Psychological Aspects and Depression in Patients with Retinitis Pigmentosa

Moschos, Marilita M; Chatzirallis, Alexandros; Chatziralli, Irini

doi:10.5301/ejo.5000590

Cited by 23 publications

(24 citation statements)

References 26 publications

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“…It is important to note that the depressive state was found to be significantly associated with every aspect of visual function including the BCVA in the better or worse eye, and the FAS, FFS, FVS and the NEI-VFQ25 subscale score. These significant correlations were also found in other studies [ 12 – 15 ]. Thus, Hahm et al found a significant relationship between visual functions and a depressive state in RP patients, however it was not found in such visual functional tests as the weighted visual acuity score or FVS [ 12 ].…”

Section: Discussionsupporting

confidence: 89%

Quantitative analyses of factors related to anxiety and depression in patients with retinitis pigmentosa

et al. 2018

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The purpose of this study is to determine the factors related to anxiety and depression in patients with retinitis pigmentosa (RP). The status of anxiety and depression was determined in RP patients with the Hospital Anxiety and Depression Scale (HADS) questionnaire which consisted of subscales for HADS-anxiety (HADS-A) and HADS-depression (HADS-D). The vision-specific quality of life (VSQOL) was assessed with the National Eye Institute Visual Function Questionnaire 25 (NEI-VFQ25). The correlations between the HADS-A or HADS-D scores and vision-related clinical parameters such as the best-corrected visual acuity (BCVA), Functional Acuity Score, Functional Field Score, Functional Vision Score, the NEI- VFQ25 subscale score were determined. The socioeconomic status, such as the work status and membership in the RP society, was investigated to determine the factors related to the HADS-A and HADS-D scores. One hundred and twelve RP patients (46 men and 66 women) with mean age of 60.7±15.4 (standard deviation) years were studied. The HADS-A score was not significantly correlated with any visual functions but was significantly correlated with the general health condition (r = -0.34, P<0.001) and the role limitation (r = -0.20, P = 0.03) of the NEI-VFQ25 subscale. The HADS-D score was significantly correlated with all the visual functions (r = -0.38 to 0.29, P<0.001), the NEI-VFQ25 subscale score (r = - 0.58 to -0.33, P<0.001) by Spearman’s correlations. The HADS-A score was significantly higher in the members of the RP society than in non-members (P = 0.013). The mean HADS-D score of employed individuals was significantly lower than that of unemployed ones (P = 0.001) by the Mann-Whitney U test. The results indicate that visual function impairments and vision-related quality of life are associated with a depressive state, and the general health condition is related to anxiety in RP patients. Being employed may be strongly correlated with the degree of depression in RP patients.

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Section: Discussionsupporting

confidence: 89%

Quantitative analyses of factors related to anxiety and depression in patients with retinitis pigmentosa

et al. 2018

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“…This study did not record whether participants were seeking treatment from a health professional or taking any medication at the time of the study. This may have altered the results if it had been taken into account as previous research has stated that treatments and therapies impact VRQoL [ 2 , 7 , 9 ]. Thus, future research aimed at a general community population should initially record treatment status and, if it is a longitudinal design, monitor any changes in treatment status.…”

Section: Discussionmentioning

confidence: 99%

“…This suggests a relationship between emotional health and coping strategies, where engaging or disengaging coping strategies may indicate emotional health levels. Being diagnosed with RP is associated with developing depressive symptoms, poor mental wellbeing, and lower levels of general happiness with life [ 7 ]. Therefore, coping strategies and emotional health seems to be highly associated with each other.…”

Section: Introductionmentioning

confidence: 99%

Coping strategies, vision-related quality of life, and emotional health in managing retinitis pigmentosa: a survey study

Anil

Garip

2018

BMC Ophthalmol

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BackgroundRetinitis pigmentosa is a group of genetic progressive retinal dystrophies that may adversely affect daily life. Those with RP should develop adaptive coping strategies to manage their condition. This study investigates the relationship between engaging (ECS) and disengaging coping strategies (DCS), vision-related quality of life (VRQoL), and emotional health, in adults living at home with retinitis pigmentosa.MethodOne hundred and five participants (70 female; meanage of 46.98, SDage = 13.77) completed a cross-sectional survey. The questionnaire booklet consisted of the Coping Strategies Inventory – Short Form (32 items), the National Eye Institute Visual Functioning Questionnaire 25 (25 items), Marylands Trait Depression Scale (18 items), the Warwick-Edinburgh Mental Well-being Scale (14 items), and the Subjective Happiness Scale (4 items).ResultsData was analysed with a two-block hierarchical multiple regression, with the first block controlling for the demographic data (age, sex, years since retinitis pigmentosa diagnosis, number of comorbidities, participant-perceived retinitis pigmentosa severity, and knowing RP type) and the second block consisting of primary measures (type of coping strategy, VRQoL, and Emotional Health). Type of coping strategy was found to impact psychosocial variables of VRQoL, not overall VRQoL. These psychosocial VRQoL variables had a positive association with ECS and a negative association with DCS. Emotional Health increased with ECS and decreased with DCS. There was a larger impact of DCS on VRQoL and Emotional Health compared to ECS, that is, VRQoL and Emotional Health decreased more with increasing DCS than VRQoL, and Emotional Health increased with increasing ECS.ConclusionIn concordance with previous research, ECS increased with increasing VRQoL and DCS decreased with increasing VRQoL. However, the findings also indicated that DCS had a greater impact than ECS on VRQoL and Emotional Health. This suggests that diminishing DCS should be prioritised over developing ECS to positively influence VRQoL and Emotional Health. Further research should investigate the impact of reducing DCS compared to increasing ECS, and how this may influence VRQoL and Emotional Health.Electronic supplementary materialThe online version of this article (10.1186/s12886-018-0689-2) contains supplementary material, which is available to authorized users.

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“…Several studies have evaluated the aforementioned association, detecting depression in patients with age-related macular degeneration [ 25 ], glaucoma [ 28 ], retinitis pigmentosa [ 29 ], and Stargardt disease [ 30 ]. As for the KC, studies demonstrated controversial conclusions.…”

Section: Introductionmentioning

confidence: 99%

Psychological Aspects and Depression in Patients with Symptomatic Keratoconus

Moschos

Gouliopoulos

Kalogeropoulos

et al. 2018

Journal of Ophthalmology

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Purpose To assess the psychological status of keratoconus sufferers and to determine the relationship between depression and visual impairment in this group of patients. Methods Fifty-six patients with keratoconus and forty-seven age- and gender-matched healthy control subjects were retroprospectively analyzed. Every participant underwent a complete ophthalmological examination. Keratoconus diagnosis was confirmed with corneal topography and tomography. Zung Depression Inventory Questionnaire and Patient Health Questionnaire-9 (PHQ-9) were completed by everyone. Results Visual acuity (logMAR 0.53 ±0.30 versus 0.11 ± 0.16), PHQ-9 score (10.20 ± 4.00 versus 5.40 ± 5.01), and Zung score (46.52 ± 8.70 versus 38.53 ± 8.41) showed a statistically significant difference between keratoconus patients and healthy controls (p < 0.001 for all). Worse visual acuity was strongly correlated with older individuals (rho = 0.339, p=0.011) and higher PHQ-9 (rho = 0.765, p < 0.001) and Zung score (rho = 0.672, p < 0.001). Conclusion Depressive disorders appear to be directly associated with keratoconus, both in frequency and intensity. Worse visual acuity and older age could be identified as predictive factors for their emotional status. Moreover, the disease itself could be recognized as an independent risk factor for depression development, underlying the need for close monitoring and supportive management. To the best of our knowledge, our study is the first in the literature to elaborate the association between keratoconus and depression, by assessing two different questionnaires simultaneously.

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Psychological Aspects and Depression in Patients with Retinitis Pigmentosa

Cited by 23 publications

References 26 publications

Quantitative analyses of factors related to anxiety and depression in patients with retinitis pigmentosa

Quantitative analyses of factors related to anxiety and depression in patients with retinitis pigmentosa

Coping strategies, vision-related quality of life, and emotional health in managing retinitis pigmentosa: a survey study

Psychological Aspects and Depression in Patients with Symptomatic Keratoconus

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