Protein adsorption on gradient surfaces on polyethylene prepared in a shielded gas plasma

Spijker, Hendrikje; Bos, Roelof; Oeveren, Willem van; Vries, J. de; Busscher, Hj

doi:10.1016/s0927-7765(99)00056-9

Cited by 51 publications

(36 citation statements)

References 21 publications

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“…Chemical conversion of a pre-formed surface chemistry has been reported either directly by UV irradiation [142], which alone can give a gradient dependent on time [140,143] or via a chemically initiated reaction with surface bound molecules [144]. Irradiation and chemical etching techniques have been used to create gradients in surface oxygenated species dependent upon the time of exposure [145,146], or aggressiveness of the treatment [147,148]. Spijker et al fabricated wettability gradients on low density polyethylene by means of glow discharge in a partly shielded argon plasmas [148].…”

Section: Gradient Surface Chemistrymentioning

confidence: 99%

“…Irradiation and chemical etching techniques have been used to create gradients in surface oxygenated species dependent upon the time of exposure [145,146], or aggressiveness of the treatment [147,148]. Spijker et al fabricated wettability gradients on low density polyethylene by means of glow discharge in a partly shielded argon plasmas [148]. WCAs ranging from 100°to 40°were measured correlating with XPS to show a chemical gradient of oxidised groups on the surface.…”

Section: Gradient Surface Chemistrymentioning

confidence: 99%

See 1 more Smart Citation

Surface strategies for control of neuronal cell adhesion: A review

Roach

Parker

Gadegaard

et al. 2010

Surface Science Reports

156

133

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Section: Gradient Surface Chemistrymentioning

confidence: 99%

Section: Gradient Surface Chemistrymentioning

confidence: 99%

Surface strategies for control of neuronal cell adhesion: A review

Roach

Parker

Gadegaard

et al. 2010

Surface Science Reports

156

133

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“…The etching extent of a surface is gradually weakened by partly keeping off the particles. Spijker et al [51] generated a gradient surface by positioning an aluminium shield over the sample. The slope of the resulting gradient could be conveniently tuned by changing the distance between the cover and the sample.…”

Section: Plasmamentioning

confidence: 99%

Gradient biomaterials and their influences on cell migration

et al. 2012

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Cell migration participates in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. The cells specifically migrate to destiny sites induced by the gradually varying concentration (gradient) of soluble signal factors and the ligands bound with the extracellular matrix in the body during a wound healing process. Therefore, regulation of the cell migration behaviours is of paramount importance in regenerative medicine. One important way is to create a microenvironment that mimics the in vivo cellular and tissue complexity by incorporating physical, chemical and biological signal gradients into engineered biomaterials. In this review, the gradients existing in vivo and their influences on cell migration are briefly described. Recent developments in the fabrication of gradient biomaterials for controlling cellular behaviours, especially the cell migration, are summarized, highlighting the importance of the intrinsic driving mechanism for tissue regeneration and the design principle of complicated and advanced tissue regenerative materials. The potential uses of the gradient biomaterials in regenerative medicine are introduced. The current and future trends in gradient biomaterials and programmed cell migration in terms of the long-term goals of tissue regeneration are prospected.

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“…Over the past few years, a number of gradient surfaces have been developed by various methods for numerous practical applications, [1][2][3][4][5][6][7][8][9][10][11][12][13][14] such as protein adsorption, cell-motility studies, microfluidics, and combinatorial studies.…”

Section: Introductionmentioning

confidence: 99%