Psychosocial impact of inclusion of HPV test on the management of women with atypical squamous cells of undetermined significance: a study within a randomised pragmatic trial in a middle-income country

Emotional response to testing positive for human papillomavirus at cervical cancer screening: a mixed method systematic review with meta-analysis

“…Seventeen papers were quantitative studies (Alay et al, 2019;Andreassen et al, 2019;Ferenidou et al, 2012;Garces-Palacio et al, 2019;Hsu et al, 2018;Kitchener et al, 2008;Kwan et al, 2011;Maggino et al, 2007;Maissi et al, 2004Maissi et al, , 2005McBride et al, 2020;McCaffery et al, 2004;Nagele et al, 2019;Ngu et al, 2018;Rodriguez et al, 2019;Wang et al, 2010;Wang et al, 2011), 15 were qualitative (Barrera-Clavijo et al, 2015;Barreto et al, 2016;Bertram & Magnussen, 2008;Head et al, 2017;Kosenko et al, 2012;Lin et al, 2011;Linde et al, 2019;McCaffery & Irwig, 2005;McCaffery et al, 2006;McCurdy et al, 2011;O'Connor et al, 2014;Perrin et al, 2006;Tiro et al (2019); Waller, McCaffery, et al, 2007;Wyndham-West et al, 2018) and one was mixed-methods (Daley et al, 2010). A total of 12,789 women aged between 18 and 65 participated in twenty studies (n=12,244 quantitative; n=545 qualitative), of whom 4,305 were reported as having tested positive for HPV (n=3,874 quantitative; n=431 qualitative).…”

“…Observational (cross-sectional, prospective longitudinal, or cohort) designs were used in most quantitative studies (thirteen out of seventeen). Four quantitative studies used a randomised controlled design (Garces-Palacio et al, 2019;Kitchener et al, 2008;Maggino et al, 2007;Ngu et al, 2018), but only one directly tested and reported differences in emotion between result groups (Kitchener et al, 2008). The same RCT study also included additional analyses on the observational findings from women in the study arm where participants were informed about their HPV results.…”

“…Ten quantitative studies measured anxiety at different time points (Alay et al, 2019;Garces-Palacio et al, 2019;Kitchener et al, 2008;Kwan et al, 2011;Maggino et al, 2007;Maissi et al, 2004Maissi et al, , 2005McBride et al, 2020;McCaffery et al, 2004;Ngu et al, 2018) mostly using the state subscale from the state-trait anxiety inventory (Marteau & Bekker, 1992;Spielberger, 1983).…”

“…Sixteen quantitative studies included a measure of psychological distress: ten included test-specific distress (Ferenidou et al, 2012;Garces-Palacio et al, 2019;Kwan et al, 2011;Maissi et al, 2004Maissi et al, , 2005McBride et al, 2020;McCaffery et al, 2004;Ngu et al, 2018;Wang et al, 2010Wang et al, , 2011, eleven sexual distress (Alay et al, 2019;Ferenidou et al, 2012;Hsu et al, 2018;Kitchener et al, 2008;Kwan et al, 2011;Maggino et al, 2007;Maissi et al, 2005;McCaffery et al, 2004;Nagele et al, 2019;Wang et al, 2010Wang et al, , 2011 and six general distress (Andreassen et al, 2019;Hsu et al, 2018;Kitchener et al, 2008;Maissi et al, 2004Maissi et al, , 2005McBride et al, 2020). Test-specific distress was consistently higher (worse) for women testing HPV-positive with any cytology result compared to normal results up to 6-months post-result (Maissi et al, 2005), but not at 12-months post-result (Garces-Palacio et al, 2019).…”

Utility of Scoring System for Screening and Early Warning of Cervical Cancer Based on Big Data Analysis

“…In 2014, HPV DNA typing assay was introduced to China as an initial screening method for cervical cancer, but HPV test cannot determine the specific disease type and single diagnosis has low sensitivity and poor specificity, also, TCT alone has a high rate of missed diagnoses. In addition, with China's large population base and limited health resources, the key point of cervical cancer screening is to develop specific screening programs and select appropriate screening methods ( 16 , 17 ).…”