Psychiatric and behavioral side effects of the newer antiepileptic drugs in adults with epilepsy

A 17-Year-Old with Aggressive Behavior after Beginning Therapy for Epileptic Seizures

“…1 Psychosis including extreme aggression is rare, found in less than 0.7% of those prescribed LEV. 1,2 This case shows the challenges associated with identifying rare behavioral changes in patients receiving multiple psychoactive medications, and the diagnostic complexity in psychogenic pathology. It also reinforces clinical appreciation of the possibility of medication-induced psychosis and behavior changes related to agents regularly prescribed by physicians of diverse specialties.…”

Epileptic seizures in patients with glioma: A single centrebased study in China

“…Levetiracetam acceptability was noted to be excellent with satisfactory seizure control and adverse events of lesser frequency. Although, significantly more number of psychiatric or behavioral adverse events were reported to be caused by levetiracetam than by gabapentin or lamotrigine [17]. Fortunately, none of the patients experienced the above kinds of adverse effects and in any case, it is important to be aware of such effects while utilizing levetiracetam for seizure control.…”

Treatment of partial seizures with gabapentin: Double‐blind, placebo‐controlled, parallel‐group study*

“…Data from 1286 patients were also reviewed for the incidence of psychiatric side-effects. 18 These effects were reported most commonly in patients receiving levetiracetam (16%) and resulted in dosage or medication change in many (11.1%). In order of frequency, topiramate (7.9%), oxcarbazepine (5.7%), felbamate (4.6%), and lamotrigine (3.9%) were also associated with psychiatric effects; gabapentin had the lowest incidence (2%).…”