Pulmonary hypertension in obstructive sleep apnea hypopnea syndrome

Me, Abou Shehata; Eldesoky, Mohamed; Maaty, Abd El-Razek; Abd-ElMaksoud, Amina M.; Suliman, Lucy A.

doi:10.1016/j.ejcdt.2013.03.004

Cited by 11 publications

(1 citation statement)

References 27 publications

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“…Wan-Lu Sun et al [7] studied about the impact of obstructive sleep apnea on pulmonary hypertension in patients with chronic obstructive pulmonary disease. Abou Shehata et al [8] studied to investigate whether OSA by itself without any other cardiac or lung disease can lead to pulmonary hypertension, and to assess the effect of CPAP therapy on pulmonary artery pressure. In this study, the pulmonary hypertension between OSA and NON -OSA patients, obese and non-obese patients were observed for prevalence of pulmonary hypertension.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of pulmonary hypertension in OSA patients with obstructive airway diseases

Sudarshan¹,

Umarani²,

A³

2022

Int. J. Appl. Res.

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The aim of this study is to study the prevalence of pulmonary hypertension in obstructive sleep apnea patients with obstructive airway disease using ECHO. Subjects and method:The study was performed on 50 obstructive airway diseases (OAD) patients out of which 35 were associated with OSA. After getting informed consent, patients basic demographic details, clinical history, detailed general and systemic examination, spirometry, sleep study, Echo were performed for each patients. Results: In our study pulmonary hypertension were higher in number in OSA patients compared to the NON-OSA patients. Among the obese patients higher number of pulmonary hypertension were observed. As far as severity is concerned more number of severe pulomonary hypertension were noted in OSA and Obese patients. Conclusion: Pulmonary hypertension is invariably present in most of the OSA patients with obstructive airway diseases. Hence control of OSA by CPAP therapy in OAD patients will prevent or delay the development of pulmonary hypertension.

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Section: Introductionmentioning

confidence: 99%

Prevalence of pulmonary hypertension in OSA patients with obstructive airway diseases

Sudarshan¹,

Umarani²,

A³

2022

Int. J. Appl. Res.

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Pulmonary hypertension and echocardiogram parameters in obstructive sleep apnea

Wong

Chee

Chong

2017

Eur Arch Otorhinolaryngol

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Obstructive sleep apnea (OSA) is a growing health hazard in the United States and worldwide. OSA is now recognized as a disorder with systemic manifestations and its association with obesity and adverse cardiovascular consequences. There is increasing evidence that OSA may be associated with systemic hypertension and an increased incidence of stroke, heart failure, myocardial infarction, and arrhythmias. Less information is available about the association between OSA and pulmonary hypertension (PH). We therefore conduct this study to look at the prevalence of the pulmonary hypertension in obstructive sleep apnea patient and to identify risk factors leading to pulmonary hypertension among OSA patient. We studied and analyzed all OSA patient confirmed by polysomnograph in the year 2015. Twenty-five patients with OSA were included in this study with prevalence of pulmonary hypertension of 16%. Univariate analysis of various factors revealed a statistically significant association between having the lowest SpO of <70% and pulmonary hypertension (p = 0.016). There were no statistically significant associations between age, gender, smoking status, hypertension, body mass index (BMI), or apnea-hypopnea index (AHI) with occurrence of pulmonary hypertension. AHI is not a good predictor for pulmonary hypertension. The real value of using AHI to predict the health risk of OSA is doubtful. We recommend routine echocardiogram among OSA patient. The objective information in the echocardiogram provides evidence for counseling of patient with disease of OSA and hence hopefully can improve compliance of patient to treatment especially usage of CPAP.

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Effect of continuous positive airway pressure treatment on pulmonary artery pressure in patients with isolated obstructive sleep apnea: a meta-analysis

et al. 2016

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Pulmonary hypertension (PH) can occur in patients with obstructive sleep apnea (OSA) in the absence of cardiac or lung disease. Data on the development and severity of PH, and the effect of continuous positive airway pressure (CPAP) therapy on pulmonary artery (PA) pressures in these patients have been inconsistent in the literature. We sought to determine whether CPAP therapy affects PA pressures in patients with isolated OSA in this meta-analysis. We searched PubMed, Medline, EMBASE and other databases from January 1980 to August 2015. Studies of patients with OSA, defined as an apnea-hypopnea index >10 events/h, and PH, defined as PA pressure >25 mmHg were included. Two reviewers independently extracted data and assessed risk of bias. A total of 222 patients from seven studies (341.53 person-years) had reported PA pressures before and after treatment with CPAP therapy. 77 % of participants were men, with a mean age of 52.5 years, a mean apnea-hypopnea index of 58 events/h, and mean PA pressure of 39.3 ± 6.3 mmHg. CPAP treatment duration ranged from 3 to 70 months. Using fixed effects meta-analysis, CPAP therapy was associated with a decrease in PA pressure of 13.3 mmHg (95 % CI 12.7-14.0) in our study population. This meta-analysis found that CPAP therapy is associated with a significantly lower PA pressure in patients with isolated OSA and PH.

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Pulmonary hypertension in obstructive sleep apnea hypopnea syndrome

Cited by 11 publications

References 27 publications

Prevalence of pulmonary hypertension in OSA patients with obstructive airway diseases

Prevalence of pulmonary hypertension in OSA patients with obstructive airway diseases

Pulmonary hypertension and echocardiogram parameters in obstructive sleep apnea

Effect of continuous positive airway pressure treatment on pulmonary artery pressure in patients with isolated obstructive sleep apnea: a meta-analysis

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