“…On top of a reduction in retinal illumination, it has been suggested that a unilateral cataract can also cause a spontaneous Pulfrich effect through retinal defocusing, i.e., blurring, which also slows retinocortical transmission and increases visual latency [23]. However, Cetinkaya et al [23,24] Corneal opacity [21] Iatrogenic, e.g., uniocular mydriasis, X-chrom lens [19] Traumatic anisocoria [21] Affecting neural conduction Post retinal detachment repair [21] Macular disease [26,27] Asymmetric pigmentary glaucoma [22] Central pathway conditions Optic neuritis/multiple sclerosis [21,[33][34][35][36][48][49][50] Mid-facial injuries [31,32] Other optic nerve pathologies [28][29][30]51] Pituitary tumours and temporoparietal astrocytomas [38] Anisometropic amblyopia [16] reported that the magnitude of the spontaneous Pulfrich effect in patients with unilateral cataracts did not correlate with visual acuity, but correlated with the presence of binocular symptoms [25]. Indeed, it has been suggested that the presence of the Pulfrich effect may account for visual symptoms in patients with unilateral cataracts that are independent of visual acuity, stereoacuity and contrast sensitivity [23].…”