Psychological insulin resistance in geriatric patients with diabetes mellitus

Bahrmann, Anke; Abel, Amelie; Zeyfang, Andrej; Petrak, Frank; Kubiak, Thomas; Hummel, Jana; Oster, P.; Bahrmann, Philipp

doi:10.1016/j.pec.2013.11.010

Cited by 49 publications

(52 citation statements)

References 17 publications

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“…Previous studies have shown correlations between ghrelin to both BMI and insulin, However, they did not recommend its routine use of such parameters [11,12]. We have observed higher IR and insulin in T2DM with obesity similar to previously documented [13,14].…”

Section: Discussionsupporting

confidence: 80%

“…IR is a key factor in metabolic disorders such as hyperglycemia and hyperinsulinemia, which are promoted by obesity and may later lead to T2DM. Systematic assessment of barriers of insulin therapy, individualized diabetes treatment plans and information of patients may help to overcome such negative attitudes, leading to quicker initiation of therapy, improved adherence to treatment, and a better quality of life [13,14].…”

Section: Homa-β and Dmmentioning

confidence: 99%

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ASSOCIATION BETWEEN INSULIN,GHRELIN, HOMA-IR, HOMA-β, WHR AND BMI TO PLASMA GLUCOSE AND HbA1C AND ITS CLINICAL USEFULNESS IN T2DM PATIENTS WITH OBESITY

Selvanayagam

Gandhi²,

Arivazhagan³

et al. 2017

Asian J Pharm Clin Res

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Objectives: To evaluate new diabetic control monitoring parameters insulin, ghrelin, body mass index, waist-to-hip ratio, homeostasis model assessment-insulin resistance (HOMA-IR), and HOMA-β for Type 2 diabetes mellitus (T2DM) with obesity and to compare them with the existing diabetic control markers plasma glucose and glycosylated hemoglobin (HbA1c) and to recommended these additional tests to assess complications associated with kidney, liver, cardiac, and pancreas. Methods:A total of 100 T2DM patients with obesity who attended the sugar clinic attached to Apollo Speciality Hospitals, Vanagaram and who were on standard treatment and 50 age and sex matched controls attending the routine master health check in the same hospital were enrolled for the study. Fully automated analyzers and reagents and controls were used for all assays to ensure validity of the results obtained. For insulin and ghrelin assays, established commercial kits were used and all other parameters were calculated using formulae established previously. Graphpad online calculator was used to calculate t and p values. Results:The results obtained for both controls and patients for the set of additional parameters were compared with fasting plasma glucose (FPG), post prandial plasma glucose (PPPG), and HbA1c between controls, patients and controls with patients by calculating r and p values. Highly significant correlations were obtained in all comparisons. Conclusions:Very good associations (p<0.0001) were found between FPG, PPPG, and HbA1c to each of the new parameters for controls, patients and between controls and patients. These additional parameters may be done at fixed intervals of time to evaluate kidney, liver, cardiac and pancreatic complications/dysfunction in T2DM patients with obesity.

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Section: Discussionsupporting

confidence: 80%

Section: Homa-β and Dmmentioning

confidence: 99%

ASSOCIATION BETWEEN INSULIN,GHRELIN, HOMA-IR, HOMA-β, WHR AND BMI TO PLASMA GLUCOSE AND HbA1C AND ITS CLINICAL USEFULNESS IN T2DM PATIENTS WITH OBESITY

Selvanayagam

Gandhi²,

Arivazhagan³

et al. 2017

Asian J Pharm Clin Res

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“…Biomedical factors such as visual, auditory or upper limb impairment, which may limit ability to self injection, must be considered (1). Psychological barriers to insulin must be explored and addressed and sociocultural issues respected (2,3 advice from friends and relatives, is common in South Asia. Such self-erected barriers to insulin therapy must be bridged before insulin technique can be taught successfully (2,3).…”

Section: Introductionmentioning

confidence: 99%

“…Psychological barriers to insulin must be explored and addressed and sociocultural issues respected (2,3 advice from friends and relatives, is common in South Asia. Such self-erected barriers to insulin therapy must be bridged before insulin technique can be taught successfully (2,3). This is best done through a process of shared decision making, which promotes patient empowerment.…”

Section: Introductionmentioning

confidence: 99%

Insulin technique

Kalra¹,

Gupta²

2015

Sri Lanka J. Diabetes Endocrinol. Metab.

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“…Ancak, karmaşık bakım ve tedavi gerektiren diyabette bireylerin yukarıda sıralanan yaşam tarzı değişikliklerini yapmada zorlandıkları, uyum güçlüğü yaşadıkları, özellikle insülin tedavisine başlamada, sürdürmede ve önerilen şekilde kan şekeri takibini yapmada korku ve endişenin önemli yer tuttuğu görülmektedir. [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28] …”

Section: Introductionunclassified

Insulin injection and finger sticking fear in diabetic people

Çelik¹,

Pınar²

2014

Psi Hem Derg

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ÖZKarmaşık bakım ve tedavi gerektiren diyabette bireylerin kendi sağlık sorumluluğunu üstlenmeleri, gıda alımlarını ve egzersiz ayarlarını yapmaları, insülin enjeksiyonunu uygulamaları, önerilen şekilde kan şekerlerini ölçmeleri beklenmektedir. Ancak bireylerin yaşam tarzı değişikliklerini yapmada zorlandıkları ve uyum güçlüğü yaşadıkları bilinmektedir. Yapı-lan çalışmalarda insülin enjeksiyon ve parmak delme korkusunun tedaviye başlama, tedaviyi sürdürme, kan şekeri takibi yapma konularında engel oluşturduğu, kötü metabolik kontrol ve diyabet komplikasyonları ile ilişkili olduğu gösterilmiştir. Hem evrensel bir tanımının olmaması, hem de sağlık profesyonelleri tarafından gözardı edilmesi, yaygın görülen bu sorunun görünür kılınmasında ve yönetiminde güçlük yaratmaktadır. Diyabetin sonuçlarını önemli ölçüde etkileyen insülin enjeksiyonu ve parmak delme korkusunun belirlenmesi ve yönetiminde diyabet hemşi-relerine önemli sorumluluklar düşmektedir. Diyabet hemşiresi öncelikle bireyin yaşadığı korkunun nedenini tanımlamalı, derecesini tespit etmeli, korkunun yönetiminde hastalara eğitim vermeli, bu konuda diğer sağlık profesyonelleri ile işbirliği içinde çalışmalıdır. Bu derleme diyabetli bireylerde insülin enjeksiyon ve parmak delme korkusu, sonuçları ve yönetme stratejilerini gözden geçirmek amacıyla hazırlanmıştır.

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Psychological insulin resistance in geriatric patients with diabetes mellitus

Cited by 49 publications

References 17 publications

ASSOCIATION BETWEEN INSULIN,GHRELIN, HOMA-IR, HOMA-β, WHR AND BMI TO PLASMA GLUCOSE AND HbA1C AND ITS CLINICAL USEFULNESS IN T2DM PATIENTS WITH OBESITY

ASSOCIATION BETWEEN INSULIN,GHRELIN, HOMA-IR, HOMA-β, WHR AND BMI TO PLASMA GLUCOSE AND HbA1C AND ITS CLINICAL USEFULNESS IN T2DM PATIENTS WITH OBESITY

Insulin technique

Insulin injection and finger sticking fear in diabetic people

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