Psychotropic medication non-adherence among patients with severe mental disorder attending at Bahir Dar Felege Hiwote Referral hospital, north west Ethiopia, 2017

Abstract

Objective Medication non-adherence is a major public health problem that has been called an “invisible epidemic”. Globally, non-adherence rates among patients with severe mental illness ranged between 30 and 65%. It greatly increases the risk of illness exacerbation and hospitalizations. However, there is a paucity of studies examining treatment non-adherence and its associated factors among patients with severe mental disorder. Therefore, this study was aimed at determining the magnitude of medication non-adherence and associated factors among patients with severe mental disorder. Results A total of 409 study subjects were participated making a response rate of 92%. The overall prevalence of medication non-adherence was found to be 55.2% (95%, CI; 49.9%, 60.2%). Study participants whose age group of (25–34) [AOR = 3.04 (95% CI 1.27, 7.29)], study subjects taking their medication twice per day [AOR = 4.60 (95% CI 2.25, 9.43)], no social support [AOR = 4.4 (95% CI 1.78, 11.08)] and no insight for their treatment [AOR = 5.88 (CI 2.08, 16.59)] were significantly associated with medication non-adherence. The result of this study showed that non-adherence among patients with severe mental disorder was found to be high. Psychiatry health care providers have to consider the frequency of medication become once per day, continual awareness creation among professionals and engaging significant others for good social support system and continual treatment alliance is strongly commended for adherence. Electronic supplementary material The online version of this article (10.1186/s13104-019-4126-2) contains supplementary material, which is available to authorized users.

Self-stigma and medication adherence among patients with mental illness treated at Jimma University Medical Center, Southwest Ethiopia

“…In our study finding, 55 (18.3%) had poor social supports whereas 39 (13.0%) of them had high social supports. A closely related finding was reported by Gebeyehu et al where 45.9% had good social support [29]. Living with kids and spouses was negatively associated with self-stigma up on multivariable linear regression.…”

“…Contrary to this, the prevalence was higher than in India 26% [ 58 ] and Addis Ababa, Ethiopia (26.5%) [ 42 ]. The finding was also lower than a study conducted in Nigeria (48.0%) [ 59 ], Curitiba, Parana (49%) [ 60 ], Nigeria 54.2% [ 61 ], Bahir Dar, Ethiopia (55.2%) [ 29 ], South Africa 63.2% [ 62 ] and Pakistan’s study (64.75%) [ 63 ]. This variation could be due to the differences in socio-demography of the study population, selection criteria for the study participants, study design, sample size and tools used for the assessment of adherence.…”

“…Additionally, cross-sectional facility-based study conducted in Addis Ababa, Ethiopia reported that nearly three-quarters of respondents (71%) expressed strong agreement to at least one internalized stigma item [42]. A study by Gebeyehu et al reported that (25.7%) of patients with severe mental disorders attending Bahir Dar Felege Hiwote Referral hospital had perceived stigma [29]. Additionally, study by Adewuya et al in Lagos, Nigeria reported that high self-stigma was found in 21.6% of the outpatients in the study [13].…”

“…Medication non-adherence is a major public health problem that has been called an “invisible epidemic” [ 29 ]. Researchers have indicated that self-stigma is one of the potentially important factors contributing to non-adherence to medication.…”

Quality of life and its association with current substance use, medication non-adherence and clinical factors of people with schizophrenia in Southwest Ethiopia: a hospital-based cross-sectional study

“…In our study, the 111(31.65%) of participants were non-adherent to their medication and this result was higher than study conducted at Ayder Referral Hospital, Mekelle, Northern Ethiopia which revealed 26.5% of patients with schizophrenia were non-adherent to their antipsychotic medication [29] and the result was lower than finding of the study conducted at Bahir Dar Felege Hiwote Referral hospital, northwest Ethiopia which revealed overall prevalence of medication non-adherence was 55.2% [30] This difference could be due to the different tools used to measure medication non-adherence. The lowest score on the social relationship domain of QoL among people with schizophrenia in our study could be due to the negative symptoms, which affect the patient's ability to live independently, to perform activities of daily living, to be socially active and maintain personal relationships.…”