Pruritus in two horses following epidurally administered morphine

Kalchofner, Karin; Kummer, M; Price, J.; Bettschart‐Wolfensberger, Regula

doi:10.2746/095777307x254545

Cited by 19 publications

(17 citation statements)

References 42 publications

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“…9-44), penicillin, acepromazine, trimethoprim-potentiated sulfonamide, and tiludronate. 12,34,37 Focal vasculitis and panniculitis have been seen following subcutaneous injections. One horse developed a painful, sterile pyogranulomatous dermatitis over the neck, ventrum, and limbs (Figs.…”

Section: Clinical Featuresmentioning

confidence: 99%

Immune-Mediated Disorders

Scott

2011

Equine Dermatology

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Section: Clinical Featuresmentioning

confidence: 99%

Immune-Mediated Disorders

Scott

2011

Equine Dermatology

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“…Pruritus following epidurally administered morphine has been described in humans, sheep, dogs and horses (1,16,27,30). Pruritus is the most common side effect in humans after intrathecal and epidural administration of opioids (6).…”

Section: Discussionmentioning

confidence: 99%

Incidence of delayed hair re-growth, pruritus, and urinary retention after epidural anaesthesia in dogs

Guerrero

Schweizer-Kölliker

et al. 2014

Tierarztl Prax Ausg K

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Summary Objective: Delayed hair re-growth, pruritus and urinary retention are known complications after epidural anaesthesia in dogs. The aim of this study was to prospectively evaluate the effect of epidurally administered drugs on the occurrence of these complications in dogs. Material and methods: Ninety dogs were included in this study. Eighty client-owned dogs undergoing surgery were randomly assigned to one of three epidural treatment groups: either morphine and bupivacaine (MB), bupivacaine (B), or saline solution 0.9% (S) was administered epidurally to these patients. Ten dogs were only clipped in the lumbosacral area (C). Follow-up started 4 weeks after clipping and was performed every 4–5 weeks in cases of delayed hair regrowth or pruritus. Hair re-growth in the lumbosacral area was observed and compared to hair re-growth in the surgical field and the fentanyl patch area. Cytological analysis and a trichogram were performed if hair re-growth was delayed after 6 months. Time interval to first urination postoperatively was recorded (n = 80). Results: Hair regrowth was delayed in 11 dogs (12.2%; B: n = 7, S: n = 2, MB: n = 1, C: n = 1) with no differences between groups. Pruritus was evident in two dogs (2.2%; MB: n = 1, S: n = 1). After 6 months, hair had started to re-grow in all but one dog (B). After 10 months the coat of this dog had re-grown. Time to first urination did not differ between groups. Conclusion and clinical relevance: No direct correlation between the particular drugs injected epidurally and delayed hair re-growth, pruritus and urinary retention could be shown. Dog owners should be informed that hair re-growth after epidural anaesthesia could be markedly delayed.

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“…Although pruritus after intrathecal or epidural anaesthesia occurs frequently in humans, it is rarely detected in domestic animal species. It has been reported in dogs, horses and in sheep, with the animals biting or mutilating their hindquarters . In this report, the development of hypotension and pruritus after intrathecal morphine and bupivacaine administration in a cat is presented.…”

mentioning

confidence: 88%

“…It has been reported in dogs, horses and in sheep, with the animals biting or mutilating their hindquarters. [1][2][3] In this report, the development of hypotension and pruritus after intrathecal morphine and bupivacaine administration in a cat is presented.…”

mentioning

confidence: 99%

Hypotension and pruritus induced by neuraxial anaesthesia in a cat

Bauquier

2012

Aust Veterinary J

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Although preventive epidural morphine administration with bupivacaine is effective in producing long-lasting analgesia, neuraxial anaesthesia can cause cardiovascular depression and pruritus. This report presents the development and treatment of hypotension and pruritus after intrathecal morphine and bupivacaine administration in a 3-year-old female spayed Domestic Short-hair cat presented for surgical repair of a torn right cranial cruciate ligament. Opioid-induced pruritus is not usually considered a frequently occurring complication, but may be easily misinterpreted as being dysphoria in recovery. It can be treated by administration of ondansetron, with human patients usually responding within 30 min after treatment.

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Pruritus in two horses following epidurally administered morphine

Cited by 19 publications

References 42 publications

Immune-Mediated Disorders

Immune-Mediated Disorders

Incidence of delayed hair re-growth, pruritus, and urinary retention after epidural anaesthesia in dogs

Hypotension and pruritus induced by neuraxial anaesthesia in a cat

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