Protein calorie malnutrition: Is the basic anomaly in insulin secretion or tissue receptors?

Thakur, Vikram; Singh, Oinam Joychandra; Mittal, Ashish; Karmarkar, M. G.; Ahuja, M. M. S.

doi:10.1007/bf02341512

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1990

1993

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“…Nevertheless the results are in agreement with those from studies in malnourished children in which low erythrocyte insulin receptor affinity was also found (Payne-Robinson et al 1988). In the malnourished rat hepatocyte, low receptor affinity was also found, but this was associated with an increase in receptor concentration (Thakur et al 1988). In healthy men with marginal energy deficiency, erythrocyte insulin binding was 16 YO decreased but receptor affinity was not altered (Garre1 et al.…”

Section: Discussionmentioning

confidence: 99%