PRRS: Effect on herd performance after initial infection and risk analysis

Brouwer, Jenny; Frankena, K.; Jong, M.F. de; Voets, R.; Dijkhuizen, A.A.; Verheijden, J.H.M.; Komijn, R.E.

doi:10.1080/01652176.1994.9694427

Cited by 22 publications

(17 citation statements)

References 5 publications

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“…Acute reproductive failure in sows was observed when PRRSV was introduced in the Tolakker herd, which agreed with numerous other reports [1,2,[24][25][26]. Four months later, the performance parameters returned to the level before the outbreak.…”

Section: Discussionsupporting

confidence: 89%

Introduction, persistence and fade-out of porcine reproductive and respiratory syndrome virus in a Dutch breeding herd: a mathematical analysis

Nodelijk

Jong²,

Nes

et al. 2000

Epidemiol. Infect.

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SUMMARYThe objective of this study was to investigate the dynamics of PRRSV infection and to quantify transmission within a breeding herd, and its impact on herd performance. For this purpose a longitudinal study was performed in a closed breeding herd of 115 sows. Statistical methods and Monte Carlo simulations based on stochastic SIR models were used to analyse the observational data. Moreover, a case-control study was performed to determine whether seroconversion of sows during gestation was associated with aberrant litters. The transmission parameter R was estimated to be 3n0 (95 % confidence interval 1n5-6n0) for the model version based on the most plausible assumptions that the infectious period lasts 56 days and no lifelong immunity exists after infection. Based on simulations using a breeding herd of equal size the average time-to-extinction was estimated to be 6 years ; using a herd of twice the size, it was 80 years. Furthermore, in contrast to the epidemic phase of the disease, the endemic phase was not detrimental to herd performance.

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Section: Discussionsupporting

confidence: 89%

Introduction, persistence and fade-out of porcine reproductive and respiratory syndrome virus in a Dutch breeding herd: a mathematical analysis

Nodelijk

Jong²,

Nes

et al. 2000

Epidemiol. Infect.

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“…Losses are extremely variable, both in extent and duration and it is important to discriminate between the effects of the disease in the epidemic and endemic phases. In many cases in Britain economic losses have been minimalbut others have reported extreme economic loss (Hoefling, 1990;Dykhuizen et al, 1991;Loula, 1991;Vogel et al, 1991;Frankena et al, 1992;Polson et al, 1992;White, 1992) varying between 1-25 pigs and £65 per sow per year (Blackburn, 1991;Mortensen & Madsen, 1992;Brouwer et al, 1994) and 0-20% of annual production (Lindhaus & Lindhaus, 1991;Raymakers, 1991;Van Alstine, 1991;Zinamerman, 1991) or an annual loss in the USA of $18 per finishing space (Moore et al, 1990). An additional burden may be loss of trading status for seropositive breeding stock.…”

Section: Economic Lossmentioning

confidence: 99%

Porcine reproductive and respiratory syndrome (PRRS): A review, with emphasis on pathological, virological and diagnostic aspects

Done¹,

Paton²,

White³

1996

British Veterinary Journal

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Despite early attempts to control the spread of the disease, porcine reproductive and respiratory syndrome (PRRS) has now become endemic in many countries including Britain. The occurrence of subclinical herd infections, the prolonged circulation of virus within herds and probable aerogenic virus spread all mitigated against the success of control measures. The origin of the disease is unknown but the causative agent has been shown to be an arterivirus with shared features to lactate dehydrogenase virus of mice. There is evidence of extreme genetic and antigenic variability between American and European isolates. PRRS virus has a predilection for alveolar macrophages and does not grow in most cell lines. In infected pigs, viraemia can persist for many weeks in the face of circulating antibodies and little is known about the mechanisms by which immunity to infection develops. A wide spectrum of disease has been reported from the field, accompanied in some cases by heavy economic losses. Reproductive and perinatal losses were most prominent when the disease first appeared. In the endemic phase, PRRS may be more significant as a contributory factor to a post-weaning respiratory syndrome of young pigs of 3-8 weeks. On-farm techniques have been developed to reduce the recycling of PRRS virus from older infected nursery pigs to the younger newly weaned pig. Vaccines are now marketed for the control of PRRS, but are not licensed for use in Britain. Improvements in knowledge of virion composition and antigenic stability and in the nature of the immune response of the pig should result in genetically engineered subunit vaccines becoming available. Diagnosis of PRRS is still difficult as many animals do not show clinical signs and may only be detected by serology and often only when other respiratory diseases are being investigated. Now that the infection is widespread, serological testing must be properly targeted and interpreted to give meaningful results about virus circulation. An increasing arsenal of diagnostic methods are becoming available to detect virus in both fresh and fixed specimens. The pathogenic mechanisms of PRRS remain poorly defined and more work is needed to reveal the nature of the interaction between PRRS virus and other factors in disease.

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“…La duración de las secuelas está relacionadas con la variación en las manifestaciones clínicas de la enfermedad. Al inicio, se caracteriza por una fuerte caída de los parámetros reproductivos, luego el PRRS se vuelve endémico, donde finalmente se recuperan los niveles reproductivos previos (Brouwer et al, 1994), aunque la infección mantiene las posibilidades de emerger después de un prolongado intervalo (López-Heydeck, 2015). 16 veces).…”

Section: Resultsunclassified

Síndrome Reproductivo Respiratorio Porcino: Presentación en el Tiempo y Efecto sobre los Parámetros Productivos y Reproductivos

Vergara

Vega-Vilca

Cerga

2017

Rev. investig. vet. Perú

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RESUMENEl objetivo del estudio fue evaluar la presentación del Síndrome Reproductivo Respiratorio Porcino (PRRS) en el tiempo y determinar el efecto que produce sobre las características productivas y reproductivas. Se evaluó el comportamiento productivo de 210 marranas Camborough 22, que parieron entre 2013 y 2015 en una granja porcina de Lima, Perú. Las características evaluadas fueron el promedio semanal/camada de lechones nacidos (NT), total de lechones nacidos vivos (NV), total de lechones nacidos muertos (NM), peso vivo de los lechones nacidos (PVLN), total de lechones destetados (LD), peso vivo de lechones destetados (PVLD), mortalidad de lechones al destete (MLD), peso vivo de lechones a los 70 días (PVL70) y mortalidad de lechones a los 70 días (ML70). El incremento de los NM superior a los límites normales de las gráficas de control duró 13 semanas, evidenciándose a partir de la semana 95 (cuarta semana octubre 2014) y se prolongó hasta la semana 108 (segunda semana febrero 2015). En el año de la presentación del PRRS, los NM, PVLN y ML70 se incrementaron en 2.3 veces, 6.8% y 13 veces, respectivamente (p<0.05), mientras que el NT, NV, LD, MLD y PVL70 disminuyeron en 16.4, 22.0, 20.5, 44.6 y 11.6%, respectivamente (p<0.05). La menor productividad redujo los ingresos por marrana/año hasta un 35.6%. El PRRS afectó los principales parámetros reproductivos y productivos evaluados hasta los 70 días de edad, generando pérdidas económicas.

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PRRS: Effect on herd performance after initial infection and risk analysis

Cited by 22 publications

References 5 publications

Introduction, persistence and fade-out of porcine reproductive and respiratory syndrome virus in a Dutch breeding herd: a mathematical analysis

Introduction, persistence and fade-out of porcine reproductive and respiratory syndrome virus in a Dutch breeding herd: a mathematical analysis

Porcine reproductive and respiratory syndrome (PRRS): A review, with emphasis on pathological, virological and diagnostic aspects

Síndrome Reproductivo Respiratorio Porcino: Presentación en el Tiempo y Efecto sobre los Parámetros Productivos y Reproductivos

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