,24,26,30 Numerical simulation dealing with flow in an aorta with an aneurysm has also been carried out by such a combination. 3,4,26 Taylor and Yamaguchi reported the appearance and disappearance of a primary vortex and regions of high shear stresses both at the proximal and distal ends of the aneurysm.…”

Section: Introductionmentioning

confidence: 99%

“…26 Di Martino et al studied the complex mechanical interaction between blood flow and wall dynamics in a three-dimensional custom model of an abdominal aortic aneurysm and provided a quantitative local evaluation of the stresses. 3 However, numerical simulation has an inherent problem of specification of the boundary conditions, 8,12,15,16 and thus the calculated blood flow is usually similar but not identical to the real one. In order to minimize the effect of inaccurate inlet velocity profile specification on local wall shear stress computations in the vessel segment, Liu et al extended their model of the carotid artery in the upstream direction with a straight tube, proposing that such extension may be useful until more accurate, noninvasively obtained velocity profile data for the inlet become available.…”

Section: Introductionmentioning

confidence: 99%

“…In order to minimize the effect of inaccurate inlet velocity profile specification on local wall shear stress computations in the vessel segment, Liu et al extended their model of the carotid artery in the upstream direction with a straight tube, proposing that such extension may be useful until more accurate, noninvasively obtained velocity profile data for the inlet become available. 15 In the descending aorta, however, extension by adding the ascending aorta and the aortic arch does not eliminate the effect of the upstream boundary condition on reproduction of the complicated flow structure (e.g., Kilner et al observed helical and retrograde secondary flow patterns in the aortic arch using magnetic resonance velocity mapping). 13,28 By numerical simulation with an integrated model of the left ventricle and the aorta, Nakamura et al revealed that the upstream boundary condition strongly influences development of the helical flow.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Fundamental Study of Ultrasonic-Measurement-Integrated Simulation of Real Blood Flow in the Aorta

et al. 2005

View full text Add to dashboard Cite

Abstract-Acquisition of detailed information on the velocity and pressure fields of the blood flow is essential to achieve accurate diagnosis or treatment for serious circulatory diseases such as aortic aneurysms. A possible way to obtain such information is integration of numerical simulation and color Doppler ultrasonography in the framework of a flow observer. This methodology, namely, Ultrasonic-Measurement-Integrated (UMI) Simulation, consists of the following processes. At each time step of numerical simulation, the difference between the measurable output signal and the signal indicated by numerical simulation is evaluated. Feedback signals are generated from the difference, and numerical simulation is updated applying the feedback signal to compensate for the difference. This paper deals with a numerical study on the fundamental characteristics of UMI simulation using a simple two-dimensional model problem for the blood flow in an aorta with an aneurysm. The effect of the number of feedback points and the feedback formula are investigated systematically. It is revealed that the result of UMI simulation in the feedback domain rapidly converges to the standard solution, even with usually inevitable incorrect upstream boundary conditions. Finally, an example of UMI simulation with feedback from real color Doppler measurement also shows a good agreement with measurement.

show abstract

Pulsatile flow simulation in arterial vascular segments with intravascular ultrasound images

Cited by 50 publications

References 26 publications

Wall stress and deformation analysis in a numerical model of pulse wave propagation

Wall stress and deformation analysis in a numerical model of pulse wave propagation

Numerical Study on Variation of Feedback Methods in Ultrasonic-Measurement-Integrated Simulation of Blood Flow in the Aneurysmal Aorta

Fundamental Study of Ultrasonic-Measurement-Integrated Simulation of Real Blood Flow in the Aorta

Contact Info

Product

Resources

About