Pseudopregnancy in the bitch: the current view on aetiology and treatment

Allen, W. Edward

doi:10.1111/j.1748-5827.1986.tb03959.x

Cited by 20 publications

(31 citation statements)

References 22 publications

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“…Included can be nervousness, guarding an area, making a nest (66.1% of nonpregnant females), abdominal distention, mammary gland development with or without lactation (78.6%), external signs of labor, self-nursing, and guarding or carrying a stuffed toy or other object (53.6%). 3 an ovariohysterectomy within 3 months after estrus can also result in a sharp drop in progesterone and signs of pseudocyesis, including lactation, by 4 days postsurgery. Because the behaviors of pseudocyesis are typical of normal behaviors that start about the time progesterone levels decrease, it is reasonable to expect that up to 8 weeks may be needed for the changes of pseudocyesis to gradually stop.…”

Section: Female Sexual Behavior Problemsmentioning

confidence: 99%

Female Canine Sexual Behavior

Beaver

2009

Canine Behavior

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Section: Female Sexual Behavior Problemsmentioning

confidence: 99%

Female Canine Sexual Behavior

Beaver

2009

Canine Behavior

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“…The condition is usually mild and most cases recover spontaneously after a few weeks. Bitches with more severe signs can be treated with a variety of drugs, mainly reproductive steroids (Allen 1986). It has been suggested that all bitches develop pseudopregnancy but only some show signs of the condition.…”

mentioning

confidence: 99%

“…First, the owners find that an animal which was apparently clinically normal or only mildly affected before the operation has become a long-term problem. Secondly, conventional therapy for pseudopregnancy is much less efficient in such ovariectomised cases (Allen 1986) and, furthermore, the unknown processes which result in the normal spontaneous recovery in the entire animal appear not to be functional. This paper describes 32 bitches which had been ovariohysterectomised mainly for sterilisation, but, in a small number of cases, in an attempt to cure a pseudopregnancy.…”

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confidence: 99%

A study of the aetiology of pseudopregnancy in the bitch and the effect of cabergoline therapy

et al. 1999

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Thirty-two permanently pseudopregnant bitches were treated with the anti-prolactin drug cabergoline. They had all been ovariohysterectomised up to five months after their last season, in some cases over two years previously, when most were reported as showing no signs of the condition. The clinical signs were mainly behavioural, the majority being aggressive, and a small number were lactating. The efficiency of the cabergoline therapy was classified by the owners as 'excellent' or 'good' in 50 per cent of the cases, and fair in 36 per cent. The rate of success was markedly better than in similar cases treated with reproductive steroids. In all but one of the bitches, the plasma prolactin concentrations were basal.

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“…From this point of view, the inhibition of prolactin secretion has been the most efficient method of control. Most cases are treated on the request by the owner for several reasons (Allen 1986;Arbeiter et al 1988;Dumon et al 1993;Jochle et al 1989;Onclin et al 1995).…”

Section: Introductionmentioning

confidence: 99%

“…The receptors are located in luteotrophic cells, which synthesize and secrete prolactin in the anterior pituitary gland in humans and animals (Allen 1986;Arbeiter et al 1988;Braakman et al 1993;Dumon et al 1993;Johnston 1986;Jochle et al 1987). Dumon et al (1993), report that serotonin is an antagonist of metergoline, while cabergoline and bromergocryptine are the agonists of dopamine.…”

Section: Introductionmentioning

confidence: 99%

The Use of Cabergoline for Treatment of Pseudopregnancy in Dogs with the Purpose of Suppressing Lactation

Baştan¹,

Fmdik²,

Erunal³

et al. 1998

Reprod Domestic Animals

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This study was performed on a total of 22 dogs of various breeds and ages (from 10 months to 8 years of age, mean age 3.3 years) with the aim of treating animals diagnosed as having pseudopregnancy, and in cases with whom cessation of lactation was necessary because of the death of their young, their separation from the mother, milk eclampsia or mastitis. For treatment, cabergoline at a dose of 5pg;kg d orally was applied and this was continued over 4 days. During the pretreatment period, a check of the general health state and ultrasonographic examination were made. Changes occurring in the post-treatment period and side effects were recorded. In determining the efficacy of the treatment, the appearance of mammary glands, changes occurring in the nature of secretion and lessening in the amount of secretion as well as behavioural changes were regarded as criteria. Appearance of mammary glands and changes occurring in the nature of secretion have been expressed with various scaling systems and all findings related to each dog were recorded in the anamnesis form. The score for mammary gland appearance changed to '0' in all dogs (n = 22): in 40.9% (n = 9) on the third day. in 54.6% (n = 12) on the fourth day and in 4.5% (n = 1) on the sixth day, respcctively. The score for the nature of secretion changed to 'normal' in all dogs (n = 22); in 4.5'y0 (n = 1) on the second day, 50% (11 = I 1) on the third day, 41 .O% (11 = 9) on the fourth day and 4.5% (n = I ) on the fifth day, respectively. In dogs rcceiving cabergoline normal behaviour returned in all dogs (n = 22); in 22.7% (n = 5) on the first day, 31.8% (n = 7) on the second day and 45.5% (n = 10) on the third day, respectively. In all dogs receiving cabergoline, body temperature was measured for 4 days following treatment, yielding mean temperatures of 39.4 f 0.4-C on the first day, 39.2 k 0.3-C on the second day, 38.9 k 0.3'C on the third day and 38.8 0.3"C on the fourth day. respectively. As a result of this study, it has been concluded that for the prevention of the symptoms of pseudoprcgnancy and that of an undesirable lactation in dogs. cabergoline in cfficient in treating these conditions. N o side-effects were seen with the exception of one case where vomiting was observed. 39,4 0,4 C am 1 . Tag, 3Y,2 k 0 , 3 T am 2. Tag. 38;') 0,3-C: am 3. Tag und 38,8 k 0,3 C am 4. Tag. Als Ergebnis dieser Studie kann geschluIjfolgert werden, da8 Cabergolin zur Vorbeugung gegen Symptome einer Pseudograviditat und gegen ungewollte Laktation eingesetzt werden kann. Es wurden mit einer Ausnahme. wo Erbrechen auftrat, keine Nebenwirkungen gesehen.

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Pseudopregnancy in the bitch: the current view on aetiology and treatment

Cited by 20 publications

References 22 publications

Female Canine Sexual Behavior

Female Canine Sexual Behavior

A study of the aetiology of pseudopregnancy in the bitch and the effect of cabergoline therapy

The Use of Cabergoline for Treatment of Pseudopregnancy in Dogs with the Purpose of Suppressing Lactation

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