Psychophysiology of visceral pain in IBS and health

Haüser, Winfried; Langhorst, Jost; Dobos, Gustav; Enck, Paul

doi:10.1016/j.jpsychores.2008.02.024

Cited by 22 publications

(14 citation statements)

References 75 publications

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“…As stress can result in overactivity or underactivity along the hypothalamic-pituitary-adrenal (HPA) axis and of the autonomic nervous (ANS), metabolic, and immune systems, it can alter brain-gut interactions, ultimately affecting different physiological functions of the gastrointestinal tract [7] . The relationship between psychological stress and visceral hypersensitivity has been studied and well described by Musial et al [8] and Larauche et al [9] , so this review will not cover that aspect of this topic. The purposes of this review are (1) to provide an overview of how psychological stress contributes to the development of IBS and aggravation of IBS symptoms; and (2) to inform a more comprehensive approach to the management of IBS.…”

Section: Impact Of Psychological Stress On Irritable Bowel Syndromementioning

confidence: 99%

Impact of psychological stress on irritable bowel syndrome

Qin

Cheng

Tang

et al. 2014

WJG

273

195

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Psychological stress is an important factor for the development of irritable bowel syndrome (IBS). More and more clinical and experimental evidence showed that IBS is a combination of irritable bowel and irritable brain. In the present review we discuss the potential role of psychological stress in the pathogenesis of IBS and provide comprehensive approaches in clinical treatment. Evidence from clinical and experimental studies showed that psychological stresses have marked impact on intestinal sensitivity, motility, secretion and permeability, and the underlying mechanism has a close correlation with mucosal immune activation, alterations in central nervous system, peripheral neurons and gastrointestinal microbiota. Stress-induced alterations in neuro-endocrine-immune pathways acts on the gut-brain axis and microbiota-gut-brain axis, and cause symptom flare-ups or exaggeration in IBS. IBS is a stress-sensitive disorder, therefore, the treatment of IBS should focus on managing stress and stress-induced responses. Now, non-pharmacological approaches and pharmacological strategies that target on stress-related alterations, such as antidepressants, antipsychotics, miscellaneous agents, 5-HT synthesis inhibitors, selective 5-HT reuptake inhibitors, and specific 5-HT receptor antagonists or agonists have shown a critical role in IBS management. A integrative approach for IBS management is a necessary.

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Section: Impact Of Psychological Stress On Irritable Bowel Syndromementioning

confidence: 99%

Impact of psychological stress on irritable bowel syndrome

Qin

Cheng

Tang

et al. 2014

WJG

273

195

View full text Add to dashboard Cite

show abstract

“…Chronic pain conditions of the back, such as lumbago and/or neck pain, play a prominent role in clinical practice and are essentially characterized by muscle pain and thus relate to deep somatic origin. Like visceral pain [1], deep somatic pain is dull, difficult to localize [2], and difficult to treat. Chronic pain conditions affecting the neck and lower back are clinically highly relevant [3,4,5,6,7,8]: The lifetime prevalence for neck pain is approximately 48-66% and for lower back pain 51-84%.…”

Section: Clinical Backgroundmentioning

confidence: 99%

Naturopathic Reflex Therapies for the Treatment of Chronic Back and Neck Pain - Part 1: Neurobiological Foundations

Musial

Spohn²,

Rolke³

2013

Complement Med Res

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Evidence from recent RCT's has shown that naturopathic reflex therapies such as massage, Gua Sha massage, cupping, wet packs, or rhythmic embrocation etc. are helpful in reducing symptoms of chronic pain. These bodily oriented therapies are likely able to influence chronic pain not only through brain mechanisms such as expectation or the feeling of well-being, but also through mechanisms at the level of the peripheral nociceptor and the spinal cord. However, the neurobiological basis of these effects has rarely been investigated even though the accumulating knowledge of the pathophysiology of chronic pain syndromes allows for developing specific hypotheses. This essay discusses specific reflex therapies (cupping, Gua Sha massage, classical massage, and rhythmic embrocation) and their possible mechanisms of action via ascending pathways to the brain.

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“…In addition, visceral pain is usually associated with autonomic reactions such as sweating and nausea. Consequently, it should be acknowledged, that visceral pain is a priori processed in the affectiveemotional pain processing system, most likely without an appreciable, sensory-discriminative component [19].…”

Section: From Nociception To Painmentioning

confidence: 99%

Functional Chronic Pain Syndromes and Naturopathic Treatments: Neurobiological Foundations

Musial¹,

Michalsen²,

Dobos³

2008

Forsch Komplementärmed

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There is increasing clinical evidence that reflex therapies such as massage, Gua Sha, cupping, wet packs, acupuncture etc. are helpful in reducing symptoms of chronic pain. However, the neurobiological basis of these effects has rarely been investigated even though the increasing knowledge of the pathophysiology of chronic pain syndromes allows for specific hypotheses. Reflex therapies are likely able to influence chronic pain at the level of the nociceptor and the spinal cord. Moreover, it can be speculated that these therapies have a strong impact on relaxation and maybe understood as a social, comforting interaction. Since it is well accepted that the positive effect of grooming has a neurobiological basis in non-human primates, its biosocial impact on wellbeing and pain processing in humans may be underestimated. A synopsis of the neurobiological foundations of pain perception, from the nociceptor up the spinal cord to brain mechanisms provides the basis for the investigation of the ‘way of action’ of reflex therapies. Specific hypotheses on their neurobiological bases and methods suitable for their investigation are outlined. Further clarification of the mechanisms of action of reflex therapies will support their clinical evidence and add to our understanding of the neurobiology of complementary medicine.

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Psychophysiology of visceral pain in IBS and health

Cited by 22 publications

References 75 publications

Impact of psychological stress on irritable bowel syndrome

Impact of psychological stress on irritable bowel syndrome

Naturopathic Reflex Therapies for the Treatment of Chronic Back and Neck Pain - Part 1: Neurobiological Foundations

Functional Chronic Pain Syndromes and Naturopathic Treatments: Neurobiological Foundations

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