Pseudotumor of the Sigmoid Colon Causing Bowel Obstruction

Sehmbey, Gurbir; Al-Jashaami, Layth; Nanda, Rakesh

doi:10.14309/crj.0000000000000039

Cited by 1 publication

(4 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There is ongoing effort to define and sub-classify these tumours [7] , [11] . This is particularly true for those with more aggressive phenotypes, such as inflammatory fibrosarcoma and inflammatory leiomyosarcoma, which carry a risk of recurrence and the ability to metastasize and are associated with mortality, reflecting a more malignant process [5] , [10] . Similarly, the distinct morphological and molecular patterns of inflammatory myofibroblastic tumours have distinguished them as a separate body [7] .…”

Section: Discussionmentioning

confidence: 99%

“…The stomach and omentum are the predominant sites, followed by the small intestine, colon, and oesophagus [8] . Colonic IPTs, although rare, have been documented in association with Crohn's disease and chronic diverticulitis [3] , [5] , [12] . A review of colonic IPTs conducted in 2015 found only 18 prior literature records of IPTs in the colon [13] .…”

Section: Discussionmentioning

confidence: 99%

“…This variability is also true for computed tomography (CT), in which they may vary in terms of attenuation, homogeneity, filling, and definition, depending on the degree of necrosis, fibrosis and infiltration [2] , [3] , [4] , [6] , [8] , [9] . These features may mimic haematological or metastatic lesions, making them indistinguishable on radiological assessment alone [4] , [5] , [6] , [9] . For this reason, we doubt whether pre-operative imaging would have facilitated a more accurate diagnosis of our patient.…”

Section: Discussionmentioning

confidence: 99%

“…Inflammatory pseudo-tumours (IPTs) are rare mesenchymal masses that occur in <0.0001% of the population [2] , [3] , [4] . First described as IPTs in 1954 by Uniker and Iversion [4] , these tumours are benign lesions associated with non-specific inflammatory cellular infiltration with spindle-cell proliferation and are often reactive, infective, or immunological in nature [5] . They have been described predominantly in the lungs to date; however, they may occur in any anatomical location, mostly in children and young adults [2] , [3] , [4] .…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Inflammatory pseudo-tumour of the colon mimicking acute appendicitis: A case report

Zulu

Krüger

Morare

et al. 2022

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

Introduction Inflammatory pseudo-tumour (IPT) of the colon is a rare entity with an obscure pathophysiology and largely indeterminate aetiology. Presentation of case A young male patient presented with an Alvarado score of 9/10 and was admitted for appendectomy. An irregular hepatic flexure mass was discovered intraoperatively. The patient underwent an oncological right hemicolectomy with lymphadenectomy under the supposition that it was malignant and recovered with no short or long-term repercussions. Haemoxylin and eosin staining of the mass revealed features of a benign IPT. Discussion IPTs have clinical and radiological features that may be indistinguishable from those of malignancies, often resulting in extensive oncological resections despite recurrence and malignant transformation being negligibly rare. Conclusion Benign pathologies such as IPT that mimic malignancy can sometimes result in extensive investigations or radical resections, the justification of which can only be a point of contention in retrospect. The following report explores our experience with one such patient and is accompanied by a review of the literature.

show abstract