Protective Effects of the Aerial Parts of<i>Salvia officinalis, Melissa officinalis</i>and<i>Lavandula angustifolia</i>and their Constituents against Enzyme-Dependent and Enzyme-Independent Lipid Peroxidation

Hohmann, Judit; Zupkó, István; Rédei, Dóra; Csányi, Mihály; Fekete, György; Máthé, Imre; Janicsák, Gábor

doi:10.1055/s-2006-960830

Cited by 164 publications

(91 citation statements)

References 1 publication

(1 reference statement)

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“…Sage is largely used as a savory food flavouring either as dried leaves or essential oil (Perry et al, 1999;Tsai & Yang, 2011).It is also used traditionally in food preparation. (Cuvelier et al, 1994;Hohmann et al, 1999;Lu and Foo, 2001;Wang et al, 1998;Zupko et al, 2001). Sage leaves was one of the favourite candidate species as a source of natural antioxidants in health care products.…”

Section: Introductionmentioning

confidence: 99%

Physicochemical and Sensory Properties of Labneh Fortified with Salvia Officinalis

Habib

Shamsia

Awad

et al. 2017

Alexandria Science Exchange Journal

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Labneh is one of the most popular dairy products in the Middle East and has gained immense popularity due to its higher nutritional value compared to traditional yogurt. Labneh is defined as a concentrated yogurt in which yogurt is concentrated by removing acidic whey from the solid parts. Sage Salvia officinalis and olive oil have many health benefits as good source of antioxidant compounds. In this study, sage powder and olive oil were in Labneh for increasing its health benefits. The incorporated results showed that the sage powder has no influence on pH, chemical composition and rheological properties, while olive oil significantly reduced the hardness and viscosity of Labneh. The treatments of Labneh with sage powder and olive oil were highly accepted in flavor by panelists. This study recommended that the adding of sage powder could be a good source of antioxidant compounds to increase the health benefits of labneh.

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Section: Introductionmentioning

confidence: 99%

Physicochemical and Sensory Properties of Labneh Fortified with Salvia Officinalis

Habib

Shamsia

Awad

et al. 2017

Alexandria Science Exchange Journal

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“…The clinical relevance of these findings was emphasized by the observation that patients did not experience any adverse effect while taking sage. Pharmacological activities of sage relevant (Howes et al, 2003) to AD include antioxidant activity (Hohmann et al, 1999), anti-inflammatory effects (Baricevic et al, 2001), and cholinesterase inhibition (Perry et al, 1996). However, the precise mode of sage-protective action remains elusive.…”

mentioning

confidence: 99%

The Spice Sage and Its Active Ingredient Rosmarinic Acid Protect PC12 Cells from Amyloid-β Peptide-Induced Neurotoxicity

Iuvone

Filippis

Esposito

et al. 2006

J Pharmacol Exp Ther

218

120

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Traditional use and clinical reports suggest that the culinary herb sage (Salvia officinalis) may be effective for patients with mild to moderate Alzheimer's disease (AD). In this study, we evaluated the effect of a standardized extract from the leaves of S. officinalis (SOE) and its active ingredient rosmarinic acid on Alzheimer amyloid-␤ peptide (A␤)-induced toxicity in cultured rat pheochromocytoma (PC12) cells. Incubation of PC12 cells with A␤ (fragment 1-42) for 24 h caused cell death, and this effect was reduced by SOE and its active ingredient, rosmarinic acid. Rosmarinic acid reduced a number of events induced by A␤. These include reactive oxygen species formation, lipid peroxidation, DNA fragmentation, caspase-3 activation, and tau protein hyperphosphorylation. Moreover, rosmarinic acid inhibited phosphorylated p38 mitogen-activated protein kinase but not glycogen synthase kinase 3␤ activation. These data show the neuroprotective effect of sage against A␤-induced toxicity, which could validate the traditional use of this spice in the treatment of AD. Rosmarinic acid could contribute, at least in part, for sage-induced neuroprotective effect.

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“…Similarly, a phenolic compound from L. angustifolia prevented the development of oxidative rancidity in vegetable oils in a dose dependent manner comparable to 200 ppm butylated hydroxyanisole (BHA) and BHT [78]. Extracts of L. angustifolia exerted a concentration-dependent inhibition against both enzymedependent and enzyme-independent lipid peroxidation [79]. Blazekovic et al [80] obtained correlation coefficients which exhibited a strong positive association among different modes of antioxidant action (antiradical activity, reducing power and inhibition of lipid peroxidation) and contents of phenolic acids and total polyphenols in lavander extracts, indicating that phenolic compounds could be the major contributors to their antioxidant properties.…”

Section: Salvia Officinalis Salvia Officinalis L (Common Sagementioning

confidence: 99%

Biological effects of four frequently used medicinal plants of Lamiaceae

Srančíková¹,

Horvathova²,

Kozics³

2014

neo

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Cancer is one of the leading causes of death characterized by uncontrolled growth and spread of cancer cells. There are several hundred thousands of new cases of cancer worldwide. Clinical oncology is still challenged by toxicity and side effects of multimodal therapy strategies in which it is associated with poor prognosis for patients. There is an urgent necessity to develop novel therapy strategies and to utilize preventive potential of natural compounds. As the majority of anticancer drugs are of natural origin, natural products represent a valuable source for the identification and development of novel treatment options and chemopreventive mechanisms for cancer. This review is focused on the summary of published knowledges on the antioxidant and potential chemopreventive effects of biologically active substances present in the extracts of four plants of the family Lamiaceae (sage, thyme, rosemary and lavander) in different animal and in vitro systems. It is assumed that the chemopreventive and chemotherapeutic potential of natural compounds is the result of a combined action of several mechanisms.

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Protective Effects of the Aerial Parts ofSalvia officinalis, Melissa officinalisandLavandula angustifoliaand their Constituents against Enzyme-Dependent and Enzyme-Independent Lipid Peroxidation

Cited by 164 publications

References 1 publication

Physicochemical and Sensory Properties of Labneh Fortified with Salvia Officinalis

Physicochemical and Sensory Properties of Labneh Fortified with Salvia Officinalis

The Spice Sage and Its Active Ingredient Rosmarinic Acid Protect PC12 Cells from Amyloid-β Peptide-Induced Neurotoxicity

Biological effects of four frequently used medicinal plants of Lamiaceae

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