PRP in the Treatment of Trochanteric Syndrome: A Pilot Study

Abstract

Objective: To compare the efficacy of platelet rich plasma (PRP) against corticosteroid on the treatment of trochanteric pain syndrome. Methods:From July 2011 to November 2012, eighteen patients (20 hips) with trochanter pain syndrome were randomized in two groups and treated with platelet rich plasma or triamcinolone infiltration guided by ultrasound. Pain and function were evaluated prior to the intervention and after 10, 30 and 60 days, through the Facial Expressions Scale for Pain and the Western Ontario McMaster and Harris Hip Score questionnaires. Inter-group analysis was performed by Student t-test and intragroup analysis by ANOVA, followed by Bonferroni post hoc test. Statistical significance was set at p <0.05. Results:There was no difference between the groups. The triamcinolone group showed pain reduction (p=0.004) and improved function (p=0.036) through the Harris Hip Score questionnaire at 10, 30 and 60 days after treatment, when compared with the pre- intervention period. The platelet rich plasma group showed no statistical improvement in any of the variables. Conclusion: Up to 60 days, PRP infiltration has no influence on pain relief and function improvement in trochanteric syndrome treatment. Level of Evidence II, Prospective Comparative Study.

Ultrasound-guided Platelet-rich Plasma Application Versus Corticosteroid Injections for the Treatment of Greater Trochanteric Pain Syndrome: A Prospective Controlled Randomized Comparative Clinical Study

“…Our findings are in full agreement with those of previous studies [25][26]. However, Ribeiro et al, in a comparative study of PRP injections and CSI in the treatment of GTPS, found no significant differences in clinical outcomes [24]. This disagreement with our study could be explained by the fact that each study used different PRP-preparation equipment, different preparation methods, different spinning protocol and different platelet and growth factor concentrations.…”

“…Some of them tried to compare the outcomes of PRP administration with other kinds of treatment [12,21]. A small number of these studies talk about the application of PRP injections in the treatment of GTPS and only a few of them compare this type of treatment with the use of CSI [22][23][24][25][26]. The purpose of our study was to evaluate and compare the outcomes of US-guided PRP injections against CSI in the treatment of GTPS.…”

A double blind randomised control trial investigating the efficacy of platelet rich plasma versus placebo for the treatment of greater trochanteric pain syndrome (the HIPPO trial): a protocol for a randomised clinical trial

“…They found ultrasound-guided intra-tendinous PRP injections to be a safe and effective treatment option for chronic recalcitrant gluteus medius tendinopathy due to moderate to severe tendinosis. A second report by Ribeiro et al from Brazil [ 23 ] was published in 2016 comparing the efficacy of PRP against corticosteroids. They concluded that during the first 2 months, which was the study period, the PRP has no influence on pain relief and functional improvement in trochanteric syndrome.…”

“…The trial design has been based on our local experience with using PRP in patients with GTPS and an RCT conducted by Monto et al in 2014 [ 22 ] comparing steroid injection with PRP in patients with severe hip bursitis. Add to this, a pilot study by Ribeiro et al in 2016 [ 23 ], which compared the efficacy of PRP against corticosteroid in the treatment of GTPS.…”

Does low back pain or leg pain in gluteus medius syndrome contribute to lumbar degenerative disease and hip osteoarthritis and vice versa? A literature review

“…Ultrasound-guided intratendinous PRP injection significantly improved ADL and function (HHS, HOS-ADL, HOS-Sports score) Ribeiro A et al 73) Patients with chronic GTPS (n=10)…”