PTC Taste Sensitivity in Toxic Diffuse Goitre

Persson, I; Kølendorf, L.; Kølendorf, K

doi:10.1159/000152524

Cited by 5 publications

(2 citation statements)

References 4 publications

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“…There have been reports of associations or lack of associations between PTC taste status and diseases and traits not directly related to taste. These include diabetes (Terry and Segall 1947, Terry 1950, Akesson 1959b, Bayani-Sioson 1964, Schelling, Tetreault, Lasagna et al 1965, Rao and Sisodia 1970, Ali, Azad Khan, Mahtab et al 1994, dental caries (Chung, Witkop and Henry 1962), eye disease (Becker and Morton 1964, Suzuki, Takeuchi and Kitazawa 1966, Alsbirk and Alsbirk 1972, Kalmus and Lewkonia 1973, thyroid disorders (Harris, Kallmus and Trotter 1949, Kitchin, Howel-Evans, Clarke et al 1959, Shepard and Gartler 1960, Fraser 1961, Shepard 1961, Brand 1963, Hollingsworth 1963, Bayani-Sioson 1964, Azevedo, Krieger, Mi et al 1965a, Covarrubias, Barzelatto, Stevenson et al 1965, De Luca and Cramarossa 1965, Paolucci, Ferro-Luzzi, Modiano et al 1971, Mendez de Araujo, Salzano and Wolff 1972, Persson, Kolendorf and Kolendorf 1972, Facchini, Abbati and Campagnoni 1990, Haque 1990, Koertvelyessy and Crawford 1990, Facchini, Pettener, Rimondi et al 1997, schizophrenia (Freire-Maia, Karam, Mehl et al 1968, Schlosberg andBaruch 1992), gastrointestinal ulcers (Kaplan, Fischer, Glanville et al 1964, Stanchev, Tsonev and Minchev 1985, Li, McIntosh, Byth et al 1990), depression …”

Section: Ptc Taster Status and Diseasesmentioning

confidence: 99%

The genetics of phenylthiocarbamide perception

Guo

Reed

2001

Annals of Human Biology

262

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The ability to taste the bitter compound phenylthiocarbamide (PTC) and related chemicals is bimodal, and all human populations tested to date contain some people who can and some people who cannot taste PTC. Why this trait has been maintained in the population is uncertain but this polymorphism may influence food selection, nutritional status or thyroid metabolism. The gene product that gives rise to this phenotype is unknown, and its characterization would provide insight into the mechanism of bitter taste perception. Although this trait is often considered a simple Mendelian trait, i.e. one gene two alleles, a recent linkage study found a major locus on chromosome 5p15 and evidence for an additional locus on chromosome 7. The development of methods to identify these genes will provide a good stepping-stone between single-gene disorders and polygenic traits.

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Section: Ptc Taster Status and Diseasesmentioning

confidence: 99%

The genetics of phenylthiocarbamide perception

Guo

Reed

2001

Annals of Human Biology

262

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“…Once begun, zoster paresis peaks within hours or days, after which no further worsening occurs in terms of either exacerbation of existing weakness or spread to other muscles [3]. Zoster-induced motor deficit varies in severity from mild to very profound.…”

Section: Discussionmentioning

confidence: 99%

Monoparesis secondary to herpes zoster

Bilal¹,

Iqbal

O’Moore

et al. 2009

Ir J Med Sci

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We describe a 90-year-old woman with right upper limb monoparesis secondary to varicella zoster virus infection as a result of extensive inflammatory involvement of the entire brachial plexus at root level. To our knowledge, this is the first report of entire brachial plexus involvement in a living patient of such advanced age. Despite a delay in presentation and thus initiation of treatment, a favourable clinical response was observed.

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Abdominal-wall postherpetic pseudohernia

Oliveira

Filho

Ettinger

et al. 2006

Hernia

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Herpes zoster affects 10-20% of the general population. Motor complications sometimes occur in the segments corresponding to the involved sensory dermatomes causing abdominal wall pseudohernias. We present a case of a 57-year-old woman with herpes zoster characteristical rash following T11-T12 right dermatomes. Ten days after dermatologic manifestations onset, she had developed a protrusion at the abdominal wall on the right flank. The electroneuromyography confirmed axonal motor commitment, and morphological defects were ruled out by ultrasonography. The bulge totally disappeared after 4 months of observation. Postherpetic pseudohernia must be suspected when a patient develops signs and symptoms of motor dysfunction that coincide with or follow a herpes zoster eruption resulting in abdominal-wall herniation. A review of the literature concerning these extremely exceptional sequelae of herpes zoster is presented.

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PTC Taste Sensitivity in Toxic Diffuse Goitre

Abstract: PTC taste sensitivity in patients with toxic diffuse goitre shows a bimodal distribution as in normal persons. Compared with controls, a significant deficiency of extreme tasters andan overweight of medium tasters was demonstrated in toxic diffusegoitre.

Cited by 5 publications

References 4 publications

The genetics of phenylthiocarbamide perception

The genetics of phenylthiocarbamide perception

Monoparesis secondary to herpes zoster

Abdominal-wall postherpetic pseudohernia

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