Psychological rehabilitation after myocardial infarction: multicentre randomised controlled trial

Jones, Dee; West, Robert

doi:10.1136/bmj.313.7071.1517

Cited by 246 publications

(133 citation statements)

References 21 publications

(30 reference statements)

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“…Although data are mixed from observational and smaller randomized studies, large randomized studies in other medical populations, most notably cardiology, have failed to demonstrate any improvement in survival or clinical outcomes with psychosocial screening and intervention programs. 27,[43][44][45][46][47][48][49][50][51][52][53][54] However, HSCT patients, most of whom face a higher probability of death and disability than the other populations studied, may form a particularly at risk group Table 4 Differences between distressed and not distressed subjects among subjects screened at the first clinic visit or 100 days post transplant (N ¼ 55) Table 5 Summary of pre-and post transplantation assessments from all enrolled subjects (N ¼ 80)…”

Section: Discussionmentioning

confidence: 99%

Routine screening for psychosocial distress following hematopoietic stem cell transplantation

Lee

Loberiza

Antin

et al. 2004

Bone Marrow Transplant

130

135

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Summary:The diagnosis and treatment of cancer is often associated with high levels of psychosocial distress, yet exploration of these issues is rarely included in routine oncologic care. We conducted a pilot study to evaluate the feasibility of screening for psychosocial distress after autologous and allogeneic stem cell transplantation. A total of 80 adults were enrolled in Boston, MA, USA. Subjects completed selfadministered assessments prior to hospital admission, at their first clinic visit after hospital discharge, and at 100 days post transplant. Assessments included validated instruments assessing psychosocial distress and quality of life (QOL). Elevated levels of anxiety and/or depression were detected in 55% of those providing pre-transplant assessments and were associated with compromised QOL. Post transplant screening was successfully performed in 69% of subjects and identified that 44% had symptoms of depression, anxiety or post traumatic stress disorder. Pretransplant distress was associated with detection of distress after transplantation (81 vs 13%, Po0.0001). In summary, we detected high levels of distress in transplant patients using self-administered tools. Pre-transplant distress appears to be highly predictive of distress post transplant and is a feasible marker to target screening and intervention programs.

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Section: Discussionmentioning

confidence: 99%

Routine screening for psychosocial distress following hematopoietic stem cell transplantation

Lee

Loberiza

Antin

et al. 2004

Bone Marrow Transplant

130

135

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“…A second large and well-controlled trial of stress management for post-MI patients also found no effects on cardiac recurrences (Jones & West, 1996). However, Blumenthal et al (1997) did find that a stress management intervention reduced clinical cardiac events.…”

Section: Recent Studiesmentioning

confidence: 99%

“…Overall treatment effects on cardiac outcomes were significantly greater in studies where positive results were found for proximal intervention targets-especially proximal psychological outcomes. Also of interest, the large recent studies that failed to replicate beneficial effects of psychosocial interventions (i.e., Frasure-Smith et al, 1997;Jones & West, 1996)-included in the analyses of Dusseldorp and colleagues (1999)-did not find significant treatment effects on emotional distress. In contrast, the positive findings for cardiac events and ambulatory ischemia reported by Blumenthal et al (1997)-not included in this meta-analysis-were accompanied by significant reductions in reported stress and hostility.…”

Section: Findings From Quantitative Reviewsmentioning

confidence: 99%

“…In studies with null results for cardiac outcomes (Frasure-Smith et al, 1997;Jones & West, 1996), it is not clear whether the failure to find significant reductions in psychosocial risk factors reflects ineffective interventions provided to appropriate patients or use of otherwise-effective treatments with patients who did not need them (Linden, 2000). For example, in Jones and West's (1996) study, stress management was provided to an unselected sample of consecutive patients, who reported generally low levels of psychological distress.…”

Section: Conclusion Regarding Intervention Researchmentioning

confidence: 99%

“…For example, in Jones and West's (1996) study, stress management was provided to an unselected sample of consecutive patients, who reported generally low levels of psychological distress. Future research should examine the efficacy of these interventions in patients selected for higher levels of psychosocial risk and, perhaps, examine interventions targeted to patients' predominant problem (i.e., general stress, anger, depression).…”

Section: Conclusion Regarding Intervention Researchmentioning

confidence: 99%

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Psychosocial influences on the development and course of coronary heart disease: Current status and implications for research and practice.

Smith¹,

Ruiz²

2002

Journal of Consulting and Clinical Psychology

292

208

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Psychosocial characteristics predict the development and course of coronary heart disease (CHD). In this review, the authors discussed human and animal research on psychophysiological mechanisms influencing coronary artery disease and its progression to CHD. They then reviewed literature on personality and characteristics of the social environment as risk factors for CHD. Hostility confers increased risk, and a group of risk factors involving depression and anxiety may be especially important following myocardial infarction. Social isolation, interpersonal conflict, and job stress confer increased risk. Psychosocial interventions may have beneficial effects on CHD morbidity and mortality, although inconsistent results and a variety of methodological limitations preclude firm conclusions. Finally, they discussed implications for clinical care and the agenda for future research.Coronary heart disease (CHD) is the leading cause of death in the United States; each year about 450,000 people die from CHD, and 1,000,000 experience an initial or recurrent coronary event (American Heart Association, 2001). Among healthy 40-year olds, between 40% and 50% of men and between 25% and 35% of women will later develop CHD (Lloyd-Jones, Larson, Beiser, & Levy, 1999). Over $100 billion is spent on CHD each year in the United States in direct medical costs, disability payments, and lost productivity (American Heart Association, 2001). This disease involves the three major topics composing behavioral medicine and health psychology, making it a central focus throughout their 30-year history. In the first (i.e., health behavior and prevention), modifiable behavioral risk factors (e.g., smoking, activity level, diet) are important risk factors for the development of CHD (Stamler et al., 1999;Wannamethee, Shaper, Walker, & Ebrahim, 1998), and behavior change is an essential component of prevention. In the second topic (i.e., stress and disease or psychosomatics), other psychological and social factors have more direct effects on the development and course of CHD through the intervening psychobiological effects of stress and negative emotions. In the third (i.e., psychosocial aspects of medical illness and care), established CHD has extensive emotional and social impacts on patients and their families, behavior is a key element of standard care (e.g., medication adherence, dietary change, exercise), and psychosocial interventions are useful additions to traditional medical and surgical treatment.Like the article on CHD in the previous special issue on behavioral medicine in this journal (Thoresen & Powell, 1992), we focused primarily on the second major topic-psychosocial influences on the development and course of CHD. We also reviewed one aspect of the third topic-interventions targeting psychosocial risk factors and their underlying psychophysiological mechanisms. Perhaps the most important implication of research on psychosocial risk factors for coronary disease is that interventions targeting these factors could reduce cardiac morb...

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The Influence of Anxiety and Depression on Outcomes of Patients With Coronary Artery Disease

Januzzi¹,

Stern²,

Pasternak³

et al. 2000

Arch Intern Med

268

146

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Psychological rehabilitation after myocardial infarction: multicentre randomised controlled trial

Cited by 246 publications

References 21 publications

Routine screening for psychosocial distress following hematopoietic stem cell transplantation

Routine screening for psychosocial distress following hematopoietic stem cell transplantation

Psychosocial influences on the development and course of coronary heart disease: Current status and implications for research and practice.

The Influence of Anxiety and Depression on Outcomes of Patients With Coronary Artery Disease

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