Acceptance Testing and Quality Control of Digital Radiographic Imaging Systems

Moyers, Michael F.; Toth, Thomas L.; Sadagopan, R; Chvetsov, A; Unkelbach, Jan; Mohan, Radhe; Lesyna, David; Lin, Liyong; Li, Zuofeng; Poenisch, Falk; Newhauser, Wayne D.; Farr, Johathan

doi:10.37206/202

Cited by 7 publications

(2 citation statements)

References 142 publications

(196 reference statements)

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“…Second, the neutron scatter, which is of concern regarding secondary cancer induction, is significantly reduced. On top of that, pencil beam scanning introduces the possibility of intensity-modulated proton therapy (IMPT) [10,11].…”

Section: Active Scanning Systems (Pencil Beam Scanning)mentioning

confidence: 99%

Interaction of proton beam with human tissues in proton therapy

Hazem

2023

Proton Therapy - Scientific Questions and Future Direction

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Proton therapy is an effective and safe method to treat tumors in human body. Instead of conventional radiation (X-rays), this technique uses a heavy charged particles (protons) to treat cancer. This chapter reviews the basic aspects of the physics of proton therapy, including proton beam properties, proton interaction mechanisms, and radiation effects induced in the human tissue. A more highly conformal technique of proton therapy called “pencil beam scanning”, based on intensity-modulated proton therapy (IMPT), will be also developed. The uncertainty in the determination of the relative biological effectiveness (RBE) will also be discussed in light of recent experimental results. We conclude the chapter by discussing future developments and potential challenges of proton therapy.

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Section: Active Scanning Systems (Pencil Beam Scanning)mentioning

confidence: 99%

Interaction of proton beam with human tissues in proton therapy

Hazem

2023

Proton Therapy - Scientific Questions and Future Direction

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“…In addition to the aforementioned IGRT and ART strategies for treatment delivery control, other useful tools such as the robust planning technique together with Monte-Carlo dose calculations are commonly used in proton treatments to minimize the impact of uncertainties associated with the dose calculation process itself (Paganetti 2012, Moyers et al 2020. In this case, there are two main root causes that explain this uncertainty: the stopping power ratio (SPR) characterization of the biological tissues and the calibration of the CT units employed to derive SPR in every voxel of the virtual simulation image (Schneider et al 1996, Ainsley andYeager 2014).…”

Section: Introductionmentioning

confidence: 99%

Material decomposition maps based calibration of dual energy CT scanners for proton therapy planning: a phantom study

Viar-Hernández,

Vera-Sánchez,

Schmidt-Santiago

et al. 2024

Phys. Med. Biol.

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We introduce a new calibration method for Dual Energy CT (DECT) based on Material Decomposition (MD) maps, specifically iodine and water MD maps. The aim of this method is to provide the first DECT calibration based on MD maps. The experiments were carried out using a General Electric (GE) Revolution CT scanner with ultra-fast kV switching and used a Density Phantom by GAMMEX for calibration and evaluation.The calibration process involves several steps. First, we tested the ability of MD values to reproduce Hounsfield Unit (HU) values of SECT acquisitions and it was found that the errors were below 1\%, validating their use for HU reproduction. Next, the different definitions of computed $Z$ values were compared and the robustness of the approach based on the materials' composition was confirmed. Finally, the calibration method was compared with a previous method by Bourque et al., providing a similar level of accuracy and superior performance in terms of precision.Overall, this novel DECT calibration method offers improved accuracy and reliability in determining tissue-specific physical properties. The resulting maps can be valuable for proton therapy treatments, where precise dose calculations and accurate tissue differentiation are crucial for optimal treatment planning and delivery.

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Clinical commissioning of intensity‐modulated proton therapy systems: Report of AAPM Task Group 185

Farr¹,

Moyers²,

Allgower

et al. 2020

Medical Physics

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Proton therapy is an expanding radiotherapy modality in the United States and worldwide. With the number of proton therapy centers treating patients increasing, so does the need for consistent, high-quality clinical commissioning practices. Clinical commissioning encompasses the entire proton therapy system's multiple components, including the treatment delivery system, the patient positioning system, and the image-guided radiotherapy components. Also included in the commissioning process are the x-ray computed tomography scanner calibration for proton stopping power, the radiotherapy treatment planning system, and corresponding portions of the treatment management system. This commissioning report focuses exclusively on intensitymodulated scanning systems, presenting details of how to perform the commissioning of the proton therapy and ancillary systems, including the required proton beam measurements, treatment planning system dose modeling, and the equipment needed.

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Acceptance Testing and Quality Control of Digital Radiographic Imaging Systems

Cited by 7 publications

References 142 publications

Interaction of proton beam with human tissues in proton therapy

Interaction of proton beam with human tissues in proton therapy

Material decomposition maps based calibration of dual energy CT scanners for proton therapy planning: a phantom study

Clinical commissioning of intensity‐modulated proton therapy systems: Report of AAPM Task Group 185

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