Psoriasis: the modern idea of dermatosis

Askhakov, Marat; Chebotarev, Vyacheslav

doi:10.14300/mnnc.2017.12065

Medical news of the North Caucasus

2017

DOI: 10.14300/mnnc.2017.12065

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Psoriasis: the modern idea of dermatosis

Marat Askhakov¹,

Vyacheslav Chebotarev²

Abstract: Ставропольский государственный медицинский университет, Россия psoriasis: the modern idea of dermatosis askhakov m. s., chebotaryov V. V. stavropol state medical university, russia Представлены современные данные о состоянии псориаза и методах его терапии. Ключевые слова: псориаз, терапия, диагностика, патогенез, биологические препараты This review presents current data on the status of psoriasis and methods of its treatment.

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Psoriasis and cardiovascular comorbidity – a mutually aggravating relationship

Kovaleva

Vedler

2023

Medicinskij sovet

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Introduction. The systemic psoriatic process affects not only the skin, but also other organ systems, including the cardiovascular system. Immunopathological inflammation that occurs in the skin and articular tissues is a central link in the pathology of the cardiovascular system in psoriasis.Objective. Identify diseases of the cardiovascular system and factors of their development in patients with psoriasis and to assess their severity depending on the severity of dermatosis.Materials and methods. The study included 406 patients with psoriasis aged 18 to 74 years, who were divided into three subgroups depending on the severity of the course. Assessment of the state of the cardiovascular system was carried out using the following methods: uestionnaire, clinical, physical, laboratory and statistical. The comparison group consisted of 200 people.Results. In 53.9% of patients, psoriasis occurred against the background of cardiovascular comorbidity. More than 90% of patients with moderate to severe psoriasis have more than three risk factors for CCC diseases. Patients are more susceptible to the development of hypertension, hypercholesterolemia, obesity, abdominal obesity, stress and smoking. The higher the cardiovascular risk, the more severe psoriasis is.Conclusions. The presence of unmodified and modifiable risk factors for the development of cardiovascular diseases is aggravating for the course of psoriasis, which means that the risk of undesirable fatal events is higher. Patients with psoriasis need additional preventive measures aimed at preventing the development of cardiovascular pathology.

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Psoriasis and cardiovascular comorbidity – a mutually aggravating relationship

Kovaleva

Vedler

2023

Medicinskij sovet

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Psoriasis: can a systemic disease become a way of life?

Armakov

2021

Spravočnik Vrača Obŝej Praktiki (Journal of Family Medicine)

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According to the literature, about 3% of the world's population suffers from psoriasis; the highest prevalence is observed in the countries of Western Europe and Scandinavia, while this disease is less common among representatives of the Mongoloid and Negroid races. In different countries, the proportion of psoriasis is from 10 to 40% in the total structure of skin diseases. This pathological process has a multifactorial nature; it is based on hyperproliferation of keratinocytes with impaired differentiation, which clinically manifests itself in the form of damage to the skin, nails and joints. Psoriasis is one of the most common dermatoses; men and women suffer from it equally often. The triggering factor for the development of psoriasis can be a psychoemotional stressful situation, as well as the impact of other environmental factors, including hypothermia, trauma, infections, and taking certain medications. As a result of exposure to provoking endogenous and exogenous factors, autoimmune mechanisms, which are based on increased activity of T cells, are triggered. About 70% of psoriasis patients have mild to moderate severity of the disease. Despite the wide range of drugs used to treat psoriasis, they do not demonstrate high efficiency, and the prevalence of this pathology is growing every year. The existing methods of treatment help to cope with exacerbations and relieve inflammation, however, it is impossible to completely cure this disease, and the risk of relapse always remains. One of the tasks of doctors involved in the treatment of psoriasis is not only to reduce the severity of symptoms, but also to teach a patient suffering from psoriasis to live a full life and not depend to a large extent on the manifestations of the disease and the opinions of others.

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Psoriasis: the modern idea of dermatosis

Cited by 2 publications

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Psoriasis and cardiovascular comorbidity – a mutually aggravating relationship

Psoriasis and cardiovascular comorbidity – a mutually aggravating relationship

Psoriasis: can a systemic disease become a way of life?

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