Protein-Directed Synthesis of γ-Fe₂O₃Nanoparticles and Their Magnetic Properties Investigation

Abstract

In this study, maghemite (γ-Fe 2 O 3 ) nanoparticles were produced using gelatin protein as an effective mediator. Size, shape, surface morphology and magnetic properties of the prepared γ-Fe 2 O 3 nanoparticles were characterized using XRD, FT-IR, TEM, SEM and VSM data. The effects of furnace temperature and time of heating together with the amount of gelatin on the produced gelatin-Fe 3 O 4 nanocomposite were examined to prove the fundamental effect of gelatin; both as a capping agent in the nanoscale synthesis and as the director of the spinel γ-Fe 2 O 3 synthesis among possible Fe 2 O 3 crystalline structures.

An electrochemical sensor based on iron(ii,iii)@graphene oxide@molecularly imprinted polymer nanoparticles for interleukin-8 detection in saliva

“…All these are in favour of large adsorption capacity. The colour of the nanoparticles has changed from black to brown, for some Fe 3 O 4 nanoparticles' oxidation to γ-Fe 2 O 3 [25]. The results showed that when 2θ is in the range of 5~80°, the six characteristic peaks of Fe 3 O 4 (2θ=30.1°, 35.5°, 43.1°, 53.4°, 57.0°, 62.6°) existed.…”

“…In aqueous solution, the template protein and functional monomer can form complex through the -OH of the monomer and amino acid of the protein. However, 25 decreasing cross-linking increases spatial fluctuations in the recognition sites and hence reduces binding efficiency. The Fe 3 O 4 @GO@MIP nanoparticles were fixed on the Au electrode in this way (Fig.1).…”

“…But such high saturation magnetization is enough for separation of nanoparticles from suspension in magnetic field, which facilitates the massive magnetic separation. 25 CV effectively and conveniently monitors the electron transmission of the modified electrode [26].…”

“…The survival rate of oral cancer is 60-80% when detected during its early stage; however, this number drops to 30-40% when the cancer is diagnosed during the advanced stages [2]. Indentifying molecular markers of early disease can 25 aid in early diagnosis, which can improve patient prognosis. IL-8, a salivary biomarker for early stage oral squamous cell carcinoma, was discovered through a previous tissue-based expression profiling effort [3].…”

“…First, IL-8 surface imprinted polymer nanoparticles are synthesized, with graphene oxide modified Fe 3 O 4 nanoparticles as the core and IL-8 imprinted polymer as the shell. 25 3-Aminophenylboronic acid (APBA), methylene bisacrylamide (MBA), N,N,N',N''-tetramethylenebisacrylamide (TEMED), and ammonium persulfate were all purchased from Alfa aesar (USA). When using the fast binding kinetics and super-paramagnetic features of the iron oxide core, the usual electrode modification step can be replaced by magnetic selfassembly.…”