Proto-Surgery in Ancient Egypt

Sullivan, Richard

doi:10.14712/18059694.2019.174

Cited by 11 publications

(2 citation statements)

References 29 publications

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“…The likelihood that hands were taken from captives is low, since this would limit their potential as future slaves 45 . Because corporeal integrity was vital for survival in the Ancient Egyptian view of the afterlife 46 , the victim’s impairment adds a deeper dimension to this act of dominance.…”

Section: Resultsmentioning

confidence: 99%

First osteological evidence of severed hands in Ancient Egypt

Gresky

Bietak

Petiti

et al. 2023

Sci Rep

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For the first time, the severed right hands of 12 individuals have been analysed osteologically. The hands were deposited in three pits within a courtyard in front of the throne room of a 15th Dynasty (c.1640–1530 BC) Hyksos palace at Avaris/Tell el-Dab‘a in north-eastern Egypt. Although this kind of practice is known from tomb or temple inscriptions and reliefs from the New Kingdom onwards, this is the first time that physical evidence has been used to learn more about the procedure and the individuals whose hands were taken. Here, we show that the right hands belonged to at least 12 adults, 11 males, and possibly one female. It is unclear if the hands were taken from dead or living individuals. After removing any attached parts of the forearm, the hands were placed in the ground with wide-splayed fingers, mainly on their palmar sides. The osteological analysis not only supports the archaeological interpretation of this evidence but also adds more detail regarding trophy-taking practices in Ancient Egypt.

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Section: Resultsmentioning

confidence: 99%

First osteological evidence of severed hands in Ancient Egypt

Gresky

Bietak

Petiti

et al. 2023

Sci Rep

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“…Surgery is essential for global cancer therapy, especially solid organ cancers, which has a long and distinguished history. It plays a vital role in cancer prevention, diagnosis, treatment, and reconstruction ( 8 , 9 ). Previous evidence indicated that more than 80% of patients with cancer may require surgery for the removal in 2015.…”

Section: Introductionmentioning

confidence: 99%

Local Anesthetic Lidocaine and Cancer: Insight Into Tumor Progression and Recurrence

Zhang

Xie

2021

Front. Oncol.

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Cancer is a leading contributor to deaths worldwide. Surgery is the primary treatment for resectable cancers. Nonetheless, it also results in inflammatory response, angiogenesis, and stimulated metastasis. Local anesthetic lidocaine can directly and indirectly effect different cancers. The direct mechanisms are inhibiting proliferation and inducing apoptosis via regulating PI3K/AKT/mTOR and caspase-dependent Bax/Bcl2 signaling pathways or repressing cytoskeleton formation. Repression invasion, migration, and angiogenesis through influencing the activation of TNFα-dependent, Src-induced AKT/NO/ICAM and VEGF/PI3K/AKT signaling pathways. Moreover, the indirect influences are immune regulation, anti-inflammation, and postoperative pain relief. This review summarizes the latest evidence that revealed potential clinical benefits of lidocaine in cancer treatment to explore the probable molecular mechanisms and the appropriate dose.

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Perspectives in pediatric neurosurgery

Mainprize

Taylor

Rutka³

2000

Child's Nervous System

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The new millennium beckons for novel advances in the diagnosis and treatment of pediatric neurosurgical conditions. Almost every aspect of pediatric neurosurgery has changed over the last decade. Undoubtedly with the application of knowledge in molecular biology to human disease many aspects of neurosurgery, especially neuro-oncology and the field of neuro-developmental anomalies, will change appreciably over the next decade. Overall, the trend in surgery in general and neurosurgery in particular is toward less invasive procedures and possibly non-surgical interventions. This review will briefly cover many of the important areas of pediatric neurosurgery. We will describe the state-of-the-art of our subspecialty and discuss possible future directions.

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Proto-Surgery in Ancient Egypt

Cited by 11 publications

References 29 publications

First osteological evidence of severed hands in Ancient Egypt

First osteological evidence of severed hands in Ancient Egypt

Local Anesthetic Lidocaine and Cancer: Insight Into Tumor Progression and Recurrence

Perspectives in pediatric neurosurgery

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