2006
DOI: 10.1055/s-2005-872976 View full text |Buy / Rent full text
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Abstract: We present a case of pulmonary sclerosing hemangioma with multiple involvements. Pulmonary sclerosing hemangioma is a relatively rare neoplasm. Although it is thought to be benign, cases with lymph node metastasis or multiple pulmonary involvement have been reported in clinical settings. To date, no case has been reported with mortality due to sclerosing hemangioma, however its clinical characteristics of multiple spread and lymphnode metastasis have not yet been elucidated.

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“…1,2 This tumor is generally regarded as benign but rare cases involving lymph node metastasis [3][4][5][6][7] or multifocal lesions [8][9][10] have been reported. However, there have been no reports of pulmonary SH with pleural dissemination.…”
Section: Introductionmentioning
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“…1,2 This tumor is generally regarded as benign but rare cases involving lymph node metastasis [3][4][5][6][7] or multifocal lesions [8][9][10] have been reported. However, there have been no reports of pulmonary SH with pleural dissemination.…”
Section: Introductionmentioning
“…It is generally considered a benign malady, but several cases with lymph node metastasis or multifocal pulmonary involvement have been reported (4,5). The origin of PSH is controversial; however, recent studies on the expression levels of estrogen receptors and the markers of type II pneumocytes, such as TTF-1, MUC1, Thomsen- Table V.…”
Section: Discussionmentioning
“…Histopathological diagnosis can be confirmed through the presence of a mixture of the 4 major histological patterns and through the distinctive cellular components (surface-lining cuboidal and stromal-pale tumor cells) found within a single tumor (1)(2)(3). Several cases with lymph node metastasis or multifocal lung involvement have been reported (4,5), but did not have a bad prognosis. It is therefore thought that the nature of this tumor is between benign and malignant.…”
Section: Introductionmentioning
“…In addition, PSH may be low-grade malignancy, since cases of lymph node and lung metastases have been reported. Thus, FDG PET/CT could be useful for the differential diagnosis of low-grade malignancy of PSH, particularly when the SUVmax of PSH exceeds 2.5, or when lymph node and lung metastases are displayed on PET/CT images (9)(10)(11)(12)(13)(14), which would be of great assistance in the clinical treatment.…”
Section: Discussionmentioning
“…However, a few studies have suggested that certain benign pulmonary tumors, such as PSH, may be low-grade malignancies, since cases of lymph node and lung metastases have been reported (9)(10)(11)(12)(13)(14), or that the malignant transformation of lung benign tumors may be possible, such as the transformation of pulmonary hamartoma into adenocarcinoma, sarcoma or squamous cell carcinoma (15)(16)(17). Thus, it is also important to compare and analyze the characteristics of 18 F-FDG PET/CT in benign lung tumors and to evaluate their metabolic activities to choose the proper clinical management.…”
Section: Introductionmentioning