Pulsatile and steady‐state 24‐hour hemodynamics in adolescents and young adults: The next steps ahead

Weber, Thomas; Protogerou, Athanasios; Sharman, James E.; Wassertheurer, Siegfried

doi:10.1111/jch.13969

Cited by 2 publications

(2 citation statements)

References 28 publications

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“…Previous validation studies conducted in Western populations have shown acceptable agreement between Mobil‐O‐Graph‐derived parameters (central BP and wave reflections) and invasive and non‐invasive measurements. 37 A short height is associated with shorter wave traveling distance and earlier arrival of wave reflections to the proximal aorta causing an increase in Pa, augmentation index, and central SBP. Here, height was inversely associated with Pa and Aix@75 but not with central SBP; however, the relationship of height with Pa and Aix@75 disappeared after adjustment for sex.…”

Section: Discussionmentioning

confidence: 99%

Effects of a Low‐Salt and High‐Potassium Diet on Arterial Stiffness and Left Ventricular Function in Indigenous Papuans

Ishida

Isotani

Fujisawa

et al. 2021

JAHA

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Background A sodium‐restricted diet represents a potential non‐pharmacological strategy for improving blood pressure, arterial stiffness, and left ventricular (LV) diastolic function. We investigated age‐related differences in LV structure and function and the relationship between LV function and central hemodynamics in an indigenous Papuan population, who maintain a traditional lifestyle, including a low‐salt and high‐potassium diet. Methods and Results We measured LV dimensions, transmitral blood flow, and mitral annular tissue velocities through echocardiography and Doppler imaging. Blood pressure and brachial‐ankle pulse wave velocity were measured using an automatic device (Omron). Central blood pressure and wave reflection parameters were estimated via oscillometry (Mobil‐O‐Graph, using European calibrations). A total of 82 native Papuans (median age, 42 years; 38 women; no blood pressure treatment) were enrolled. Age‐related difference in brachial systolic pressure was modest but significant, and brachial‐ankle pulse wave velocity significantly increased with age; however, LV mass index remained unchanged. LV ejection fraction and global longitudinal strain were preserved; mitral A‐wave velocity and average E/e´ increased; and e´ and E/A decreased with age. Brachial‐ankle pulse wave velocity and spot urine Na/K were positively and independently correlated with E/e´. Age and heart rate were inversely associated with E/A. In conclusion, LV systolic function was preserved; however, LV diastolic function decreased with age in Papuans. Moreover, age‐related arterial stiffening, but not wave reflections, was inversely related to LV diastolic function. Conclusions Our results suggest that arterial and LV stiffness may not be altered by sodium restriction. Longitudinal studies are warranted to elucidate the effects of diet on arterial and LV function.

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Section: Discussionmentioning

confidence: 99%

Effects of a Low‐Salt and High‐Potassium Diet on Arterial Stiffness and Left Ventricular Function in Indigenous Papuans

Ishida

Isotani

Fujisawa

et al. 2021

JAHA

View full text Add to dashboard Cite

show abstract

“…By this method, central systolic BP was calculated using the ARCSolver® (Austrian Institute of Technology, Vienna, Austria) algorithm, which determines the aortic systolic BP. The aortic systolic BP can be calculated by the algorithm by two different calibration methods: C1 (using brachial systolic and diastolic BP), and C2 (using oscillometrically measured mean/diastolic BP) ( 8 ).…”

Section: Introductionmentioning

confidence: 99%

The usefulness of SAGE score in predicting high pulse wave velocity in hypertensive patients: a retrospective cohort study

Pereira,

Chagas,

Barbosa

et al. 2024

Front. Cardiovasc. Med.

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IntroductionAortic stiffness assessed by pulse wave velocity (PWV) is an important predictor to evaluate the risk of hypertensive patients. However, it is underutilized in clinical practice. We aimed to identify the optimal cutoff SAGE score that would indicate a risk PWV ≥ 10 m/s in Brazilian ambulatory hypertensive patients.Materials and methodsA retrospective cohort study. Patients underwent central blood pressure measurement using a validated oscillometric device from August 2020 to December 2021. A ROC curve was constructed using the Youden statistic to define the best score to identify those at high risk for PWV ≥ 10 m/s.ResultsA total of 212 hypertensive individuals were selected. The mean age was 64.0 ± 12.4 years and 57.5% were female. The following comorbidities were present: overweight (47.6%), obesity (34.3%), and diabetes (25.0%). Most of the sample (68.9%) had PWV < 10 m/s. According to Youden's statistic, a cutoff point of 6 provided the optimal combination of sensitivity and specificity for identifying patients with a PWV ≥ 10 m/s. This cutoff achieved sensitivity of 97.0%, and specificity of 82.9%. In clinical practice, however, a cutoff point of 7 (where score values of at least 7 were considered to indicate high risk) had a positive likelihood ratio of 8.2 and a negative likelihood ration of 0.346, making this the ideal choice by accurately excluding patients who are less likely to have PWV ≥ 10 m/s.ConclusionA SAGE score ≥7 identified Brazilian hypertensive patients with a high risk of PWV ≥ 10 m/s.

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Pulsatile and steady‐state 24‐hour hemodynamics in adolescents and young adults: The next steps ahead

Cited by 2 publications

References 28 publications

Effects of a Low‐Salt and High‐Potassium Diet on Arterial Stiffness and Left Ventricular Function in Indigenous Papuans

Effects of a Low‐Salt and High‐Potassium Diet on Arterial Stiffness and Left Ventricular Function in Indigenous Papuans

The usefulness of SAGE score in predicting high pulse wave velocity in hypertensive patients: a retrospective cohort study

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