Pulmonary Function in Welders Exposed to Ozone

Young, W. A.; Shaw, Doug; Bates, David V.

doi:10.1080/00039896.1963.10663542

Cited by 14 publications

(1 citation statement)

References 5 publications

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“…An important observation was made in 1967 by Wayne and coworkers (12), who reported that the seasonal improvement in race times of high school cross-country runners was inversely related to the ambient ozone concentration. Although lung function and respiratory symptoms were not examined in this study, it was known that considerably higher concentrations of ozone could cause alterations in lung function in resting subjects (13)(14)(15). The importance of this study (12) was that it indicated that heavily exercising, healthy, young men could experience adverse effects at relatively low ozone levels commonly found in the ambient air.…”

Section: Ozonementioning

confidence: 96%

Human health effects of air pollution.

Folinsbee

1993

Environ Health Perspect

131

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Over the past three or four decades, there have been important advances in the understanding of the actions, exposure-response characteristics, and mechanisms of action of many common air pollutants. A multidisciplinary approach using epidemiology, animal toxicology, and controlled human exposure studies has contributed to the database. This review will emphasize studies of humans but will also draw on findings from the other disciplines. Air pollutants have been shown to cause responses ranging from reversible changes in respiratory symptoms and lung function, changes in airway reactivity and inflammation, structural remodeling of pulmonary airways, and impairment of pulmonary host defenses, to increased respiratory morbidity and mortality. Quantitative and qualitative understanding of the effects of a small group of air pollutants has advanced considerably, but the understanding is by no means complete, and the breadth of effects of all air pollutants is only partially understood.

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Section: Ozonementioning

confidence: 96%

Human health effects of air pollution.

Folinsbee

1993

Environ Health Perspect

131

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The Emergence of Controlled Human Exposure Studies

Bates

1993

Advances in Controlled Clinical Inhalation Studies

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Lung function and clinical findings in a cross-sectional study of arc welders

Mur

Teculescu

Pham

et al. 1985

Int. Arch Occup Environ Heath

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An epidemiological, cross-sectional study was conducted in order to assess non-neoplasic effects on the lung due to chronic exposure to arc welding fumes and gases. The study involved 346 arc welders and 214 control workers from a factory producing industrial vehicles. These workers (welders and controls) had never been exposed to asbestos. Respiratory impairments were evaluated by using a standardized questionnaire, a clinical examination, chest radiophotography and several lung function tests (spirometry, bronchial challenge test to acetylcholine, CO transfer tests according to the breath-holding and the steady-state methods, N2 washout test). The only significant differences between the welders overall compared to the controls were a slightly higher bronchial hyper-reactivity to acetylcholine and a lower lung diffusing capacity for CO in the welders. However, non-specific, radiologic abnormalities (reticulation, micronodulation) and obstructive signs were more frequent in the most exposed welders (welding inside tanks) than in welders working in well ventilated workplaces. The nature of the metal welded (mild-steel, stainless steel, aluminium) did not seem to have an influence on respiratory impairments. In the mild-steel welders, respiratory symptoms (dyspnoea, recurrent bronchitis) and obstructive signs were more frequent in the welders using a manual process than in the welders involved with the semi-automatic process (MIG). For all the workers (welders and controls), smoking had a markedly adverse effect on respiratory symptoms and lung function. Moreover, smoking seemed to interact with welding since CO lung transfer was more impaired in smoking welders than in smoking controls.

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Pulmonary Function in Welders Exposed to Ozone

Cited by 14 publications

References 5 publications

Human health effects of air pollution.

Human health effects of air pollution.

The Emergence of Controlled Human Exposure Studies

Lung function and clinical findings in a cross-sectional study of arc welders

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