Protracted venous infusion 5-fluorouracil in combination with subcutaneous interleukin-2 and alpha-interferon in patients with metastatic renal cell cancer

Allen, Mariet; Vaughan, M; Webb, Andrew R.; Johnston, Stephen; Savage, Paul; Eisen, Tim; Bates, S.; Morre, Jean; A’Hern, Roger; Gore, M.

doi:10.1016/s1078-1439(01)00161-2

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2005

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“…IL-2-therapy has been reported to yield a temporary survival benefit in a large percentage of advanced RCC patients. 5,11,12 In our study, we observed a longterm survival benefit of more than 10 years in a small proportion (6.3%; median follow-up, 141 months) of metastatic RCC patients. Data of other authors indicated that no more than 4.5%-9% of advanced metastatic RCC patients could survive for more than 5 years after treatment with cytokine therapy.…”

Section: Discussionsupporting

confidence: 46%