Pulmonary Hypertension, Right Ventricular Function, and Clinical Outcome in Acute Decompensated Heart Failure

Interaction Between Worsening Renal Function and Persistent Congestion in Acute Decompensated Heart Failure

“…16,17 Eligible patients were those hospitalized as with new-onset or worsening preexisting HF as primary cause of admission or those with significant HF symptoms that developed during the hospitalization where HF was the primary discharge diagnosis. In addition, patients were required to have at least 1 sign of congestion and a brain natriuretic peptide (BNP) level >400 pg/ml at admission, using the AxSYM BNP microparticle enzyme immunoassay (Abbott Laboratories, Abbott Park, Illinois).…”

Echocardiography in Acute Heart Failure: Current Perspectives

“…the tricuspid annular plane systolic excursion or semi-quantitatively), and LV end-diastolic and end-systolic diameters carry prognostic information. 38,47,49 In a study of 817 patients, tricuspid annular plane systolic excursion predicted short-and long-term mortality (1 and 4.1 years respectively). 49 We strongly believe that in order to establish strong prognostic echocardiographic markers, the protocol of clinical trials, regarding the timing of the echocardiogram, should be strict.…”

“…[47][48][49][50][51] Among traditional parameters, LVEF, RV function (evaluated by e.g. the tricuspid annular plane systolic excursion or semi-quantitatively), and LV end-diastolic and end-systolic diameters carry prognostic information.…”

“…A semi-quantitative assessment of RV function appears to be a marker of severity and prognosis in AHF also 47. …”

Identifying Patients Who Do Not Benefit From Transcatheter Aortic Valve Replacement

“…[17][18][19] Perhaps, teasing out the underestimation of PASP because of concomitant tricuspid regurgitation and adding RV functional estimates to PASP would enhance the discrimination between survivors and nonsurvivors after TAVR. As a result of the limitations of any single factor as a litmus test to discern benefit for patients with aortic stenosis who need therapy, one might surmise that combining factors into a score would be more helpful.…”