Psychological Characteristics and Quality of Life of Cancer Patients With Concomitant Cardiovascular Pathology

Порошина, Е Г; Вологдина, И В; Pestereva, E V

doi:10.17816/mechnikov20179183-88

Cited by 4 publications

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“…Існує низка досліджень, пов'язаних з психологічними характеристиками та якістю життя осіб з серцево-судинною патологією [2][3][4][5][6][7]. Основні механізми, що пояснюють, наприклад, зв'язок між депресією та серцевою недостатністю, можуть варіюватися від поведінкових до біологічних факторів ризику, включаючи гіперактивність симпатичної нервової системи.…”

Section: вступ постановка проблемиunclassified

Стрес Та Напруженість Як Патологічні Форми Несприятливого Впливу На Поведінку Літніх Жінок

Литвинчук¹

2021

ВНУОУ

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Стаття присвячена дослідженню стресу та напруженості як патологічних форм несприятливого впливу на поведінку літніх жінок. Було проведене медико-психологічне обстеження 35 респондентів похилого віку за допомогою опитувальника нервово-психічної напруги. З'ясовано, що стрес та напруженість, прояви психічної напруги літніх жінок з соматичною хворобою відрізняється від групи відносно здорових респондентів та більш сильно виражені у порівнянні з контрольною групою. Ключові слова: стресс; напруга; напруженість; соматична хвороба; літній вік; методи лікування; адаптаційна здатність організму.

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Section: вступ постановка проблемиunclassified

Стрес Та Напруженість Як Патологічні Форми Несприятливого Впливу На Поведінку Літніх Жінок

Литвинчук¹

2021

ВНУОУ

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“…Нами не было выявлено признаков депрессии у обследованных пациенток, что, вероятно, можно объяснить способностью реалистично воспринимать онкологическое заболевание, себя в роли пациента и стремлением к адаптации к своему заболеванию («я справлюсь», «выкарабкаюсь», «я поверил в медицину») [22]. При этом отношение к болезни без признаков нарушения психосоциальной адаптации не исключало у больных наличия повышенной тревоги.…”

Section: оригинальные статьи §unclassified

Age characteristics of risk cardiovascular complications in women with left breast cancer with preserved ejection fraction at the stage of chemotherapy and radiotherapy

Вологдина

Жабина

2019

Kardiologiia

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Aim. A study of the risk factors for middle-aged and elderly women HER2neu with negative left breast cancer and a normal ejection fraction at the stage of chemoradiotherapy in everyday clinical practice. Matherial and methods. 61 women with left breast cancer without severe cardiovascular pathology were examined at the stage of doxorubicin therapy and 3D conformal radiation therapy. Group 1 comprised 32 patients of middle age (49.8 ± 4.5 years). Group 2 comprised 29 elderly patients (68.3 ± 3.6 years). In addition to Score risk assessment, additional factors, including psychosocial factors, were studied. All patients underwent ECG, echocardiography and 24-hour ECG monitoring. Anxiety levels were assessed using the HADS scale and scale CH. D. Spielberger –Yu.L. Khanin. The study was conducted before the start of treatment, after the completion of the doxorubicin course and after the completion of the course of radiotherapy. Results with discussion. In middle-aged patients, moderate Score risk was found in 21.9%, in the elderly at 58.6% (p = 0.0043, RR 2.68, 95% CI 1.301–5.520). A high Score risk was found in 15.6% of middle-aged patients and 41.4% of elderly patients (p = 0.0438, RR 2.648, 95% CI 1061–6.607). The most common risk factors in the patients studied in addition to age were heredity, overweight, hypercholesterolemia and diabetes mellitus. All examined patients had moderate reactive anxiety. Patients of middle age have moderate personal anxiety, in elderly patients high personal anxiety. After treatment with doxorubicin in a cumulative dose not exceeding 360 mg/m2 , a reduction in the ejection fraction below 50% was found in 6 middle-aged patients and 17.2% in elderly patients. Asymptomatic diastolic dysfunction was detected in 31.3% of middle-aged patients and 55.2% of the elderly. In patients of both groups, after arranging treatment, arrhythmia was detected. Conclusions. The obtained data indicate to the need for in-depth examination of middle-aged and especially elderly patients with left breast cancer with an assessment of risk factors and conducting an in-depth examination using Echocardiography, 24-hour ECG monitoring and psychological testing to prevent and early detection of cardiovascular complications.

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Effect of arterial hypertension on quality of life and anxiety in middle-aged patients with breast cancer

Порошина

Вологдина

Жабина

et al. 2021

HERALD of North-Western State Medical University named after I.

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BACKGROUND: Arterial hypertension is one of the key risk factors for the development of cardiotoxicity in cancer patients. The importance for patients with left breast cancer is due to the possibility of the heart getting into the radiation area during treatment. The use of a method for assessing the quality of life and symptoms of anxiety can help improve treatment in such patients by increasing the interaction between a physician and a patient. AIM: The aim of the study is to assess the quality of life and the level of anxiety in patients with breast cancer, depending on the presence of arterial hypertension. MATERIALS AND METHODS: 67 patients with HER2neu negative cancer of the left breast have been examined. The average age is 42 (47; 63). All the patients after radical mastectomy and a course of chemotherapy with the inclusion of doxorubicin in a cumulative dose of no more than 360 mg/m2 have been hospitalized for 3D conformal radiation therapy. The first group included 32 patients with grade III comorbid hypertension; the second group included 35 patients without hypertension. The examination included an assessment of the status of an oncological patient according to the ECOG scale, echocardiography with an assessment of diastolic function, determination of the level of reactive and personal anxiety according to the Spielberger Khanin scale and quality of life using the SF-36 questionnaire. RESULTS: In the group of the patients with combined hypertension, left ventricular hypertrophy has been detected in 48 % of cases. In the patients of both groups with preserved ejection fraction, type I diastolic dysfunction has been detected (E/A 1): in the patients of the first group in 59.4 % of cases, in the patients of the second 31.4 % of cases. The difference obtained is due to the effect of hypertension on the left ventricular relaxation disorder. The level of reactive anxiety was significantly higher in the patients of the first group and amounted to 43.8 (41.2; 46.2) versus 38.4 (32.7; 42.6) points in the second group. The level of personal anxiety was high in the patients of both groups, which can be explained by the predominant influence of cancer. In the patients of both groups, there was a decrease in indicators according to the SF-36 questionnaire on all scales. The most significant changes have been obtained on the scales of physical functioning, role-based physical functioning, pain, vitality and general health. Cancer patients with concomitant hypertension rated their health status lower, while they are more likely to note a decrease in daily role activity as a result of their emotional state. CONCLUSIONS: The data obtained indicate that arterial hypertension has a significant negative effect on the level of reactive anxiety and quality of life indicators of breast cancer patients, which is of great importance in the formation of a patient-oriented approach to the therapeutic support of specific treatment in such patients.

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Psychological Characteristics and Quality of Life of Cancer Patients With Concomitant Cardiovascular Pathology

Cited by 4 publications

References 0 publications

Стрес Та Напруженість Як Патологічні Форми Несприятливого Впливу На Поведінку Літніх Жінок

Стрес Та Напруженість Як Патологічні Форми Несприятливого Впливу На Поведінку Літніх Жінок

Age characteristics of risk cardiovascular complications in women with left breast cancer with preserved ejection fraction at the stage of chemotherapy and radiotherapy

Effect of arterial hypertension on quality of life and anxiety in middle-aged patients with breast cancer

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