Pulmonary embolism—a long-term follow-up

Abstract

Summary Fifty-three patients without pre-existing cardiac or pulmonary disease were reviewed 5 to 9 years after angiographically proved pulmonary embolism. Ten of the 42 (24%) with an initial predisposing factor for embolism had died, including 6 from a previously diagnosed medical condition. In this group there was no significant residual disability among survivors and no late recurrence of embolism. By comparison, there were 6 deaths among the 11 in whom no predisposing factor was identified (55%), including 3 from neoplasm and 2 from recurrent embolism with cardiac failure. The identification of a predisposing factor at the time of embolism was associated with a significantly better long-term prognosis.

Deep Vein Thrombosis and Occult Cancer

“…Among these, three were not known to have malignant disease when they presented with pulmonary embolism. More recently, Mclntyre et al have reviewed 53 patients 5-9 years after angiographically proved pulmonary embolism (16). Among the 11 patients presenting with apparently spontaneous thromboembolism, six died, and in three of them cancer was the cause of death.…”

Study of acute pulmonary embolism patients in Sohag University Hospital

“…(3) Other studies have reported that in patients without preexisting cardiac or pulmonary disease, the 1-year mortality rate ranged from 3% to 9%. (4,5) Mortality in APE is mainly reported to be due the associated comorbid conditions like cancer, infections, cardiovascular diseases, and other pulmonary diseases. (6) The varied clinical presentation of this condition makes the diagnosis challenging, treatment diverse and results unpredictable with subsequent high morbidity and mortality.…”

Acute pulmonary thromboembolism: Epidemiology, predictors, and long-term outcome – A single center experience

“…The 1-year mortality rate in the PIOPED study was reported as ≈25%, with 2.5% dying from primary cause as pulmonary embolism itself 3 . Other studies have reported that in patients without preexisting cardiac or pulmonary disease, the 1-year mortality rate ranged from 3% to 9% 4, 5. Mortality in APE is mainly reported to be due the associated comorbid conditions like cancer, infections, cardiovascular diseases, and other pulmonary diseases 6 …”