Proton computed tomography using a 1D silicon diode array

Wang, Peng; Cammin, J.; Bisello, F.; Solberg, Timothy D.; McDonough, James E.; Zhu, Timothy C.; Menichelli, D.; Teo, Boon K.

doi:10.1118/1.4963221

Cited by 3 publications

(2 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In integrating set-ups, range/WET information is obtained from each pencil beam spot or pixel (depending on the set-up) without resolving individual protons. Depending on the exact implementation, the average entry position is determined from the beam spot position (in an active scanned delivery system) and/or the average exit position from the pixel coordinate on the detector behind the patient (Zygmanski et al 2000, Schneider et al 2004, Telsemeyer et al 2012, Rinaldi et al 2013, Testa et al 2013, Farace et al 2016, Wang et al 2016.…”

Section: Introductionmentioning

confidence: 99%

Proton radiography with a commercial range telescope detector using dedicated post processing methods

Krah¹,

Marzi²,

Patriarca³

et al. 2018

Phys. Med. Biol.

View full text Add to dashboard Cite

Proton transmission imaging uses protons with high enough energy to fully traverse the phantom/patient and to be captured in a suitable detector placed behind it. The measured residual energy or residual range provide a direct estimate of the water equivalent thickness (WET) of the image volume. Requirements for proton imaging to be exploitable in clinical practice include: sufficient WET accuracy and integrability into the treatment room and the clinical workflow, as well as an acceptably low dose to the patient and a sufficient spatial resolution. In this work, we report on experiments performed at the Institut Curie-Proton therapy center in Orsay (IC-CPO), France, using a commercial range telescope commonly employed for quality assurance measurements. The purpose was to keep the experimental set-up as simple as possible and to achieve nonetheless high WET accuracy radiographies by developing and applying dedicated post processing methods. We explain these methods in detail and discuss their performance. We assess the WET accuracy based on two different reference phantoms: a CIRS electron density phantom with tissue equivalent inserts and a homogeneous step phantom. We find an agreement between the measured and the reference WET values of 0.2-0.5 mm. The lowest investigated dose was 10 mGy per acquisition. It could be lowered by modifying the irradiation plan and lowering the beam current, though the latter would impose slight optimisations of the detector hardware. Our work suggests that proton radiographies with good WET accuracy can be obtained with a reasonable experimental effort that would facilitate integration into clinical routine.

show abstract

Section: Introductionmentioning

confidence: 99%

Proton radiography with a commercial range telescope detector using dedicated post processing methods

Krah¹,

Marzi²,

Patriarca³

et al. 2018

Phys. Med. Biol.

View full text Add to dashboard Cite

show abstract

“…Many position sensitive electronic and solid-state detectors have been developed over the years, mainly to support hadron therapy (Poludniowski, Allinson, and Evans, 2015;Johnson, 2018). These include diodes (Wang et al, 2016;Briz et al, 2022), multiwire gas-proportional counters (Sauli, 2014), and cadmium zinc telluride detectors (Simos et al, 2009). However, these detectors suffer from lower spatial resolution and lower sensitivity than CR-39 and RCF, and conversely more sensitivity to noise from EMP due to short-pulse lasers.…”

Section: B Advanced Detectorsmentioning

confidence: 99%

Proton imaging of high-energy-density laboratory plasmas

Schaeffer,

Bott,

Borghesi

et al. 2023

Rev. Mod. Phys.

View full text Add to dashboard Cite

Proton imaging has become a key diagnostic for measuring electromagnetic fields in high-energydensity (HED) laboratory plasmas. Compared to other techniques for diagnosing fields, proton imaging is a measurement that can simultaneously offer high spatial and temporal resolution and the ability to distinguish between electric and magnetic fields without the protons perturbing the plasma of interest. Consequently, proton imaging has been used in a wide range of HED experiments, from

show abstract

First application of a high‐resolution silicon detector for proton beam Bragg peak detection in a 0.95 T magnetic field

et al. 2019

View full text Add to dashboard Cite

PurposeTo report on experimental results of a high spatial resolution silicon‐based detector exposed to therapeutic quality proton beams in a 0.95 T transverse magnetic field. These experimental results are important for the development of accurate and novel dosimetry methods in future potential real‐time MRI‐guided proton therapy systems.MethodsA permanent magnet device was utilized to generate a 0.95 T magnetic field over a 4 × 20 × 15 cm3 volume. Within this volume, a high‐resolution silicon diode array detector was positioned inside a PMMA phantom of 4 × 15 × 12 cm3. This detector contains two orthogonal strips containing 505 sensitive volumes spaced at 0.2 mm apart. Proton beams collimated to a circle of 10 mm diameter with nominal energies of 90 MeV, 110 MeV, and 125 MeV were incident on the detector from an edge‐on orientation. This allows for a measurement of the Bragg peak at 0.2 mm spatial resolution in both the depth and lateral profile directions. The impact of the magnetic field on the proton beams, that is, a small deflection was also investigated. A Geant4 Monte Carlo simulation was performed of the experimental setup to aid in interpretation of the results.ResultsThe nominal Bragg peak for each proton energy was successfully observed with a 0.2 mm spatial resolution in the 0.95 T transverse magnetic field in both a depth and lateral profiles. The proton beam deflection (at 0.95 T) was a consistent 2 ±0.5 mm at the center of the magnetic volume for each beam energy. However, a pristine Bragg peak was not observed for each energy. This was caused by the detector packaging having small air gaps between layers of the phantom material surrounding the diode array. These air gaps act to degrade the shape of the Bragg peak, and further to this, the nonwater equivalent silicon chip acts to separate the Bragg peak into multiple peaks depending on the proton path taken. Overall, a promising performance of the silicon detector array was observed, however, with a qualitative assessment rather than a robust quantitative dosimetric evaluation at this stage of development.ConclusionsFor the first time, a high‐resolution silicon‐based radiation detector has been used to measure proton beam Bragg peak deflections in a phantom due to a strong magnetic field. Future efforts are required to optimize the detector packaging to strengthen the robustness of the dosimetric quantities obtained from the detector. Such high‐resolution silicon diode arrays may be useful in future efforts in MRI‐guided proton therapy research.

show abstract

Proton computed tomography using a 1D silicon diode array

Abstract: The results demonstrate the feasibility of using silicon diode arrays for proton imaging. Such a device can potentially offer fast image acquisition and high spatial and energy resolution for PR and PCT.

Cited by 3 publications

References 30 publications

Proton radiography with a commercial range telescope detector using dedicated post processing methods

Proton radiography with a commercial range telescope detector using dedicated post processing methods

Proton imaging of high-energy-density laboratory plasmas

First application of a high‐resolution silicon detector for proton beam Bragg peak detection in a 0.95 T magnetic field

Contact Info

Product

Resources

About