Psychiatric Disorders and Cardiovascular System: Heart-Brain Interaction

Nasser, Fernando José; Almeida, Marcos de; Silva, Lucas Saraiva da; Almeida, Renata Gudergues Pereira de; Barbirato, Gustavo Borges; Mendlowicz, Mauro V.; Mesquita, Cláudio Tinoco

doi:10.5935/2359-4802.20160003

Cited by 14 publications

(15 citation statements)

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“…It has been proposed that in addition to behavioral factors, the sympathetic hyperactivity in response to distress can lead to left ventricular dysfunction, decreased baroreflex dysfunction and decreased heart rate variability. 28,29 …”

Section: Discussionmentioning

confidence: 99%

Neurocognitive impairment after acute coronary syndrome: Prevalence and characterization in a hospital-based cardiac rehabilitation program sample

Silva

Pereira

Rocha

et al. 2018

J Cardiovasc Thorac Res

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Introduction: Prospective studies have shown the relation between acute coronary syndrome (ACS) and neurocognitive dysfunction with prevalence ranging between 10.51% and 66.8%. The present study aims to determine the prevalence level of neurocognitive dysfunction; the relations between sociodemographic, clinical and emotional variables and neurocognitive functioning in a sample of ACS patients. Methods: The sample comprised of 53 patients engaged in cardiac rehabilitation within 3 months after an ACS. Patients with any medical history of neuropsychiatric problems prior to the ACS and illiterate subjects were not included in the study. Results: The majority of the sample (85%) exhibits some degree of cognitive impairment, with 84.8% showing verbal fluency impairment, 60.3% memory impairment and only 26,4% had language compromised. Neurocognitive general functioning was correlated with age. Memory domain was negatively correlated with the number of daily smoked cigarettes before the ACS. Verbal fluency was influenced by schooling. Language domain was correlated with mean diastolic pressure and with the type of profession, visuospatial domain was correlated with schooling, number of cardiovascular risk factors, distress, anxiety levels and type of ACS. Conclusion: Prevalence rate of neurocognitive dysfunction is considerably high. Besides global neurocognitive functioning, verbal fluency and memory are the most affected domains. Several variables were related to neurocognitive performance: sociodemographic; cardiovascular risk factors; clinical; psychological. The underlying mechanisms of neurocognitive dysfunction should be further explored.

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Section: Discussionmentioning

confidence: 99%

Neurocognitive impairment after acute coronary syndrome: Prevalence and characterization in a hospital-based cardiac rehabilitation program sample

Silva

Pereira

Rocha

et al. 2018

J Cardiovasc Thorac Res

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“…They have been also been considered independent risk factors for CAD and CVD, in addition to altering their natural history. 89,90…”

Section: General Aspects Of Old Age Risk Factors and Preventionmentioning

confidence: 99%

“…First generation antidepressants include MAOI and tricyclic and tetracyclic antidepressants (TCA and TeCA, respectively); second-generation antidepressants include selective serotonin reuptake inhibitors (SSRI), selective norepinephrine reuptake inhibitors (SNRI), and atypical antidepressants. 89,96…”

Section: General Aspects Of Old Age Risk Factors and Preventionmentioning

confidence: 99%

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Updated Geriatric Cardiology Guidelines of the Brazilian Society of Cardiology - 2019

Feitosa-Filho

Peixoto²,

Pinheiro³

et al. 2019

Arquivos Brasileiros De Cardiologia

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“…Dantas [21] em seu estudo refere as dificuldades de determinar o verdadeiro papel que o estresse exerce na epidemiologia das DAC. Já segundo Nasser et al [22] pacientes deprimidos têm risco 1,6 vezes maior que pacientes não deprimidos de apresentar evento cardíaco nos primeiros 24 meses após o diagnóstico de DAC e são significativamente mais propensos a morrer no ano seguinte ao diagnóstico. Além disso, Rugulies [23] analisou 11 estudos de coorte que avaliaram a associação entre depressão e DAC, constatando que as pessoas com depressão tinham um risco 2,5 vezes maior de sofrer IAM ou morte de causa coronariana do que a população em geral.…”

Section: Resultsunclassified

Associação entre fatores de risco cardiovasculares e a presença de doença arterial coronariana

Maldonado¹,

Silva²,

Pereira³

et al. 2019

archmed

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Objetivo: associar os fatores de risco e a presença da doença arterial coronariana em pacientes submetidos à cintilografia de perfusão de miocárdio. A doença arterial coronariana é uma das principais causas de morte no Brasil e no mundo por isso, detectá-la anteriormente às manifestações clínicas ou complicações é crucial para evitar a progressão da doença. Materiais e Métodos: foi realizado um estudo observacional, transversal e retrospectivo a partir da análise aleatória de 226 prontuários de pacientes submetidos a cintilografia de perfusão do miocárdio entre agosto de 2010 e agosto de 2015. Avaliou-se a razão de chances (Odds Ratio) dos seguintes fatores de risco: tabagismo, diabetes mellitus tipo II, hipertensão arterial sistêmica, dislipidemia, obesidade, sobrepeso, sedentarismo, estresse e antecedentes familiares. Foram calculados riscos atribuíveis ao Intervalo de Confiança 95%. Resultados: dentre os fatores analisados, o diabetes aparece como o principal fator de risco não evitável para a doença com razão de chances ajustada de 3,45 (Intervalo de confiança 95%). A dislipidemia com Odds Ratio ajustada de 2,45 (Intervalo de confiança 95%) e hipertensão com Odds Ratio ajustada de 1,97 (Intervalo de confiança 95%). Conclusões: o presente estudo permitiu associar os fatores de risco e a presença da doença arterial coronariana em pacientes submetidos à cintilografia de perfusão de miocárdio, sendo o diabetes o principal fator de risco não evitável para a doença. Dentre os fatores de risco evitáveis (tabagismo, sedentarismo, estresse, sobrepeso/obesidade e sobrepeso) nenhum apresentou associação significativa com a doença.

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Psychiatric Disorders and Cardiovascular System: Heart-Brain Interaction

Cited by 14 publications

References 0 publications

Neurocognitive impairment after acute coronary syndrome: Prevalence and characterization in a hospital-based cardiac rehabilitation program sample

Neurocognitive impairment after acute coronary syndrome: Prevalence and characterization in a hospital-based cardiac rehabilitation program sample

Updated Geriatric Cardiology Guidelines of the Brazilian Society of Cardiology - 2019

Associação entre fatores de risco cardiovasculares e a presença de doença arterial coronariana

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