Severe dengue in the intensive care unit

Tejo, Alexandre Mestre; Hamasaki, Debora Toshie; Menezes, Letícia Mattos; Ho, Yeh-Li

doi:10.1016/j.jointm.2023.07.007

Cited by 3 publications

(9 citation statements)

References 210 publications

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“…6 Severe Dengue is defined by one or more of the findings: 1) shock or respiratory distress, 2) bleeding, and 3) severe organ damage. 2 , 3 , 5 , 6 Patients with secondary infections are at risk of severity. Several co-existing conditions increase the risk of Severe Dengue: pregnancy, diabetes, hypertension, extremes of age (< 1 year and > 60 years), hemolytic anemia, chronic renal or hepatic failure, asthma, chronic obstructive pulmonary disease, and use of anticoagulants.…”

Section: Clinical Manifestationsmentioning

confidence: 99%

“…Vigilance of glycemic levels and discontinuation of oral hypoglycemic agents are warranted in diabetic patients. 5 Statins should be interrupted during Dengue infection due to their potential to increase transaminases and creatine kinase levels. 5 …”

Section: Preoperative Evaluationmentioning

confidence: 99%

“… 5 Statins should be interrupted during Dengue infection due to their potential to increase transaminases and creatine kinase levels. 5 …”

Section: Preoperative Evaluationmentioning

confidence: 99%

“…Its causative agent is the Dengue virus (DENV), with four serotypes in humans (DENV 1-4). 1 , 2 , 3 , 4 , 5 , 6 The pathogenesis of Dengue initiates upon viral entry into the bloodstream, targeting and infecting key cells such as endothelial cells, macrophages, and monocytes. This provokes an immune response and release of a variety of inflammatory mediators.…”

mentioning

confidence: 99%

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Anesthesia and perioperative care management in patients with Dengue Fever: considerations and challenges

Carvalho,

Azi,

Leal

et al. 2024

Brazilian Journal of Anesthesiology (English Edition)

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Section: Clinical Manifestationsmentioning

confidence: 99%

Section: Preoperative Evaluationmentioning

confidence: 99%

“… 5 Statins should be interrupted during Dengue infection due to their potential to increase transaminases and creatine kinase levels. 5 …”

Section: Preoperative Evaluationmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Anesthesia and perioperative care management in patients with Dengue Fever: considerations and challenges

Carvalho,

Azi,

Leal

et al. 2024

Brazilian Journal of Anesthesiology (English Edition)

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“…The DENV has caused an estimated number of about 390 million infections globally and 500,000 cases of DHF/DSS annually, with 2.5 billion people at risk (4) .Over the years, the incidence and geographic distribution of DF has surged in many countries, particularly in those with tropical and sub-tropical climates. DENV has continuously increased in prevalence since the 1950's, making it the most common arthropod-borne viral disease worldwide currently, with the spread and circulation of multiple serotypes (5).…”

Section: Introductionmentioning

confidence: 99%

Molecular detection of Dengue virus from febrile patient cases in Ghana

Bonney,

Pratt,

Ofori

et al. 2024

Preprint

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Background Viral hemorrhagic fevers (VHFs) are any group of viral infectious diseases that interfere with the blood’s ability to clot. Viruses that cause these hemorrhagic fevers are found in a variety of hosts including bats, rodents or arthropods like mosquitoes and ticks. Most VHFs are characterized or identified as outbreaks which makes it difficult to monitor or predict. As a result of the danger these infectious pathogens pose, the Noguchi Memorial institute for Medical Research (NMIMR) as part of its mandate in providing high end molecular and genomic laboratory diagnostics in support of national public health programs runs a test for suspected VHFs collected from health facilities across the country. Methods This a cross-sectional study where suspected viral hemorrhagic fever patients were recruited between January 2022 to December 2023. During the period, 2586 suspected serum and plasma samples were transported under cold chain to the NMIMR for testing. These samples were subjected to molecular amplification with the Real time polymerase chain reaction assay for potential VHFs including yellow fever, Ebola/Marburg, Lassa fever and Dengue viruses. Results We detected Dengue virus RNA from eight patient samples and subtyped into serotypes 1, 2 and 3 respectively, using the Johnson B. W. et al., 2005 protocol. All DENV cases were resident in the Greater Accra region. Phylogenetic analysis revealed that the DENV-1 strain detected shared similarity with circulating strains in West Africa. Whole genome sequencing was conducted using Illumina Next Generation Sequencing Technology. Using IQ-TREE, a maximum likelihood phylogenetic analysis was carried out. Conclusion Until the emergence of recent cases, the circulating subtype has been serotyped Dengue two. With the detection of serotype one, it increases the possibility of multiple infections in individuals and may have worse or increased risk of severe dengue fever. There is therefore the need to intensify surveillance and also to control the mosquito vectors which can transmit these DENV in Ghana.

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A Narrative Review of Dengue Disaster in Bangladesh: Unprecedented Outbreak and Management Failure

Osail,

Sanny,

Zerin

2024

J Bacteriol Virol.

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Dengue has evolved into a significant global public health concern, particularly in tropical regions. This review focuses on Bangladesh's struggle with recurrent and severe dengue outbreaks. The country, located in Southeast Asia, is becoming more and more vulnerable to dengue due to climate change, high population density, and rapid urbanization. Dengue outbreaks have been unprecedentedly severe in the last 6 years. Dengue's seasonality in Bangladesh has expanded as well, with cases now reported throughout the year. Bangladesh faces challenges in managing dengue due to a strained healthcare system, underreporting, inadequate vector control, and insufficient public awareness. The ongoing political and financial crises further hinder effective dengue management. Urgent and comprehensive strategies are imperative to address this escalating public health crisis.

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Severe dengue in the intensive care unit

Cited by 3 publications

References 210 publications

Anesthesia and perioperative care management in patients with Dengue Fever: considerations and challenges

Anesthesia and perioperative care management in patients with Dengue Fever: considerations and challenges

Molecular detection of Dengue virus from febrile patient cases in Ghana

A Narrative Review of Dengue Disaster in Bangladesh: Unprecedented Outbreak and Management Failure

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