Psychopathy as a disorder of the moral brain: Fronto-temporo-limbic grey matter reductions demonstrated by voxel-based morphometry

Oliveira‐Souza, Ricardo de; Hare, Robert D.; Bramati, Ivanei E.; Garrido, Griselda J.; Ignácio, Fátima Azevedo; Tovar‐Moll, Fernanda; Moll, Jorge

doi:10.1016/j.neuroimage.2007.12.054

Cited by 222 publications

(186 citation statements)

References 63 publications

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“…The reduced volume of the lateral and ventral PFC was found in "unsuccessful" psychopaths (Yang et al, 2005). In a separate study, reduced cortical thickness in psychopathic adult males was found (Yang et al, 2009). De Oliveira-Souza et al (2008 found the reduced GM volume in the frontopolar cortex with the area of the vmPFC and orbitofrontal cortex.…”

Section: Resultsmentioning

confidence: 84%

Dysfunctional Love in Psychopathic Criminals: The Neural Basis

Gawda

2012

Neuroquantology

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This study focused on the description of love by individuals diagnosed with psychopathy and antisocial personality disorder (ASPD). The aim of the study was to test the hypothesis that psychopathic individuals have ambiguous, ambivalent, and dysfunctional representation of love, which is expressed in their emotional language. The study participants consisted of 60 prison inmates with ASPD, 40 prison inmates without ASPD, and 60 men without antisocial tendencies who described situations involving love. The descriptions of love expressed in the narratives were analyzed, and a comparison of the three groups revealed differences between inmates with psychopathy and ASPD, inmates without psychopathy and ASPD, and the control group. The psychopathic individuals described love as an unclear complex emotion, strong, and with and inappropriate valence and high self-concentration. The description of love showed the lack of clear understanding of the situation of love, people involved in this situation, and the results. This dysfunctional form of love presented by individuals with psychopathy has been discussed in terms of their neurobiological deficits related to the prefrontal cortex, temporal lobes, amygdala, grey matter structure, and limbic abnormalities.

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Section: Resultsmentioning

confidence: 84%

Dysfunctional Love in Psychopathic Criminals: The Neural Basis

Gawda

2012

Neuroquantology

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“…This evidence ties in with previous structural and functional findings investigating self-transcendent-related behaviors and deficits. For example, in a VBM study (de Oliveira-Souza et al, 2008), psychopathic patients (i.e., individuals with moral deficits) showed reduced GM in a number of regions including OFC. In addition, Hare, Camerer, Knoepfle and Rangel (2010) found that higher medial orbitofrotnal cortex (ventromedial prefrontal cortex) activity was associated with the higher subjective liking of donations at the time of the decision-making.…”

Section: Discussionmentioning

confidence: 99%

Nonlinear associations between human values and neuroanatomy

Zacharopoulos

Hanel

Lancaster

et al. 2016

Social Neuroscience

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“…Experience sharing is the tendency to take on, resonate with, or ''share'' the emotions of others, and it is often tied to a mechanism known as ''neural resonance.'' 10 Several neuropsychiatric disorders, including schizophrenia, 13,20,21 autism spectrum disorders, 11,[22][23][24][25] psychopathy, 26 brain injury, 27 and frontotemporal lobe degeneration, 28 feature different subprocesses of empathy deficits. 13 Accordingly, assessment of the recognition and processing of emotion in individuals with OCD would provide a more comprehensive evaluation of these subjects and could explain many social and interpersonal aspects of their disease.…”

Section: Introductionmentioning

confidence: 99%

Two systems for empathy in obsessive-compulsive disorder: mentalizing and experience sharing

Pino

Berardis²,

Mariano

et al. 2016

Rev. Bras. Psiquiatr.

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Objective: To investigate empathic abilities in patients with obsessive-compulsive disorder (OCD) compared to control subjects. OCD is characterized by persistent obsessions and compulsions. Previous studies have proposed specific emotion recognition deficits in patients with OCD. The ability to recognize emotion is part of the broad construct of empathy that incorporates mentalizing and experience-sharing dimensions. Methods: Twenty-four subjects with a diagnosis of OCD and 23 control subjects underwent empathic measures. Results: Patients with OCD compared to control subjects showed deficits in all mentalizing measures. They were incapable of understanding the mental and emotional states of other people. On the other hand, in the sharing experience measures, the OCD group was able to empathize with the emotional experience of other people when they expressed emotions with positive valence, but were not able to do when the emotional valence was negative. Conclusion: Our results suggest that patients with OCD show a difficulty in mentalizing ability, whereas the deficit in sharing ability is specific for the negative emotional valence.

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Psychopathy as a disorder of the moral brain: Fronto-temporo-limbic grey matter reductions demonstrated by voxel-based morphometry

Cited by 222 publications

References 63 publications

Dysfunctional Love in Psychopathic Criminals: The Neural Basis

Dysfunctional Love in Psychopathic Criminals: The Neural Basis

Nonlinear associations between human values and neuroanatomy

Two systems for empathy in obsessive-compulsive disorder: mentalizing and experience sharing

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