Doctors Trung Le and Daniel Ruterbories helped me with their expertise on a daily basis, also with unsurpassable quality and patience. A special mention to Doctor Leo Bellantoni, the first one to dedicate a lot of time an effort in myself as a grad student.My parents Irma and José who always showed me the example to follow and the inspiration to move forward. I cannot express how much I thank you for teaching me to pursue what I want.My siblings Pepe, Juan and Mariana, perhaps not aware of your contribution, thank you for always being there.My wife Maricruz and my Daughter AnaMá, my strongest reason, the pushing force, and the most precious beings I could ever met. I owe you so much, you have given me everything.