Proton Radiography Studies for Proton CT

Petterson, M.; Blumenkrantz, N.; Feldt, J.; Heimann, J.; Lucia, D.; Seiden, A.; Williams, D. C.; Sadrozinski, H. F-W.; Bashkirov, V.; Schulte, R.; Bruzzi, M.; Menichelli, D.; Scaringella, M.; Talamonti, Cinzia; Cirrone, G.A.P.; Cuttone, G.; Presti, D. Lo; Randazzo, N.; Sipala, V.

doi:10.1109/nssmic.2006.354367

Cited by 6 publications

(4 citation statements)

References 13 publications

(20 reference statements)

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“…For example, Fabrikant et al (1982) reported scanning a metastatic melanoma in the cerebral cortex of a patient with a 670 MeV/n neon ion beam. Schulte et al (2004) and Petterson et al (2006) measured the tracks of individual protons using both entrance and exit Si detectors and energy loss using scintillator-based calorimeters. Later, Schulte et al (2005) and gave specifications for a proton CT scanner both for imaging for treatment planning (optimized for accuracy) and for treatment verification (optimized for speed).…”

Section: Ion Computed Tomography Scanningmentioning

confidence: 99%

Acceptance Testing and Quality Control of Digital Radiographic Imaging Systems

Moyers¹,

Toth²,

Sadagopan³

et al. 2024

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Light ion beam treatments are becoming more widely used. Safe and optimal treatments may only be achieved when uncertainties are considered at every step of the planning and delivery process. These uncertainties include, but are not limited to, penetration uncertainties due to beam delivery, uncertainties in dose compliance, uncertainties of x-ray computed tomography numbers, absolute and relative linear stopping powers, absolute and relative linear scattering powers, conversion of x-ray computed tomography numbers to relative linear stopping power, lateral alignment uncertainties, and uncertainties due to inter-fractional and intra-fractional anatomical variations. Knowing the source and magnitude of these uncertainties, the planner must optimize the plans to mitigate the effect of these uncertainties as much as possible without making the plan undeliverable. Visualization of dose distributions considering the effects of these uncertainties is an important step in evaluating the safety and effectiveness of the plans. This report by Task Group 202 of the AAPM has endeavored to address each of these topics as a guide to the user of light ion beam treatments.

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Section: Ion Computed Tomography Scanningmentioning

confidence: 99%

Acceptance Testing and Quality Control of Digital Radiographic Imaging Systems

Moyers¹,

Toth²,

Sadagopan³

et al. 2024

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“…estimated in [11]: in a volume of 10 × 10 × 10 cm 3 , about 10 9 tracks have to be measured. Present state-of-the-art pCT prototypes made excellent advancements in the field, but they still show some limitations for a practical implementation.…”

Section: Proton Computed Tomographymentioning

confidence: 99%

iMPACT: An Innovative Tracker and Calorimeter for Proton Computed Tomography

Baruffaldi

Iuppa

Snoeys

2018

IEEE Trans. Radiat. Plasma Med. Sci.

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This contribution describes the first results obtained within the iMPACT project, which aims to build a novel proton computed-tomography (pCT) scanner for protons of energy up to 230 MeV, as used in hadron therapy. The iMPACT pCT scanner will improve the current state-of-the-art in proton tracking at all levels: speed, spatial resolution, material budget, and cost. We will first describe the design of the iMPACT scanner, which is composed by a tracker and a range calorimeter. We will then illustrate the results of a test with the ALPIDE sensor, a monolithic active pixels sensor, developed by the ALICE collaboration, which will equip the iMPACT tracker in this first phase. We finally detail the characterization building elements of the prototype of the range calorimeter, which is composed of segmented scintillator fingers readout by SiPMs. Reported beam-test data will highlight how the technological choices we made well address the performances of a state-of-the-art pCT system.

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“…The number of required protons has been estimated in Refs. [7] and [8], where the image quality was compared to the number of proton histories in the voxels. Stable solutions were found with 25 proton histories.…”

Section: Design Of the Pct Head Scannermentioning

confidence: 99%

Development of a head scanner for proton CT

Sadrozinski

Johnson

Macafee

et al. 2013

Nuclear Instruments and Methods in Physics Research Section A:

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We describe a new head scanner developed for Proton Computed Tomography (pCT) in support of proton therapy treatment planning, aiming at reconstructing an accurate map of the stopping power (S.P.) in a phantom and, in the future, in patients. The system consists of two silicon telescopes which track the proton before and after the phantom/patient, and an energy detector which measures the residual energy or range of the proton to reconstruct the Water Equivalent Path Length (WEPL) in the phantom. Based on the experience of the existing prototype and extensive Geant4 simulations and CT reconstructions, the new pCT scanner will support clinically useful proton fluxes.

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Proton Radiography Studies for Proton CT

Cited by 6 publications

References 13 publications

Acceptance Testing and Quality Control of Digital Radiographic Imaging Systems

Acceptance Testing and Quality Control of Digital Radiographic Imaging Systems

iMPACT: An Innovative Tracker and Calorimeter for Proton Computed Tomography

Development of a head scanner for proton CT

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