Psychogenic and Neurogenic Abnormalities after Perinatal Insecticide Exposure

Mactutus, Charles F.; Tilson, Hugh A.

doi:10.1007/978-1-4613-2189-7_15

Cited by 5 publications

(3 citation statements)

References 81 publications

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“…It has been associated with congenital heart defects 9 , structural defects of the gastrointestinal tract, genitourinary system 10 , musculoskeletal system, and neurodevelopmental disorders 11 . In North Carolina, exposure to residential pesticides was associated with hypospadias in the case of mepiquat chloride, paraquat, and pendimethalin; while cardiac atrial septal defects were associated with glyphosate, cyhalothrin, s-metolachlor, mepiquat, and pendimethalin 12 .…”

Section: Prenatal Exposurementioning

confidence: 99%

Pesticide exposure and its effects on intrauterine and postnatal development

Calderón-Garcidueñas¹,

Martínez-Valenzuela²,

Waliszewski-Kubiak³

2023

PER

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Background:The period between conception and the first two postnatal years is critical and marks the individual, largely determining their health and disease patterns. Objective: To review the effect of pesticide exposure in utero and in the 1 st years of life. Materials and methods: The scientific literature in relation to the subject was reviewed, both in animal models and in humans. Results: The presence of various types of pesticides in umbilical cord blood and in meconium is well documented in newborns worldwide, including Mexico. Pesticides have been associated with low birth weight, and various birth defects at the heart, gastrointestinal tract, genitourinary system, musculoskeletal system, and neurodevelopmental disorders. These substances may play a role in the increase in cases of autistic disorder. Conclusions: Despite the evidence, there are no public policies in many countries, including Mexico, to control the sale and use of pesticides. It is required to prevent exposure to these substances in the population and to do follow-up studies in mother-child pairs where exposure is suspected.

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Section: Prenatal Exposurementioning

confidence: 99%

Pesticide exposure and its effects on intrauterine and postnatal development

Calderón-Garcidueñas¹,

Martínez-Valenzuela²,

Waliszewski-Kubiak³

2023

PER

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“…But most of these chemicals reported to be carcinogenic [1], [2] mutagenic [2], [3] teratogenic [3], [4] immunosuppressive [5], [6] create endocrine dysfunction such as hypothyroidism or high estrogenic activity [7], [8] disturb reproductive processes [9], [10] growth depressants [11], [12] induces several psychogenic and neurogenic abnormalities in adult stages [13], [14], and are associated with abortions, premature deliveries, still births and infants with low birth weights [15]- [18]. OCPs have been in use in India nearly for a half century now.…”

Section: Introductionmentioning

confidence: 99%

Pesticide Burden in Women from Jaipur in Relation to Ethnicity, Religion and Addiction Habit

Sharma¹,

Bhatnagar²

2017

IJESD

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Abstract-Pesticides, human health and safety of environment is of global concern. Organochlorine pesticides (OCPs) have been used for several decades in development of agriculture and protection of public health. Their low degradation nature, accumulation in living beings, biomagnification and biological effects in natural exposure and animal experimentation led to the legislation of allowable concentrations. This legislation was intended to prevent the exposure of the general population to harmful levels of these xenobiotics. A monitoring study was therefore, conducted in Jaipur (India) in which the circulating blood of pregnant woman subjects was analyzed for pesticide residues viz-aldrin, isomers of HCH, metabolites of heptachlor and DDT by using gas liquid chromatography. Study revealed the effect of religion (dietary habits), ethnicity and addiction habits on the accumulatory pattern of pesticide residues in the blood of pregnant women.Index Terms-Gas chromatograph, human blood, Jaipur city, organochlorine pesticide residue.

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“…Prenatal exposure to pesticides has been associated with adverse pregnancy outcomes, such as birth defects and severe neurological disorders [1,2]. However, the effects of prenatal exposure to pesticides at ambient pollution concentrations are as yet unknown.…”

Section: Introductionmentioning

confidence: 99%

Detection of Several Classes of Pesticides and Metabolites in Meconium by Gas Chromatography-Mass Spectrometry

Bielawski

Ostrea

Posecion

et al. 2005

Chroma

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A solid phase extraction method was developed to isolate multiple classes of parent pesticides from meconium. A methanolic/hydrochloric acid methyl ester derivatization with liquid-liquid extraction technique was also developed for the analysis of metabolites. Identification and quantitation was by electron impact gas chromatography-mass spectrometry. For the parent compounds and metabolites, recoveries in spiked meconium ranged between 72-109%, with coefficients of variation ranging from 1.55-16.92% and limits of detection between 0.01-4.15 μg g −1 . Meconium samples obtained from infants in the Philippines were assayed using these methods, and propoxur, cypermethrin, pretilachlor, malathion, 4,4′-dichlorodiphenyltrichloroethylene, bioallethrin, and cyfluthrin were detected.

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Psychogenic and Neurogenic Abnormalities after Perinatal Insecticide Exposure

Cited by 5 publications

References 81 publications

Pesticide exposure and its effects on intrauterine and postnatal development

Pesticide exposure and its effects on intrauterine and postnatal development

Pesticide Burden in Women from Jaipur in Relation to Ethnicity, Religion and Addiction Habit

Detection of Several Classes of Pesticides and Metabolites in Meconium by Gas Chromatography-Mass Spectrometry

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