Proteomics in Context of Systems Biology

Souchelnytskyi, Serhiy

doi:10.1002/9780470369630.ch46

Cited by 2 publications

(2 citation statements)

References 81 publications

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“…Forty years can be considered a long time, but the fact is that the study of proteins within the term proteomics (Wilkins et al, ) is quite young, fluid, and diversifying as a technology. Being part of the three young high‐throughput omics technologies of genomics (transcriptomics), proteomics, and metabolomics, which are now, allied to high‐throughput phenotyping (phenomics), and being amalgamated into the field of systems biology (Ward & White, ; Bradshaw & Burlingame, ; Bradshaw, ; Souchelnytskyi, ; Coruzzi, Rodrigo, & Guttierrez, ). The relatively younger face of plant proteomics can be realized when we see its wide‐spread application in isolation, identification & cataloguing of proteins, and addressing/answering biological questions from 2000 to now, more than a decade of research in plant proteomics (for reviews and books see, Finnie, ; Samaj & Thelen, ; Thiellement, ; Agrawal & Rakwal, ; Ranjithakumari, ; Weckwerth et al, ; Agrawal et al, ) (Fig.…”

Section: Plant Proteomics and Mass Spectrometry: A Decadementioning

confidence: 99%

A decade of plant proteomics and mass spectrometry: Translation of technical advancements to food security and safety issues

Agrawal¹,

Sarkar

Righetti

et al. 2013

Mass Spectrometry Reviews

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Agrawal, G.K. et al. (2013). A decade of plant proteomics and mass spectrometry: Translation of technical advancements to food security and safety issues. AbstractTremendous progress in plant proteomics driven by mass spectrometry (MS) techniques has been made since 2000 when few proteomics reports were published and plant proteomics was in its infancy. These achievements include the refinement of existing techniques and the search for new techniques to address food security, safety, and health issues. It is projected that in 2050, the world's population will reach 9-12 billion people demanding a food production increase of 34-70% (FAO, 2009) from today's food production. Provision of food in a sustainable and environmentally committed manner for such a demand without threatening natural resources, requires that agricultural production increases significantly and that postharvest handling and food manufacturing systems become more efficient requiring lower energy expenditure, a decrease in postharvest losses, less waste generation and food with longer shelf life. There is also a need to look for alternative protein sources to animal based (i.e., plant based) to be able to fulfill the increase in protein demands by 2050. Thus, plant biology has a critical role to play as a science capable of addressing such challenges. In this review, we discuss proteomics especially MS, as a platform, being utilized in plant biology research for the past 10 years having the potential to expedite the process of understanding plant biology for human benefits. The increasing application of proteomics technologies in food security, analysis, and safety is emphasized in this review. But, we are aware that no unique approach/technology is capable to address the global food issues. Proteomics-generated information/resources must be integrated and correlated with other omics-based approaches, information, and conventional programs to ensure sufficient food and resources for human development now and in the future

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Section: Plant Proteomics and Mass Spectrometry: A Decadementioning

confidence: 99%

A decade of plant proteomics and mass spectrometry: Translation of technical advancements to food security and safety issues

Agrawal¹,

Sarkar

Righetti

et al. 2013

Mass Spectrometry Reviews

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“…Herein, we have seen progress on three main fronts: transcriptomics, proteomics and metabolomics, for system‐wide profiling of genes, proteins and metabolites, respectively 31–33. These disciplines have been loosely grouped into ‘systems biology’ 34–38 with the goal of modeling, prediction and design of new plants tailored to specific uses. The rapid development of genomics tools has proven indispensable to fully exploit these genomic sequences in the quest toward a fundamental understanding of the plant system.…”

Section: Proteomics Of Plant Biologymentioning

confidence: 99%

Time to articulate a vision for the future of plant proteomics – A global perspective: An initiative for establishing the International Plant Proteomics Organization (INPPO)

Agrawal¹,

Job

Zivy

et al. 2011

Proteomics

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Given the essential role of proteomics in understanding the biology of plants, we are establishing a global plant proteomics organization to properly organize, preserve and disseminate collected information on plant proteomics. We call this organization 'International Plant Proteomics Organization (INPPO; http://www.inppo.com).' Ten initiatives of INPPO are outlined along with how to address them in multiple phases. As our vision is global, we sincerely hope the scientific communities around the world will come together to support and join INPPO.

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Proteomics in Context of Systems Biology

Cited by 2 publications

References 81 publications

A decade of plant proteomics and mass spectrometry: Translation of technical advancements to food security and safety issues

A decade of plant proteomics and mass spectrometry: Translation of technical advancements to food security and safety issues

Time to articulate a vision for the future of plant proteomics – A global perspective: An initiative for establishing the International Plant Proteomics Organization (INPPO)

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