Pseudomembranous disease (ligneous inflammation) of the female genital tract, peritoneum, gingiva, and paranasal sinuses associated with plasminogen deficiency

Angela, C.; Prichard, Elizabeth; Richardson, Mary S.; Rasenberger, Kenneth P.; Weathers, Dwight R.; Neville, Brad W.

doi:10.1016/j.anndiagpath.2008.02.005

Cited by 22 publications

(19 citation statements)

References 31 publications

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“…10,12 The pseudomembrane formation can also develop on the mucosa of the oral cavity, the nasopharynx and the female genital tract. 3,9,13 When other tissues are involved, most reported oral lesions are observed together with ligneous eyelid lesions. 14 Similarly, our patient also had nodular eyelid lesions which had previously been excised at the age of 5 and histologically diagnosed as ligneous conjunctivitis.…”

Section: Discussionmentioning

confidence: 99%

Ligneous Periodontitis: A Case Report with Different Treatment Approaches and Eleven Years of Follow Up

Tüter¹,

Yıldırım²,

Toközlü³

2020

Turkiye Klinikleri J Case Rep

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ABS TRACT Ligneous mucosal disease is a rare, destructive condition of plasminogen deficiency characterized by generalized membranous gingival enlargement leading to rapid tooth loss. We report a case of long-standing, generalized ligneous periodontitis with an eleven years of follow-up. The patient did not have any extra oral lesions although she had been suffering from plasminogen deficiency. Treatment approaches had no benefit. An abnormal healing process is the main pathogenetic mechanism; still, intensive periodontal health care is essential for the patients who suffer from ligneous mucosal disease. This report describes a ligneous periodontitis case with a history of ligneous conjunctivitis and its clinical and histopathologic findings, therapeutic approaches and eleven years of follow-up.

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Section: Discussionmentioning

confidence: 99%

Ligneous Periodontitis: A Case Report with Different Treatment Approaches and Eleven Years of Follow Up

Tüter¹,

Yıldırım²,

Toközlü³

2020

Turkiye Klinikleri J Case Rep

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“…3,12,13 Other common symptom locations include the respiratory tract (20%), ears (14%), female genitourinary tract (9%), and kidneys (4%). 3,11,[15][16][17][18] Lesions are often inflamed and painful and can compromise organ function, resulting in life-threatening conditions including renal and respiratory failure (e.g., tracheobronchial lesions). 11,18 Central nervous system complications have been noted, including Dandy-Walker malformation and occlusive hydrocephalus 12 in 14% of children due to fibrin deposition in the cerebral ventricular system; shunts used to drain cerebrospinal fluid are prone to occlusion or poor peritoneal absorption, leading some neurosurgeons to recommend ventriculocholecystic shunts.…”

Section: Plasminogen Deficiencymentioning

confidence: 99%

An international registry of patients with plasminogen deficiency (HISTORY)

et al. 2020

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“…[2][3][4][5] Plazminojen eksikliği, ağız, göz, nasofarenks, trakea ve genital bölge mukozasında psödomembran ve kronik lezyonlar ile karakterize genetik bir hastalıktır. 6 Hastalık otozomal çekinik geçiş-lidir ve nadir görülür. Genellikle süt çocukları ve çocuk-lar etkilenmiştir, ancak hastalık herhangi bir yaşta da ortaya çıkabilir.…”

Section: Introductionunclassified

“…Ġlk rapor edilen vakalar hastalığın oldukça dikkat çekici ve ciddi olan göz bulguları üstünde yoğunlaşmaktadır. 6 Plg eksikliği lignöz konjonktivit ve lignöz periodontitis (LP) ile ilgilidir (%34).…”

Section: Introductionunclassified

“…Lezyon; ülsere plak, polip, veya nodül şeklindedir. 6 Hipoplazminojen eksikliğinde oluşan dişeti büyümeleri ve alveol kemik kayıpları; "Amiloidoz Ülseratif Gingival Hiperplazi" , "Destrüktif Membranöz Periodontal Hastalık" veya "Lignöz Periodontitis"" olarak adlandırılır. 13,14 Dişetindeki lezyonlar LP ile ilgilidir ve diş kaybı ile birlikte kaybolmaktadır.…”

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Li̇gnöz Peri̇odonti̇ti̇s : Olgu Sunumu

Aytekin¹,

Hatipoğlu²,

Özgöz³

et al. 2015

Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi

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Aim: Ligneous periodontitis is an infectious disease characterized by the inflammation of the supporting periodontal tissues, resulting in attachment and alveolar bone loss with plasminogen deficiency. This case report shows the treatment and follow-up of patient who have ligneous periodontitis.Case Report: Fifteen years old boy who had ligneous periodontitis applied to our periodontology clinic. Clinical and radiographic evaluation revealed severe periodontal breakdown around all teeth. Intraoral soft tissues were characterized by gingival reddening and swelling and the patient complained of periodic discharge of pus from the periodontal pockets, mobility, and severe pain. The probing depths were more than 7 mm %58 percent probing areas and there were radiolucent lesions around the teeth in panoramic radiograph.Full-mouth subgingival scaling and root planing under local anesthesia was performed and the pocket wall is gently retracted with a periodontal curette in an attempt to initiate drainage through the pocket entrance. Systemic amoxicillin and clavulanic acid applied for antibiotic therapy.Result: The goal of treatment was to create a clinical condition that is conducive to retaining as many teeth as possible for as long as possible but alveolar bone loss around the teeth was too severe. Systemic disorders such as plasminogen deficiency increase a patient's susceptibility to destructive periodontitis and have impacts on periodontal disease progression and severity.

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Pseudomembranous disease (ligneous inflammation) of the female genital tract, peritoneum, gingiva, and paranasal sinuses associated with plasminogen deficiency

Cited by 22 publications

References 31 publications

Ligneous Periodontitis: A Case Report with Different Treatment Approaches and Eleven Years of Follow Up

Ligneous Periodontitis: A Case Report with Different Treatment Approaches and Eleven Years of Follow Up

An international registry of patients with plasminogen deficiency (HISTORY)

Li̇gnöz Peri̇odonti̇ti̇s : Olgu Sunumu

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