Pulmonary hemorrhage in dengue: differential diagnosis with acute viral respiratory syndromes including COVID-19

Abstract

We report the case of a 6-year-old boy that presented with enlarged lymph nodes on his neck. He complained of tiredness and discouragement, which worsened during feverish periods. There were no relevant laboratory test abnormalities and serological tests were not reactive. Bartonella henselae DNA was detected by species-specific nested polymerase chain reaction. After treatment, the patient progressed with no fever or lymphadenopathy. Bartonellosis is a group of infectious diseases caused by bacteria of the genus Bartonella. This case report is a useful reminder to clinicians that long-term fever of unknown origin can be related to B. henselae infection, even if the specific serology is not reactive.

Dengue and Chikungunya Co-Infection-Associated Multi-Organ Dysfunction Syndrome: A Case Report

“…Severe dengue virus infection symptoms are linked to an aggressive inflammatory response known as a cytokine storm, which is the concurrent production of large amounts of proinflammatory cytokines accompanied by abnormalities in the coagulation cascade, platelet dysfunction, impaired membrane permeability, and direct injury to the alveolar lining cells by DENV, ultimately causing the development of DAH [ 14 ]. The management of DAH in intubated patients includes the use of high PEEP and low TV (6 mL/kg/ideal body weight) for combating refractory hypoxemia, along with the administration of pulse methylprednisolone (1g IV OD) unless a non-immune cause of DAH is apparent [ 15 ].…”

Severe dengue in the intensive care unit

“…However, controlling liquid balance and avoiding fluid overload are crucial approaches to minimizing pleural effusion and pulmonary edema. Similar to the treatment of thrombocytopenic purpura, [ 151 ] the use of high-dose corticoids and immunoglobulin has been reported to be successful in literature, [ 152 ] although further studies are necessary to establish their effectiveness.…”