Psychophysiological Concomitants of Organizational Change in Health Care Personnel: Effects of a Controlled Intervention Study

Lökk, Johan; Arnetz, Bengt B.

doi:10.1159/000289111

Cited by 26 publications

(8 citation statements)

References 10 publications

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“…Modalities associated with decreased levels seem to have in common that they increase arousal levels. Rising plasma prolactin concentration has been observed mainly during real-life situations characterized as uncontrollable and depressing or causing withdrawal [19, 20]. In the present study, decreasing levels were seen before the stress interview and increasing levels during the interview in both groups.…”

Section: Discussionsupporting

confidence: 51%

Low Plasma Prolactin Levels in Patients with Functional Dyspepsia

Jonsson

Theorell²

1999

Psychother Psychosom

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Background: The purpose was to compare the levels and patterns of plasma cortisol and prolactin in patients with functional dyspepsia (FD) during a controlled laboratory experiment. Method: 25 patients (12 men, 13 women), aged 24–50, with recurrent FD, and 25 pair-wise gender- and age-matched community control subjects were studied at a gastroenterological laboratory in a Swedish university hospital. In an experiment, after a rest period, subjects were studied during a neutral interview and a stress interview. Before and during interventions, blood samples were drawn for later peptide analyses. The main outcome measures were the Gastrointestinal Symptom Rating Scale, heart rate, blood pressure, plasma cortisol and prolactin. Results: Mean plasma cortisol concentration correlated negatively with diarrhoea symptoms (partial correlation; p < 0.01). The level of plasma proclatin (µg/l) was significantly lower (paired t test; p < 0.01) in the patient group (mean = 3.34, CI: 2.75–3.93) compared to the control group (mean = 4.70, CI: 3.63–5.78). During the stress interview, prolactin increased significantly in both groups. When the whole sample was divided according to degree of reflux symptoms, those with high reflux symptomatology had lower prolactin (ANCOVA with covariates for group, gender, age, body mass index and smoking; p < 0.05). Conclusion: Plasma prolactin concentration was significantly lower in FD patients compared to a matched control group. A high degree of reflux symptoms was significantly associated with inhibition of the prolactin increase during a stress interview.

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Section: Discussionsupporting

confidence: 51%

Low Plasma Prolactin Levels in Patients with Functional Dyspepsia

Jonsson

Theorell²

1999

Psychother Psychosom

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“…The results of an intervention study indicate that an involvement and interest in improving the work organization may buffer a stress response related to organizational changes [21]. Another intervention study showed an association between a psychosocial empowerment programme and decreasing prolactin levels [22]. Hence, successful coping may prevent endocrine disturbances in stressful conditions, for instance an increase in prolactin [13]and a decrease in testosterone [12].…”

Section: Discussionmentioning

confidence: 99%

Stress Markers in Relation to Job Strain in Human Service Organizations

Ohlson¹,

Söderfeldt²,

Söderfeldt

et al. 2001

Psychother Psychosom

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Background: Workers in human service organizations are often confronted with conflicting demands in providing care or education. The aim of this cross-sectional study was to relate levels of endocrine stress markers to perceived job strain in two human service organizations. Methods: Employees in two local units of the social insurance organization and two local units of the individual and family care sections of the social welfare in Sweden were selected and 103 employees participated (56% participation rate). The perceived job strain was assessed with a standardized questionnaire containing questions of the demand-control model. Questions specially designed to measure emotional demands were also included. The stress markers cortisol, prolactin, thyroid-stimulating hormone, testosterone and IgA and IgG were analysed in blood samples. Results: The main finding was an association between high emotional strain and increased levels of prolactin. The levels of cortisol, but none of the other four stress markers, increased slightly with emotional strain. Conclusions: Emotional strain experienced in human service work may cause psychological stress. The increase in prolactin was modest but consistent with findings in other published studies on stress-related endocrine alterations.

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“…All three of the clusterrandomized trials (31-33) had a unit of analysis error; in other words, they analyzed the results at the individual level without taking the effect of the cluster design into account. The reasons for excluding nine studies from the meta-analyses were unique interventions like recreational music-making (34), therapeutic massage (35), support and advice from a psychologist (31,36), and "primary nursing" (37), or insufficient reporting of outcome data (33,(38)(39)(40)(41).…”

Section: Methodsmentioning

confidence: 99%