Psychometric Properties and Factor Structures of the Korean Version of Children's Depression Rating Scale-Revised

Yoo

et al. 2020

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Literature suggests that neurobiological factors such as brain structure play an important role in linking social stress with depression in adolescence. We aimed to examine the role of subcortical volumetric alteration in the association between peer problems as one type of social stress and adolescent depression. We hypothesized that there would be indirect effects of peer problems on adolescent depression through subcortical volumetric alteration. Seventy eight adolescents with major depressive disorder (MDD) (age mean [SD] = 14.9 ± 1.5, 56 girls) and 47 healthy controls [14.3 ± 1.4, 26 girls]) participated in this study. High-resolution structural T1 images were collected using the Siemens 3T MR scanner. Subcortical volumes were segmented using the Freesurfer 6.0 package. Peer problems were assessed using the Peer-Victimization Scale and the Bullying-Behavior Scale. There was a significant indirect effect of peer problems on adolescent depression through nucleus accumbens (NAcc) volume alteration, but not through the amygdala and hippocampal volumes. This result supported our model, which stated that peer problems have indirect effects through subcortical volumetric alteration (i.e., increased NAcc volume) on adolescent depression. Our finding suggests that altered NAcc volume may serve as a pathway, through which peer problems as one type of social stressor contribute to adolescent depression. Adolescents experience peer problems (e.g., involvement in bully-victim problems) as they devote more time and effort to peer relationships 1. The mean prevalence rates of traditional bullying and cyberbullying involvement were approximately 35% and 15% across 80 studies 2. These peer problems such as being a bully and a victim are considered to be major social stressors, which are known to be related to important adolescent public health issues 3. For example, youth who were bullies and victims showed higher rates of concurrent depression 3 and reported to having long-term adverse effects with greater rates of adulthood depression and suicidality 4. A recent study showed that the prevalence rates of both peer problems and depression remained high in 2015, or even increased compared to those in 2005 5 , indicating that the associations between peer problems and adolescent depression may continue to affect significant public health problems. To ameliorate such public health problems associated with peer relational problems and adolescent depression, other factors should be considered. It has been suggested that neurobiological factors (e.g., brain structure and function) 6 may play an important role in linking social stress with adolescent depression. Furthermore, adolescence is a developmental period for remodeling brain structures and increasing neural plasticity in response to social stress 7. Brain structure may dramatically change in order to adapt to different social and emotional stresses (e.g., problematic peer relations such as bullying involvement) that frequently occur during adolescence. Brain structure alter...

Section: Clinical Assessments and Self-report Measures The Participamentioning

confidence: 95%

The indirect effect of peer problems on adolescent depression through nucleus accumbens volume alteration

Yoo

et al. 2020

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Journal of the American Academy of Child & Adolescent Psych

“…18 As no acceptable "gold-standard" for quantifying depression symptom severity in adolescents was identified by the review team, criterion validity was not considered evaluable for the CDRS-R, and as recommended, 18 the single study that reported evaluating "criterion validity" was included as an evaluation of construct validity. 27 Three reviewers (ES, SM, MO) independently recorded which of these nine measurement properties each study assessed according to COSMIN's measurement properties definitions.…”

Section: Measurement Propertiesmentioning

confidence: 99%

Systematic Review: The Measurement Properties of the Children’s Depression Rating Scale−Revised in Adolescents With Major Depressive Disorder

Stallwood

Monsour

Rodrigues

et al. 2021

Revised in adolescents with major depressive disorderThis research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors for the conduct of the research and/or preparation of the article. This article has been published in Stallwood et al. (2021). Systematic review: The measurement properties of the Children's Depression Rating Scale-Revised in adolescents with major depressive disorder.

“…These three items are rated based on the interviewer's observation only. In this study, we used the Korean version of the CDRS-R, which showed high internal consistency (a = 0.91) and strong criterion and discriminant validity (Kim et al 2017). A total score of 40 or higher on the Korean version of the CDRS-R indicates the presence of depressive disorder.…”

Section: Symptom Measuresmentioning

confidence: 99%

Effects of Antidepressant Treatment on Symptom Measures of Attention in Adolescents with Depression: A Preliminary Open-Label Study

Choi

Journal of Child and Adolescent Psychopharmacology

et al. 2021

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Objective: The effects of selective serotonin reuptake inhibitor (SSRI) on deficits in attention and executive function in adolescents with major depressive disorder (MDD) are relatively unknown. We aimed to investigate changes in symptom measures of attention in adolescents with MDD treated with escitalopram. Methods: The study included 82 MDD adolescents and 54 healthy controls aged from 12 to 17 years. Symptom measures of attention were assessed using the Attention-Deficit/Hyperactivity Disorder Rating Scale (ADHD-RS) and Child Behavior Checklist attention problems scale at baseline and during week 8. Adolescents who showed at least 40% improvement in the Children's Depression Rating Scale-Revised (CDRS-R) scores from baseline to week 8 were referred to as ''responders.'' Results: No baseline differences were found between the responders (n = 47) and nonresponders (n = 35) in their age, sex, intelligence quotient, CDRS-R score, and attention measures. Linear mixed models showed significant group-by-time interaction effect in the ADHD-RS inattention subscale score, but not in the other attention measures. Conclusion: Our results suggest that treating depressive symptoms with SSRI may lead to improvements in attention in MDD adolescents. Monitoring changes in symptom measures of attention can be useful when treating adolescents with MDD. ClinicalTrials.gov identifier: NCT03547219.