Psychometric evaluation of radio electric auricular treatment for stress-related disorders: A double-blinded, placebo-controlled controlled pilot study

Rinaldi, S.; Fontani, V.; Aravagli, L.; Bini, S.; Mannu, P.; Castagna, A.; Margotti, M. L.

doi:10.1037/e572992012-468

Cited by 3 publications

(4 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To expose mouse R1 ES cells to Wi-Fi RF energy, we used a REAC apparatus that was originally designed to use the effects produced by the interaction between the electromagnetic field of the human body (27) and that produced by the instrument working with typical range frequencies of 2.4, 5.7, or 10.5 GHz, selectable by operator. REAC stimulation has previously been shown to be efficacious in ameliorating stress-related depression and anxiety (3,14,21–23).…”

Section: Resultsmentioning

confidence: 99%

Radiofrequency Energy Loop Primes Cardiac, Neuronal, and Skeletal Muscle Differentiation in Mouse Embryonic Stem Cells: A New Tool for Improving Tissue Regeneration

et al. 2012

View full text Add to dashboard Cite

Radiofrequency (RF) waves from Wi-Fi (wireless fidelity) technologies have become ubiquitous, with Internet access spreading into homes, and public areas. The human body harbors multipotent stem cells with various grading of potentiality. Whether stem cells may be affected by Wi-Fi RF energy remains unknown. We exposed mouse embryonic stem (ES) cells to a Radio Electric Asymmetric Conveyer (REAC), an innovative device delivering Wi-Fi RF of 2.4 GHz with its conveyer electrodes immersed into the culture medium. Cell responses were investigated by real-time PCR, Western blot, and confocal microscopy. Single RF burst duration, radiated power, electric and magnetic fields, specific absorption rate, and current density in culture medium were monitored. REAC stimulation primed transcription of genes involved in cardiac (GATA4, Nkx-2.5, and prodynorphin), skeletal muscle (myoD) and neuronal (neurogenin1) commitment, while downregulating the self renewal/pluripotency-associated genes Sox2, Oct4, and Nanog. REAC exposure enhanced the expression of cardiac, skeletal, and neuronal lineage-restricted marker proteins. The number of spontaneously beating ES-derived myocardial cells was also increased. In conclusion, REAC stimulation provided a "physical milieu" optimizing stem cell expression of pluripotentiality and the attainment of three major target lineages for regenerative medicine, without using chemical agonists or vector-mediated gene delivery.

show abstract

Section: Resultsmentioning

confidence: 99%

Radiofrequency Energy Loop Primes Cardiac, Neuronal, and Skeletal Muscle Differentiation in Mouse Embryonic Stem Cells: A New Tool for Improving Tissue Regeneration

et al. 2012

View full text Add to dashboard Cite

show abstract

“…In Rinaldi et al [22] it was found that REAC can be an alternative therapy for stress-related disorders. Based on the randomized control study, 150 people in the group treated with REAC found a significant reduction in Psychological Stress Measure (PSM) scores, compared to 50 people in the control group who received a placebo.…”

Section: Reac Efficacy On Stressmentioning

confidence: 99%

“…In addition, REAC also optimizes the response to stressors so that it can cause a decrease in dysfunctional adaptive behavior [15]. In addition, REAC is also known to be an effective instrument for improving responses to allostatic conditions and environmental stressors [22].…”

Section: Reac Efficacy On Stressmentioning

confidence: 99%

Review: Radio Electric Asymmetric Conveyer (REAC) as adjuvant therapy of mental disorder

Ahadini¹,

Utama²,

Reihan³

et al. 2022

World J. Adv. Res. Rev.

View full text Add to dashboard Cite

Mental disorders are one of the health disorders that contribute to high rates of disability and mortality worldwide. The current therapeutic modalities used to treat mental disorders are medical and psychological approaches, but it becomes problematic in some conditions, such as drug-resistant mental disorders. Radio Electric Asymmetric Conveyer (REAC) technology can be used as an alternative to overcome this problem. This technology uses radio waves which are guaranteed to be non-invasive and do not cause side effects. This technology enables neuromodulation effects by maximizing cell polarity and optimizing endogenous bioelectric activity. Of course, the REAC's mechanism as a neuromodulator and being a non-invasive technology is safe to use. It allows REAC to be used as an adjuvant therapy to reduce symptoms of several mental disorders such as depression, anxiety, bipolar disorder, phobias, and stress.

show abstract

“…We can use auricular electroacupuncture, which is less invasive, of less cost, and convenient to treat diseases by setting up suitable parameters. Recently, kinds of acupuncture treatment instruments such as radio electric stimulator device [ 43 ] and P-Stim auricular electroacupuncture stimulation device [ 44 ] have been developed for the treatment of stress-related disorders and pain relief. Auricular vagal nerve stimulator is expected to be explored.…”

Section: Potential Application Of Auricular Acupuncture For Other mentioning

confidence: 99%

Auricular Acupuncture May Suppress Epileptic Seizures via Activating the Parasympathetic Nervous System: A Hypothesis Based on Innovative Methods

Rong

et al. 2012

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

Auricular acupuncture is a diagnostic and treatment system based on normalizing the body's dysfunction. An increasing number of studies have demonstrated that auricular acupuncture has a significant effect on inducing parasympathetic tone. Epilepsy is a neurological disorder consisting of recurrent seizures resulting from excessive, uncontrolled electrical activity in the brain. Autonomic imbalance demonstrating an increased sympathetic activity and a reduced parasympathetic activation is involved in the development and progress of epileptic seizures. Activation of the parasympathetic nervous system such as vagus nerve stimulation has been used for the treatment of intractable epilepsy. Here, we propose that auricular acupuncture may suppress epileptic seizures via activating the parasympathetic nervous system.

show abstract

Psychometric evaluation of radio electric auricular treatment for stress-related disorders: A double-blinded, placebo-controlled controlled pilot study

Abstract: Background: The aim of this double-blind randomized study is to test the efficacy of a radio electric stimulator device using an auricular reflex therapy protocol for stress-related symptoms.

Cited by 3 publications

References 33 publications

Radiofrequency Energy Loop Primes Cardiac, Neuronal, and Skeletal Muscle Differentiation in Mouse Embryonic Stem Cells: A New Tool for Improving Tissue Regeneration

Radiofrequency Energy Loop Primes Cardiac, Neuronal, and Skeletal Muscle Differentiation in Mouse Embryonic Stem Cells: A New Tool for Improving Tissue Regeneration

Review: Radio Electric Asymmetric Conveyer (REAC) as adjuvant therapy of mental disorder

Auricular Acupuncture May Suppress Epileptic Seizures via Activating the Parasympathetic Nervous System: A Hypothesis Based on Innovative Methods

Contact Info

Product

Resources

About