PTH-174 Non-endoscopic screening for barrett’s oesophagus: identifying neoplasia with infrared spectroscopy

Old, OJ; Lloyd, Gavin R.; Almond, M.; Kendall, Catherine; Barr, Hugh; Shore, Angela C.; Stone, Nick

doi:10.1136/gutjnl-2015-309861.1062

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2016

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“…In the 93% of patients who were able to complete the test the cytosponge had a sensitivity of 87% and a specificity of 92% in diagnosing BO[47]. Obtaining cytology via a cytosponge also potentially allows for the identification of neoplasia using infrared microscopy but further studies are required[48]. …”

Section: Screeningmentioning

confidence: 99%

Evolving management of metaplasia and dysplasia in Barrett's epithelium

Evans

Mourad

Fisher

et al. 2016

WJG

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Oesophageal cancer affects more than 450000 people worldwide and despite continued medical advancements the incidence of oesophageal cancer is increasing. Oesophageal cancer has a 5 year survival of 15%-25% and now globally attempts are made to more aggressively diagnose and treat Barrett’s oesophagus the known precursor to invasive disease. Currently diagnosis the of Barrett’s oesophagus is predominantly made after endoscopic visualisation and histopathological confirmation. Minimally invasive techniques are being developed to improve the viability of screening programs. The management of Barrett’s oesophagus can vary greatly dependent on the presence and severity of dysplasia. There is no consensus between the major international medical societies to determine and agreed surveillance and intervention pathway. In this review we analysed the current literature to demonstrate the evolving management of metaplasia and dysplasia in Barrett’s epithelium.

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Section: Screeningmentioning

confidence: 99%