Proximal fibular osteotomy for the management of medial compartment knee osteoarthritis: A systematic review and meta-analysis

Sugianto, Julius Albert; Hadipranata, Thirza; Lazarus, Gilbert; Amrullah, Ahmad Hannan

doi:10.1016/j.knee.2020.11.020

Cited by 11 publications

(9 citation statements)

References 32 publications

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“…There are many surgery options for medial compartment KOA when conservative measures cannot relieve pain or the knee joint has obvious deformities, such as high tibial osteotomy and total knee arthroplasty [ 4 ]. To date, total knee arthroplasty remains the most common and effective treatment choice for KOA patients, but the cost of surgery is high, and the procedure is invasive [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Gait Improvement in Patients with Knee Osteoarthritis after Proximal Fibular Osteotomy

Cao

et al. 2022

BioMed Research International

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Proximal fibula osteotomy (PFO) is a relatively new surgery to treat medial compartment knee osteoarthritis (KOA), which can improve varum deformity and relieve knee joint pain. However, the gait alterations in KOA patients after PFO are still poorly understood. The purpose of this study was to evaluate the gait patterns change in patients of medial compartment KOA after PFO. Gait data were collected for 9 females with unilateral medial compartment KOA before and at 6 months after PFO and also for 9 healthy age-matched females. Paired t -test was used to determine the effect of PFO within the KOA group, and independent t -test were performed to compare between KOA and control groups for spatiotemporal, kinematic, and kinetic variables. The results showed that patients with KOA had significantly increased knee peak flexion angle, knee sagittal range of motion, and peak external hip adduction moment but decreased knee frontal range of motion in the affected limb after PFO. The gait symmetry was improved postoperatively confirmed by single support and swing phases, knee peak flexion angle and sagittal range of motion, peak external hip and knee adduction moments, and peak anterior and peak posterior ground reaction forces. These findings provided evidence of a biomechanical benefit and gait improvement following PFO to treat medial compartment KOA.

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Section: Introductionmentioning

confidence: 99%

Gait Improvement in Patients with Knee Osteoarthritis after Proximal Fibular Osteotomy

Cao

et al. 2022

BioMed Research International

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“…Proximal fibular osteotomy is an effective method for treatment of early knee osteoarthritis ( 17 – 19 ). In addition, it has been confirmed that the pain relief and improvement are statistically significant ( 20 ). Due to fewer complications and easy operation, proximal fibular osteotomy is recommended in any treatment algorithm for MCKOA ( 21 , 22 ).…”

Section: Introductionmentioning

confidence: 80%

A new technique of autologous bone grafting for open-wedge high tibial osteotomy

Gong,

Jin,

Wang

et al. 2024

Front. Surg.

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PurposeThis study aimed to demonstrate the application of orthotopic bone flap transplantation with a fibula transplantation (OBFT-FT) in open-wedge high tibial osteotomy (OW-HTO) and to assess the effect of OBFT-FT on gap healing.Patients and methodsFrom January to July 2020, 18 patients who underwent OW-HTO with OBFT-FT were reviewed for this study. Demographics, postoperative complications, and radiological and clinical outcomes of patients were collected. Finally, the clinical outcomes of patients were analyzed.ResultsA total of 14 patients were included in this study. The average age and body mass index were 59.6 ± 9.2 years and 28.1 ± 4.5 kg/m2, respectively. The average correction angle and gap width were 9.5 ± 1.8° and 10.2 ± 2.7 mm, respectively. The rates of radiological gap healing at sixth week, third month, and sixth month were 42.9%, 85.7%, and 100%, respectively. The mean Lysholm score, International Knee Documentation Committee score, and visual analog scale scores at sixth-month follow-up were significantly better than the preoperative scores (p < 0.001, p < 0.001, p = 0.001, respectively). And, no delayed union or non-union, collapse, loss of correction, or surgical site infection were found.ConclusionsAs a new technique for autologous bone graft, the OBFT-FT could be successfully applied in the treatment of gap healing after OW-HTO, and excellent radiological and clinical outcomes could be seen on patients’ short-term follow-up.

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“…On this basis, the proximal fibula osteotomy (PFO) was designed to successfully relieve the pain by reducing the pressure in the medial compartment of the knee joint. PFO has the advantages of simple operation, small trauma, and less adverse reactions, therefore it has a promising clinical future ( Baldini et al, 2018 ; Sugianto et al, 2021 ). High tibial osteotomy (HTO), which improves knee function by shifting the force line of the knee joint, is also an important part of knee-protection treatment for OA.…”

Section: Current Oa Treatmentmentioning

confidence: 99%

Therapeutic potential of nanotechnology-based approaches in osteoarthritis

et al. 2022

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Osteoarthritis (OA) is a multifactorial disease that affects the entire joint, often resulting in severe pain, disability, psychological distress, and a lower quality of life. Patient self-management is emphasized in OA clinical recommendations. Currently, the clinical treatment of OA mainly focuses on pain relief and the improvement of joint function, with few options for regenerating degenerative cartilage or slowing the progression of OA. Therefore, we first reviewed the current treatment of OA, and then summarized the research advances of nanotechnology in OA treatment, including nano drug delivery systems for small molecule drugs, nucleic acids and proteins, nano-scaffolds for cartilage regeneration, and nanoparticle lubricants. Finally, we discussed the opportunities and potential challenges of nanotechnology in OA treatment.

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Proximal fibular osteotomy for the management of medial compartment knee osteoarthritis: A systematic review and meta-analysis

Cited by 11 publications

References 32 publications

Gait Improvement in Patients with Knee Osteoarthritis after Proximal Fibular Osteotomy

Gait Improvement in Patients with Knee Osteoarthritis after Proximal Fibular Osteotomy

A new technique of autologous bone grafting for open-wedge high tibial osteotomy

Therapeutic potential of nanotechnology-based approaches in osteoarthritis

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