“…A review by Siegrist and Marmot discusses psychosocial variables as causative, aggravating, and perpetuating factors for the stress response, as well as stress implicating elevated psychosocial variables [ 146 ]. The stress response has been associated with the propagation of numerous disorders including: dermatological [ 147 ], cardiovascular [ 148 , 149 ], diabetic [ 150 ], Hepatic [ 151 ], immune [ 152 ], thyroid [ 153 ], gastrointestinal [ 154 , 155 ], reproductive [ 156 - 158 ], renal [ 159 ], metabolic [ 160 ], rheumatic [ 161 ] and musculoskeletal [ 162 , 163 ].…”