Protective effects of fraction 1a of polysaccharides isolated from Solanum nigrum Linne on thymus in tumor-bearing mice

Experimental immunology Influence of polysaccharide fraction C isolated from Caltha palustris L. on T and B lymphocyte subsets in mice

“…Polysaccharide compounds in other plants (such as Solanum nigrum, Opilia celtidifolia, Potentilla anserina) have been reported to have immunomodulating activities [12][13][14]. In the present study, we confirmed these properties also in polysaccharide fraction C of Caltha palustris.…”

“…CD4 + and CD8 + are also two subpopulations which, in peripheral blood, play a crucial role in adult host defense toward cancer [19]. Li et al [12] demonstrated the protective effect of fraction 1a of polysaccharides, isolated from Solanum nigrum Linne (SNL-P1a), on thymus in tumorbearing mice. They studied the profile of CD4 + and CD8 + in PBMC (peripheral blood mononuclear cell) and showed that treatment with SNL-P1a following tumor implantation caused a significant increase in the number of CD4 + T-lymphocyte and a decrease in the number of CD8 + T-lymphocyte in peripheral blood of tumor-bearing mice.…”

Experimental immunology Modulation of murine T and B lymphocyte subsets by polysaccharide fraction B isolated from Caltha palustris L.

“…Many polysaccharide compounds in other plants (such as Solanum nigrum, Opilia celtidifolia, Potentilla anserina) have been reported to have immunomodulating properties [15][16][17]. The most meaningful parameters for evaluating the balanced state of immunomodulation and homeostatic responses of the intrinsic immune system are the number and ratio of two main lymphocyte T subsets (CD4 + cells -T helpers, and CD8 + cells -T cytotoxic/suppressors) [18].…”

“…The fraction 1a of polysaccharides, isolated from Solanum nigrum Linne (SNL-P1a) has been demonstrated to have a protective effect on thymus in tumor-bearing mice. Li et al [15] T-lymphocyte in peripheral blood of tumor-bearing mice.…”

Scientific evaluation of medicinal plants used for the treatment of abnormal uterine bleeding by Avicenna

“…Aqueous extract as wells as polysaccharides isolated from S. nigrum exert antitumor activity on cervical cancer bearing mice [93][94][95].…”